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Vertex Pharmaceuticals

Develops therapies for serious genetic diseases

Senior Director, Solution Architect – Core Technology - Core Technology Architect

IT OperationsConfirmed live in the last 24 hours
Full-timeBoston, MA, USA

About the Job

Requirements

  • 12–15+ years of experience in IT infrastructure and workplace technologies.
  • Proven experience in solution architecture or enterprise architecture leadership roles.
  • Experience operating in complex, global enterprise environments.
  • Demonstrated success working across multiple infrastructure domains simultaneously.
  • Demonstrated ability to lead through influence in a federated organization.
  • Strong executive presence with communication and stakeholder management skills.
  • Ability to translate complex technical concepts into clear business-aligned recommendations.
  • Proven ability to balance strategic architecture with pragmatic execution.
  • Experience collaborating with global vendors, strategic partners, and managed service providers.
  • Knowledge of Azure architecture and cloud services, AWS cloud environments, the Microsoft 365 ecosystem, Microsoft Teams, Exchange, SharePoint, Microsoft Copilot, Azure AI, enterprise networking and infrastructure, and SD-WAN.
  • Experience aligning security architecture and co-architecting cybersecurity technologies, including identity, endpoint protection, network security, zero trust, and cloud security solutions.
  • Knowledge of data center and hybrid hosting environments.
  • Knowledge of end-user computing across Windows, Mac, and mobility platforms.
  • Knowledge of collaboration technologies, including Zoom and Teams Rooms.
  • Knowledge of ServiceNow and IT service management platforms.
  • Knowledge of architecture governance and standards development, reference architecture, integration pattern design, technology lifecycle management, and rationalization.

Responsibilities

  • Define and drive end-to-end solution architecture across Core Technology domains, including cloud platforms, Microsoft 365, enterprise network services, data center and hybrid hosting environments, end-user computing, workplace collaboration technologies, and IT service management platforms.
  • Partner with Information Security to co-architect and integrate cybersecurity platforms and controls across cloud, network, workplace, collaboration, and end-user computing domains, aligning them with Core Technology reference architecture, operational models, and enterprise risk requirements.
  • Partner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and security architecture across the enterprise.
  • Create reference architectures, design standards, and integration patterns across technology domains.
  • Eliminate silos and ensure interoperability across Core Technology services.
  • Drive scalable and sustainable architectural approaches that support global business needs.
  • Lead Core Technology architecture strategy to enable enterprise AI capabilities, including Microsoft Copilot, Microsoft 365, and Azure AI.
  • Ensure AI-related solutions are securely integrated across infrastructure layers.
  • Partner with Security and Data teams to align AI architecture with governance, privacy, and regulatory expectations.
  • Help shape a seamless and secure digital workplace experience for employees globally.
  • Establish architecture governance processes for design reviews, technology standards, and exception management.
  • Serve as the central point of accountability for cross-domain architectural decisions.
  • Ensure alignment with GxP, regulatory, compliance, and security requirements.
  • Drive lifecycle management, rationalization, and modernization of Core Technology platforms.
  • Operate as a peer to Directors across Network, Cloud, end-user computing, Collaboration, and related domains.
  • Serve as the primary Core Technology architecture partner to Information Security, driving joint architecture reviews, technology evaluations, integration decisions, and long-term platform strategy.
  • Influence technical direction across a federated organization without direct authority.
  • Partner with Information Security, Data Services, and Application teams to define and maintain a unified infrastructure, collaboration, and security architecture strategy and roadmap.
  • Act as a trusted advisor to senior DTE leadership on technology strategy, investments, and roadmap decisions.
  • Balance strategic vision with practical execution to accelerate business value.
  • Shape architecture strategy in partnership with key vendors and service providers, including Microsoft, Cisco, Palo Alto, Verizon, AT&T, Zoom, ServiceNow, Accenture, Lenovo, Dell, and Apple.
  • Ensure third-party solutions align with enterprise architecture standards and long-term technology strategy.
  • Support effective vendor collaboration to deliver secure, compliant, and high-performing services.
  • Ensure solutions are designed for operability in partnership with outsourced operations teams.
  • Drive consistency between architecture and service delivery models, including Service Desk and Deskside Support.
  • Improve end-user experience, supportability, and reliability through cohesive technical design.
  • Strengthen alignment between architecture, engineering, and operations.

Desired Qualifications

  • Experience enabling enterprise AI solutions in a regulated environment.
  • Familiarity with digital workplace transformation initiatives.
  • Background in hybrid infrastructure and global collaboration ecosystems.
  • Knowledge of service delivery operating models and managed services integration.
  • Experience improving interoperability across infrastructure, workplace, and support platforms.
  • Strong understanding of compliance, governance, and secure-by-design architecture principles.
  • Experience in GxP-regulated environments such as biotechnology, pharmaceuticals, or healthcare.

About the Company

Vertex Pharmaceuticals

Develops therapies for serious genetic diseases

Vertex Pharmaceuticals develops medicines for serious diseases, with a focus on cystic fibrosis. It conducts extensive research and partners with other biotech firms to discover and develop new therapies, including ex vivo engineered cell treatments. Its products, such as ivacaftor, treat cystic fibrosis and other therapies undergo clinical testing to expand the pipeline. Revenue comes from selling approved drugs and from licensing and collaboration agreements. The company distinguishes itself through deep R&D investment, strategic partnerships, and a global reach aimed at addressing unmet medical needs. The overall goal is to bring effective new drugs to patients worldwide and improve outcomes and quality of life.

Company size
5,001-10,000
Company stage
IPO
Headquarters
Boston, MA
Founded
1989

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