Full-Time

Senior Scientist

Antibody Engineering

Posted on 5/8/2024

Flagship Pioneering

Flagship Pioneering

501-1,000 employees

Biotechnology firm creating health and sustainability solutions

Venture Capital

Senior

Cambridge, MA, USA

Required Skills
Communications
Requirements
  • PhD with 5+ years of experience in protein engineering, synthetic biology, molecular biology, biochemistry, or related field
  • Prior industry experience in drug discovery or preclinical development with a focus on antibody development preferred
  • Deep technical expertise with phage display systems focusing on the generation of very high library diversity
  • Proficiency in molecular biology techniques including Golden Gate, Gibson assembly, construction of mutational libraries, and NGS sample preparation
  • Experience with standard/phage-based ELISA and other methods of binding characterization
  • Proven expertise in discovery campaign design and optimization and interpretation of results from diverse assays and NGS readouts
  • Familiarity with high throughput automation of display workflows
  • Familiarity with the drug development process from discovery to IND
  • Excellent communication skills and ability to convey complex messages across multidisciplinary teams
  • Scientific excellence, execution rigor, creative resourcefulness, critical thinking, attention to detail, organization skills, and proven track record of achievement
Responsibilities
  • Design and execute phage display campaigns
  • Collaborate with the Platform Discovery and Engineering team to develop scientific strategy
  • Drive hit-to-lead process and optimize lead candidates
  • Develop strategy for high-throughput antibody discovery and library-based engineering
  • Contribute to therapeutic discovery program teams
  • Collaborate with Computational and Translational Sciences teams
  • Develop and validate ligand-binding and cell-based assays
  • Support protection, creation, and expansion of company's intellectual property
  • Prepare and present data packages for program progression and decision-making

Flagship Pioneering fosters a culture of groundbreaking advancements in biotechnology, emphasizing an ecosystem approach that synergizes human health and sustainability. Their business model not only focuses on creating transformative products but also incubates leading companies like Moderna and Indigo Agriculture, positioning them at the forefront of scientific innovation and industry leadership. This approach offers employees a unique opportunity to be part of a pioneering team that drives real-world impacts across multiple sectors.

Company Stage

N/A

Total Funding

$6.4B

Headquarters

Cambridge, Massachusetts

Founded

2000

Growth & Insights
Headcount

6 month growth

9%

1 year growth

20%

2 year growth

53%