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Ohr

Cell-free biomanufacturing for critical chemicals

Process and Synthetic Chemist - Mining & Metals

Physical SciencesConfirmed live in the last 24 hours
Full-time

About the Job

Requirements

  • A PhD in organic or process chemistry with at least 3 years of experience beyond the degree, or a BS/MS with at least 8 years of industrial route-development experience.
  • Hands-on depth in phenolic, aromatic, and heterocyclic synthesis, with a broad working repertoire of classical bond-forming reactions.
  • Experience with catalytic hydrogenation and pressure reactor operation.
  • A record of delivering 100 g of characterized material against a date, rather than only milligram-scale proof of reaction feasibility.
  • Experience with cost modeling per kilogram at the route-selection stage, including a specific example.
  • A habit of treating hazards as an input to route choice rather than only as a downstream control problem.
  • Sufficient structural characterization expertise to interpret NMR, HPLC, GC, and MS.
  • Candidates must be a U.S. citizen or national, lawful permanent resident, or a protected individual under 8 U.S.C. § 1324b(a)(3).

Responsibilities

  • Run synthesis campaigns sized to deliver 100 g of characterized material across heterocyclic, aromatic, chelating-ligand, and phenolic condensation chemistry.
  • Select synthesis routes based on delivered cost per kilogram, assessing step count, step type, yield, and reagent choice, and defend or overturn route calls based on modeled cost.
  • Own route-related hazard assessments, including reaction calorimetry and thermal characterization of phenolic cure, quench design with cooling and acid-gas handling for corrosive workups, and handling plans for carcinogenic reagents used at scale.
  • Propose and triage new candidates on the company’s platform chemistries, including evaluating their cost before bench work.
  • Assess which applications the binding chemistry can address, including selectivity for gallium, manganese, magnesium, nickel, and cobalt in relevant refining and processing circuits.
  • Sequence campaigns that converge on the same quarter and defend the sequence to dependent product lines.
  • Operate and specify bench equipment, including jacketed 1–20 L reactors with dosing and temperature control, a pressure and hydrogenation reactor, rotary evaporation, column chromatography, reaction calorimetry, and a dedicated hood for highly hazardous reagents.
  • Write process documentation that enables another chemist to repeat each campaign.

Desired Qualifications

  • Experience with heterocyclic chemistry.
  • Experience with condensation polymer chemistry and molecular-weight control on a phenolic oligomer.
  • Experience with metal extraction chemistry, including chelating ligands, solvent-extraction reagents, flotation collectors, or ion-exchange resin synthesis.
  • Experience with reaction calorimetry and runaway-exotherm characterization.
  • Experience working within procurement controls, including controls for documented explosives precursors.
  • Experience with flow chemistry, particularly for exothermic or corrosive steps.

About the Company

Ohr

Cell-free biomanufacturing for critical chemicals

OHR designs and manufactures critical chemicals using Creationary Chemistry, starting from simple, abundant feedstocks rather than crude oil, with modular, local production. It combines engineered enzymes with primordial chemistry in a cell-free system to build carbon chains with high selectivity, creating privileged intermediates that become end products without living cells or toxic waste. This approach eliminates traditional extraction, separation, and refining steps and uses a single platform to access energetics, propellants, binders, and advanced materials across defense, mining, and propulsion. The goal is industrial sovereignty and independence, enabling distributed production near local feedstocks under a build-own-operate model to bypass concentrated supply chains.

Company size
11-50
Company stage
Not listed
Total funding
Not listed
Headquarters
San Diego, CA
Founded
2024

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