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Ellison Institute of Technology

Interdisciplinary R&D translating science into products

Scientist: Cell-Based Screening - Photosynthesis Pathway and Enzyme Engineering

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeOxford, UKIn-person

About the Job

Requirements

  • A PhD in Plant Biology, Plant Physiology, Photosynthesis, Synthetic Biology, Metabolic Engineering, Molecular Biology, Biochemistry, or a related discipline is required.
  • A strong research background with expertise in one or more areas relevant to the role is required.
  • Experience developing or applying cell-based methods to measure carbon fixation, photosynthetic activity, and/or metabolic performance is required.
  • Experience engineering photosynthesis or carbon fixation is required.
  • Experience in plant metabolic engineering, enzyme engineering, or synthetic biology is required.
  • Experience designing, generating, or screening enzyme variant libraries is required.
  • Experience with transient and stable genetic engineering in plant cell cultures, including targeted gene knockout, gene insertion, and CRISPR-based genome editing, is required.

Responsibilities

  • Lead development of a plant cell-based screening platform to assess carbon fixation and other physiological responses in suspension cultures.
  • Develop and apply quantitative methods to measure carbon fixation rates in plant cell suspensions.
  • Use the screening platform to identify improved photosynthesis enzyme variants.
  • Use the screening platform to assess engineered metabolic pathways designed to enhance photosynthesis.
  • Lead genetic engineering experiments in plant cell cultures, including targeted gene knockouts, gene insertions, and CRISPR-based genome editing.
  • Apply iterative design-build-test-learn cycles to develop and refine engineering strategies.
  • Advance promising enzyme variants and pathway designs into whole plants for functional validation.
  • Drive rigorous experimental design, execution, and data interpretation to ensure robust and reproducible scientific outcomes.
  • Deliver research progress through stage-gated milestones.
  • Collaborate with cross-functional teams to incorporate cutting-edge research techniques into experiments.
  • Present scientific work at EIT seminars and external meetings, including contributing to discussions about developments in the field.
  • Assist with mentoring other members of the research group where appropriate.
  • Assist in translating scientific results into commercial opportunities consistent with EIT's humane endeavours.
  • Recognize and act on opportunities to create intellectual property, cooperate in patent protection, and support impact delivery.
  • Conduct research ethically and in compliance with EIT policy, regulatory guidance, and best scientific practice.

Desired Qualifications

  • Experience using bioreactor and microculture platforms for plant cell cultivation, physiological monitoring, and experimental workflows.
  • Experience with plant gas-exchange analysis and chlorophyll fluorescence measurements in plant cells or tissues.
  • Knowledge of enzyme biochemistry, assembly, and regulation.
  • Experience generating and preparing biological samples for transcriptomic, metabolomic, and proteomic analyses.
  • Experience with laboratory automation, robotics, and high-throughput experimental workflows.

About the Company

Ellison Institute of Technology

Interdisciplinary R&D translating science into products

The Ellison Institute of Technology unites science, engineering, policy, and entrepreneurship to tackle big global problems through four focus areas: Health, Medical Science & Generative Biology; Food Security & Sustainable Agriculture; Clean Energy Generation & Storage; and Artificial Intelligence & Robotics. It translates scientific discovery into commercial products and sustainable companies, reinvesting profits to fund more research; a key project is the GPAS bioinformatics platform for rapid pathogen analysis to help prevent pandemics. The institute differentiates itself through a deep alliance with the University of Oxford, an alliance faculty model that allows researchers to work across both institutions, and patient capital commitments to fund high-risk, high-reward research. Its goal is to solve global challenges by turning scientific breakthroughs into market-ready solutions and sustainable enterprises.

Company size
201-500
Company stage
Not listed
Total funding
Not listed
Headquarters
Oxford, United Kingdom
Founded
2023

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