N

Novartis

Global pharmaceutical company delivering science-based innovations

Research Scientist 1 or 2 - Oligonucleotide Chemistry

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeCambridge, MA, USA

About the Job

Requirements

  • A Bachelor of Science or Master of Science in Chemistry or a related scientific discipline is required.
  • One to three years of laboratory experience in academic or industrial research environments is required.
  • Hands-on experience with automated solid-phase synthesizers and therapeutic oligonucleotide synthesis workflows is required.
  • Proficiency in oligonucleotide purification, characterization, and analysis using chromatography and mass spectrometry techniques is required.
  • Understanding of RNA therapeutics and their application in biological systems is required.
  • Strong collaboration, adaptability, and self-motivation in a fast-paced scientific environment are required.

Responsibilities

  • Execute solid-phase synthesis of research-scale oligonucleotides using advanced automated DNA and RNA synthesizers.
  • Purify, desalt, and characterize oligonucleotides using chromatographic and mass spectrometry techniques.
  • Develop and optimize synthesis, purification, and analytical methods to improve performance and reproducibility.
  • Operate, maintain, and troubleshoot laboratory instrumentation supporting oligonucleotide production and analysis.
  • Prepare and maintain standard operating procedures to support high-quality and consistent laboratory practices.
  • Organize, analyze, and document experimental results using electronic laboratory notebook systems.
  • Contribute effectively within a collaborative research environment focused on therapeutic innovation.

Desired Qualifications

  • Experience supporting oligonucleotide process development, optimization, or technology innovation initiatives.
  • Scientific communication skills to present findings to multidisciplinary teams.

About the Company

Novartis

Global pharmaceutical company delivering science-based innovations

Novartis is a global pharmaceutical company that uses science-based innovations to develop treatments and improve patient outcomes worldwide. Its products are medicines developed through research and development to address various diseases, aiming to reach nearly 1 billion people. The company differentiates itself by large-scale investment in R&D, a global presence with a diverse workforce, and a clear mission to Reimagine Medicine, focusing on meeting the changing needs of patients. Its goal is to improve quality of life and extend life expectancy by delivering meaningful therapies through its research and development efforts.

Company size
10,001+
Company stage
IPO
Headquarters
Basel, Switzerland
Founded
1970

Recently Posted Jobs

Explore more opportunities at Novartis

See more jobs