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Kepler

AI agent platform for bioinformatics workflows

Machine Learning Engineer

Applied Machine LearningConfirmed live in the last 24 hours
Full-timeNew York, NY, USA$200k - $280k /yr

About the Job

Requirements

  • At least 5 years of experience building production software.
  • Experience shipping machine learning systems to production, including fine-tuning, agents, retrieval, or structured extraction.
  • Ability to build evaluation and measurement systems before features and validate improvements with data.
  • Strong general engineering fundamentals; Rust experience is not required.
  • Ability to work across fine-tuning workflows and orchestration code.
  • Experience with software production quality, failure modes, and correctness.

Responsibilities

  • Own the models used inside Kepler's AI research platform, including model selection, model routing, fine-tuning, evaluation, and extraction systems.
  • Fine-tune models for high-volume extraction tasks and compare accuracy, cost, and latency against frontier models.
  • Build end-to-end evaluation harnesses for agent research runs and integrate them into continuous integration to catch regressions.
  • Redesign model routing across workflows, selecting models for reasoning, extraction, and verification and validating results with evaluations.
  • Improve workflow success rates through tooling, verification rules, context changes, fine-tuning, or model selection.
  • Own systems end-to-end and take ownership of functional areas, platform extensions, and architecture as infrastructure scales.

About the Company

Kepler

AI agent platform for bioinformatics workflows

Kepler AI builds an AI agent platform for bioinformatics research and workflow automation. It lets research teams, biotech firms, and pharmaceutical companies ask complex questions in plain English without writing code, and it connects to large datasets to speed up drug discovery. The platform supports data analysis, experiment planning, and literature reviews by running AI agent-based queries across integrated data sources, unifying scattered databases to help identify drug candidates more efficiently. A notable collaboration with TileDB and Tahoe Therapeutics produced TahoeDive, which adds Tahoe-100M single-cell perturbation data into Kepler AI’s platform. The company’s goal is to increase scientific productivity and accuracy in life sciences R&D and to accelerate the path from data to actionable insights in drug discovery.

Company size
11-50
Company stage
Not listed
Total funding
Not listed
Headquarters
New York City, New York
Founded
2025

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