Upstream Process Development Scientist

Job Description

Position Overview:

Our Eurofins PSS team is seeking an Upstream Scientist to work onsite supporting our client's upstream process development activities related to the production of sterile, injectable lentiviral vector (LVV)-based gene therapy products.  The successful candidate will help support the execution and optimization of LVV production protocols, maintenance of mammalian suspension cell culture systems, process robustness, and yield-improvement studies. This role partners closely with cross-functional teams across the CMC project teams to support all upstream operations for the client's program. This is an excellent opportunity for a detail-oriented scientist to contribute directly to the development of novel gene therapy products from an established, hands-on upstream role.

Job Responsibilities:

• Execute LVV production protocols using shake flasks and benchtop bioreactors to support ongoing process development and characterization studies.
• Support routine maintenance of suspension cell cultures, applying strong aseptic technique and sterile workflow practices to preserve culture health and integrity.
• Collaborate with cross-functional teams to coordinate analytical testing, exchange materials, share technical observations, and align on project timelines.
• Maintain lab stocks, supplies, and equipment specific to the upstream team to support daily operations.
• Document process data in electronic lab notebook and shared databases and communicate key observations in team meetings.

Qualifications

Basic Minimum Qualifications:

• B.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 1 year of relevant industry experience OR M.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 6 months of relevant industry experience.
• Proficient in mammalian suspension cell culture operations, including execution of established production protocols for routine culture maintenance and shake flask seed train expansion.
• Strong aseptic technique, with hands-on experience working within a biosafety cabinet (BSC) to maintain sterile, contamination-free workflows.
• Experience with buffer and media preparation to support ongoing cell culture operations.
• Experience documenting process results in electronic lab notebooks and effectively communicating experimental observations to management and cross-functional team.
• Meticulous attention to detail in sample tracking, experiment execution, data recording, and laboratory documentation.
• Ability to set priorities and multi-task activities to effectively manage workflows and drive deliverables to completion.
• Strong team orientation, with excellent organizational skills, self-motivation, and a positive attitude.
• Strong communication skills, with the ability to clearly communicate experimental results and observations.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Preferred Qualifications:

• Previous experience with viral vector, cell therapy, gene therapy, or related biologics process development.
• Hands-on experience operating and maintaining laboratory equipment, including shake flasks, benchtop bioreactor systems, peristaltic pumps, and tube welders.
• Experience performing cell banking activities to support consistent, well-characterized starting material for upstream production.
• Familiar with gene delivery techniques such as transient transfection.

Additional Information

This role is a full-time, permanent position Monday-Friday 8am-5pm withoccasional weekend/holiday work, as well as periodic work outside of working hours. . Candidates currently located within commutable distance to Boston, MA are encouraged to apply.

Excellent full-time benefits include:

• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Eligibility for yearly goal-based bonus & merit-based increases
• Compensation: $32.00-$36.00 per hour based on education and relatable industry experience.

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Compensation: 32 to 36 (USD) (HOURLY)