Principal IT Applications Analyst - Lab Systems

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal IT Applications Analyst to join our IOPS IT team, serving as the principal technical liaison between lab-based business stakeholders and IT — ensuring business-critical applications are stable, supported, and continuously improving. In this role, you will deliver Tier 3 application support, lead root cause analysis, manage integrations, and drive permanent corrective actions — while collaborating with network and infrastructure teams, business owners, and cross-functional partners. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Troy, New York, United States
• Work model: Monday - Friday 8am - 4:30pm, onsite

Discover your role:

• Deliver Tier 3 application support including root cause analysis and implementation of permanent corrective actions; diagnose network-related issues affecting application performance and availability including connectivity, name resolution, certificates, and firewall rules in partnership with network and infrastructure teams
• Configure, test, and promote changes through controlled environments in accordance with change management and release procedures; support system integrations including diagnosis and resolution of data flow and interface failures across servers, databases, and connected systems
• Develop and execute test documentation, maintaining traceability from requirements through objective evidence; provide audit support with clear, traceable evidence covering access controls, change history, and data integrity
• Collaborate with business owners to translate requests into well-defined, prioritized work; communicate complex technical issues clearly and effectively to non-technical stakeholders at all levels
• Mentor junior analysts and maintain operational runbooks to ensure knowledge is shared and sustained across the team

This role requires:

• Bachelor’s degree in Information Technology, Computer Science, or related degree
• Principal IT Applications Analyst: 8+ years work experience
• Staff IT Applications Analyst: 10+ years work experience
• May consider equivalent combination of education and experience; level determined based on qualifications ​
• Working knowledge of networking fundamentals including TCP/IP, DNS, TLS/certificates, firewalls, port requirements, and load balancing sufficient to troubleshoot application connectivity issues
• Advanced SQL proficiency and scripting experience in Python, PowerShell, or similar languages
• Working knowledge of change control and structured release management
• Experience in a regulated environment including GxP or 21 CFR Part 11 preferred
• Experience with network diagnostic tooling such as Wireshark, packet captures, or traceroute preferred
• Familiarity with CI/CD practices for configuration promotion and experience supporting systems across US and EU time zones a plus

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$94,000.00 - $179,500.00