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EMBL

Intergovernmental European life sciences research organization

Functional Genomics Data Project Lead

Data ManagementPosted on Nov 10
Full-timeHinxton, Saffron Walden, UK£4.4k /mo

About the Job

Requirements

  • A degree in bioinformatics, computational biology, molecular biology, genomics or a related discipline, or equivalent relevant professional experience.
  • A strong understanding of modern functional genomics assays and their data requirements, with substantial practical expertise in one or more relevant technologies, such as bulk and single-cell transcriptomics, spatial approaches, or assays of chromatin accessibility and gene regulation.
  • Sound knowledge of experimental design, biological and technical replication, batch effects and other sources of bias, with the scientific judgement to evaluate analytical methods, assess data quality and identify limitations.
  • Strong hands-on experience developing, validating and maintaining Nextflow workflows.
  • Programming experience in Python and/or R, confidence in Linux environments, and practical knowledge of version control, containers and automated testing for reproducible analysis.
  • Experience working with structured metadata, controlled vocabularies or ontologies, and an understanding of data provenance, interoperability and reproducibility.
  • Experience developing scientific or technical roadmaps and delivering complex projects or services, including prioritisation, resource planning and risk management.
  • Strong communication and stakeholder management skills, with experience negotiating requirements, managing dependencies and coordinating delivery across teams or organisations.

Responsibilities

  • Lead and develop the bioinformatics and curation team, with formal line management responsibilities including objectives, appraisals, performance management, career development and recruitment.
  • Develop the scientific data strategy and roadmap with the Team Leader and Technical Lead, translating scientific needs and emerging technologies into priorities and achievable delivery plans.
  • Own standards for submitted data, metadata and curation, including experimental descriptions and sample relationships. Define additional quality controls and suitability criteria for downstream analysis, visualisation and reuse.
  • Lead the development, validation and improvement of reproducible Nextflow workflows. Ensure analytical methods suit the experimental design and that outputs are documented, versioned and traceable to their source data and reference annotations.
  • Plan and coordinate work across team members, balancing service operation with development. Monitor community demand, backlogs and turnaround times, and manage capacity, milestones, dependencies and risks to meet agreed service targets. Resolve issues within your remit and escalate resource constraints where necessary.
  • Act as the principal scientific liaison with other EMBL-EBI teams and partners, including ENA, Ensembl, UniProt and Open Targets, agreeing requirements and coordinating dependencies for data exchange and reuse.
  • Manage requirements from external data consumers and collaborators, negotiate priorities and scope, and agree data formats, release expectations and communication of changes.
  • Contribute selected hands-on work in Nextflow development, scientific validation, benchmarking or complex data investigations, while providing scientific guidance to colleagues.

Desired Qualifications

  • Line management experience, including setting objectives, supporting development, providing constructive feedback and addressing performance or workload issues.
  • Experience designing or applying JSON Schema for metadata or data validation.
  • Experience with relational or document databases, including data modelling and querying.
  • Experience operating a public biological data resource, including submission, scientific curation, processing or data release workflows.
  • Experience processing large datasets on high-performance computing or cloud infrastructure, and familiarity with nf-core.
  • Experience with biological data standards, APIs or integration between archives, data portals and knowledgebases.

About the Company

EMBL

Intergovernmental European life sciences research organization

EMBL is Europe’s flagship life sciences laboratory that conducts basic molecular biology research and runs a wide network of over 80 independent research groups across six sites (Heidelberg, Barcelona, Hamburg, Grenoble, Rome, and EMBL-EBI Hinxton). It also provides scientific services to member states, trains scientists and students, develops new instruments and methods for the life sciences, and engages in technology transfer to share discoveries. Its work is carried out by an intergovernmental organization dedicated to advancing European life science research. EMBL supports researchers through access to facilities and services, training programs, and collaborative projects, while coordinating and integrating resources across Europe and fostering tech transfer. Its goal is to advance fundamental science, enable scientific progress across Europe, and strengthen the ecosystem of life science research and innovation through collaboration, training, and shared tools.

Company size
1,001-5,000
Company stage
Not listed
Total funding
Not listed
Headquarters
Spain
Founded
1974

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