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Dayhoff Labs

AI-driven molecular design and simulation

Experimental Systems Engineer - Analytical Chemistry

Physical SciencesConfirmed live in the last 24 hours
Full-timeNo salary listedIn-person

About the Job

Requirements

  • Experience building experimental hardware or analytical setups hands-on.
  • Comfort with liquid handling systems, including pumps, valves, tubing, flow cells, and troubleshooting leaks, bubbles, fouling, and drift.
  • Experience with at least some analytical chemistry methods, such as spectroscopy, chromatography, mass spectrometry, nuclear magnetic resonance, or electrochemical sensing.
  • Practical Python skills for data acquisition, analysis, plotting, and automation.
  • Willingness to work across wet-lab activities, instrument manuals, notebooks, code, and physical prototyping.
  • Good judgment in determining when a measurement is meaningful or misleading and when a setup needs rebuilding.

Responsibilities

  • Design and build prototype systems for monitoring aqueous chemical reaction networks in real time.
  • Work with small continuously stirred tank reactors, flow reactors, microfluidic devices, pumps, valves, tubing, flow cells, and autosamplers.
  • Evaluate analytical technologies including Raman spectroscopy, ultraviolet-visible spectroscopy, fluorescence, infrared spectroscopy, nuclear magnetic resonance, liquid chromatography-mass spectrometry, high-performance liquid chromatography, electrochemical sensing, and low-cost process probes.
  • Build Python-based tools for data acquisition, instrument control, signal processing, and visualization.
  • Combine continuous measurements with sampled analytical data to reconstruct the time evolution of chemical mixtures.
  • Work with chemists, enzymologists, computational scientists, and machine learning engineers to turn messy signals into useful data.

Desired Qualifications

  • Experience with Raman, Fourier-transform infrared spectroscopy, ultraviolet-visible spectroscopy, fluorescence, online nuclear magnetic resonance, liquid chromatography-mass spectrometry, high-performance liquid chromatography, or mass spectrometry workflows.
  • Experience with lab automation tools such as Arduino, Raspberry Pi, LabJack, National Instruments data acquisition, serial instrument control, autosamplers, or custom data logging.
  • Experience building fast prototypes in a startup, academic lab, instrument company, or hardware-heavy research environment.

About the Company

Dayhoff Labs

AI-driven molecular design and simulation

Dayhoff Labs develops AI models and computational platforms to solve complex problems in chemistry, biochemistry, and synthetic biology. Its tools help researchers design, optimize, and simulate molecules such as enzymes and catalysts, enabling faster discovery and more sustainable chemical processes. By combining machine learning, computational chemistry, and laboratory work, it offers machine-assisted workflows that integrate experimental data and collaboration with researchers, with a strong emphasis on open science. The company aims to shorten discovery timelines, reduce costs and environmental impact, and broaden access to AI-powered molecular design for academia and industry.

Company size
11-50
Company stage
Not listed
Total funding
Not listed
Headquarters
Boston, MA
Founded
2022

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