Registered Nurse - Oncology Chemotherapy Treatment Unit

As a Chemotherapy Infusion RN, you’ll do more than deliver treatment. You’ll make a lasting impact during some of the most critical moments in a patient’s life.

If you’ve been looking for a role where your work truly matters, this is one of those places.

Why this team feels different

You’ll join a team where you are supported, valued, and truly part of something.  Leaders are approachable, and teammates show up for one another, because no one does this work alone.

Here, you’re encouraged to grow, speak up, and bring your full self to the team.

The work you’ll do

In our 53-chair outpatient oncology treatment unit (Gonda 10E), you will:

• Administer chemotherapy, immunotherapy, and advanced cancer therapies
• Support patients through education, therapeutic communication, and emotional care
• Collaborate with a multidisciplinary team on innovative treatments and research  

You’ll work with ports, PICC lines, and IV placement while building meaningful relationships with patients throughout their care.

It’s fast-paced, complex, and deeply meaningful work.  

A place to grow

This team supports you in practicing at the top of your scope while continuing to build your expertise.

You’ll have opportunities to precept, develop leadership skills, and grow your confidence and autonomy in daily practice.

You may be a great fit if you:

• Want work that feels purposeful, not routine
• Value being part of a supportive, team-oriented environment  
• Take pride in being both highly skilled and deeply compassionate

Position Details

The primary role of the RN in this position is administration of chemotherapeutic agents and patient education in the outpatient setting.

Watch what it’s like to be a Chemotherapy Infusion RN at Mayo Clinic

Orientation and Growth

We are committed to helping you feel supported, prepared, and confident as you build your oncology nursing practice.

Your orientation includes:

• 12+ hours of structured chemotherapy education
• 12 hours of cancer core knowledge
• Three months of guided, hands-on learning  

You’ll work side-by-side with a preceptor to build IV skills, strengthen critical thinking, and grow into the role step by step.

As cancer care continues to evolve, we prepare our nurses not only for today’s patients, but for the therapies shaping the future of oncology care.

It’s also an exciting time to join our team, with a 15-chair expansion planned for early 2027.

The registered nurse (RN) is accountable for:

• Coordination of nursing care, including direct patient care, patient/family education and transitions of care.  
• Supporting professional nursing practice across practice settings and across the continuum of care to meet the needs of the patient and family.  
• Functioning within the Mayo Clinic Nursing Professional Practice Model, which includes accountability for planning, implementing, evaluating and communicating all phases of nursing care for assigned patients. The ANA Nursing: Scope and Standards of Practice provide a basis for the practice of the RN. 
• Providing leadership through activities such as preceptor role, informal and formal leadership roles, and quality improvement efforts.  
• Delegating patient care according to skill level, experience, patient acuity, fiscal accountability and availability of resources.  
• Possessing excellent communication skills; is skillful in mentoring and teaching; and may participate on committees or projects.  
• A subset of employees may be required to drive their personal vehicle as a part of the responsibility of their role.  

For New Graduate Nurses: Please apply through the Nurse Residency Program posting, which is specifically designed to support new graduate RNs. Visit the Nurse Residency webpage for program details including current and upcoming application windows. Within the Nurse Residency application process, you may indicate work units and specialties of interest. If selected to move forward, you will meet with a Nursing Placement Coordinator who will help you explore Mayo Clinic opportunities that are best aligned with your current and future professional goals. Together, we’ll identify a work area that provides an excellent foundation for your nursing career.

The registered nurse (RN) is accountable for the coordination of nursing care, including direct patient care, patient/family education and transitions of care. The RN supports professional nursing practice across practice settings and across the continuum of care to meet the needs of the patient and family. The RN will function within the Mayo Clinic Nursing Professional Practice Model, which includes accountability for planning, implementing, evaluating and communicating all phases of nursing care for assigned patients. The ANA Nursing: Scope and Standards of Practice provide a basis for the practice of the RN. The RN provides leadership through activities such as preceptor role, informal and formal leadership roles, and quality improvement efforts. The RN delegates patient care according to skill level, experience, patient acuity, fiscal accountability and availability of resources. The RN possesses excellent communication skills; is skillful in mentoring and teaching; and may participate on committees or projects. A subset of employees may be required to drive their personal vehicle as a part of the responsibility of their role. 

This role is eligible for TN sponsorship. Holders of F1 status eligible for post-completion OPT are welcome to apply. This role is NOT eligible to participate in the F-1 STEM OPT extension program. Successful sponsorship will require state licensure and completion of the VisaScreen or equivalent certification.

Graduate of a nursing program, as recognized by the Accreditation Commission for Education in Nursing (ACEN), Commission on Collegiate Nursing Education (CCNE), National League for Nursing Commission for Nursing Education Accreditation (NLN CNEA). One year of RN experience required.

All entry-level associate degree registered nurses with a RN start date of April 1, 2020 and after must provide documented evidence of program completion of the baccalaureate degree in nursing from an accredited nursing program within five years from the last day of the month of the RN start date.

All entry-level associate degree registered nurses with a RN start date prior to April 1, 2020 must provide documented evidence of program completion of the baccalaureate degree in nursing from an accredited nursing program as stipulated by the degree requirement program in place at time of hire.

Additional Qualifications:

Excellent communication skills (verbal and written). Experience working in a team environment. Computer skills required, prior experience with electronic medical record systems preferred. Ability to adapt to unpredictable situations within the work setting. Demonstrated leadership, effective communicator, and excellent critical thinking skills.

Internal applicants are required to attach their three most recent performance appraisals.

License and Certification (Must obtain prior to start date): 

Current RN license by applicable state requirements.

BLS (Basic Life Support) must be valid for 90 days post start date; acceptable certifications include: American Heart Association (AHA)/ Heartcode® BLS, Military Training Network, Red Cross (CPR/AED for Professional Rescuers and Health Care Providers).

Additional state licensure(s) and/or specialty certification/training as required by the work area.

Compensation Detail: The pay for this role is $35.84 - $58.84. Mayo Clinic has an innovative nursing compensation model that rewards experience, education, and dedication to the organization. Combined with our competitive tuition reimbursement program, the compensation approach empowers nurses to grow professionally and maximize their earning potential.