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GRAIL

Blood-based cancer detection via sequencing tests

Associate Scientist 2 - Assay R&D

Translational Research & Bench BiologyPosted on Nov 12
Full-timeDurham, NC, USA

About the Job

Requirements

  • A Bachelor's degree in Biology, Chemistry, Biochemistry, or a related scientific discipline with 2–5 years of relevant experience, or a Master's degree in a related field with 0–2 years of relevant experience.
  • Demonstrate knowledge of applicable regulatory standards appropriate to the position’s complexity and scope, including GMP quality management systems such as ISO 13485 and operations in regulated medical-device environments, including IVDD, IVDR, FDA 21 CFR 800 series, and FDA 21 CFR Part 11.
  • Work in a laboratory environment with exposure to biological, chemical, or hazardous materials, using required personal protective equipment including lab coats, gloves, and safety glasses.
  • Perform prolonged standing, pipetting, and handling of laboratory materials; occasional evening or weekend work may be required to meet project demands.

Responsibilities

  • Perform established laboratory experiments using professional methods in molecular biology, including RNA isolation, genomic DNA isolation, cDNA preparation, cloning, fermentation, protein expression, and purification, with increasing independence and accuracy.
  • Prepare, process, and analyze samples, reagents, buffers, and media for experimental workflows, applying professional judgment to ensure precision, proper documentation, and procedural compliance.
  • Collect, interpret, and document experimental data in laboratory notebooks or electronic systems using data-management practices that support reproducibility and scientific integrity.
  • Operate, maintain, and routinely troubleshoot laboratory equipment, identifying issues that require escalation and ensuring instruments remain ready for scientific work.
  • Assist in refining laboratory protocols or methods by providing observations on workflow efficiency, data quality, and opportunities for procedural improvement.
  • Contribute to technical reports, data summaries, protocol drafts, and quantitative analyses to support scientific communication and project decision-making.
  • Adhere to safety, regulatory, and quality standards when handling chemical and biological materials and help maintain a professional laboratory environment.
  • Support laboratory operations through inventory oversight, material organization, supply coordination, and continuous process improvement.
  • Provide informal guidance and technical support to junior laboratory staff by sharing knowledge, reinforcing documentation standards, and modeling effective laboratory practices.
  • Adapt responsibilities as business needs and strategic priorities evolve, including taking on additional responsibilities, participating in cross-functional projects, adopting new technologies or processes, supporting other departments during periods of high demand, and contributing to special projects or temporary assignments.

Desired Qualifications

  • Demonstrate technical proficiency in standard laboratory techniques and equipment operation.
  • Analyze data, identify issues, and communicate findings clearly.
  • Use laboratory documentation systems, data-management tools, and reporting processes.
  • Apply laboratory safety practices, compliance requirements, and quality standards.

About the Company

GRAIL

Blood-based cancer detection via sequencing tests

GRAIL develops blood-based cancer tests that aim to detect cancer at its earliest stages. The tests use high-intensity sequencing to analyze large amounts of tumor genome data from a blood sample and apply advanced algorithms and deep learning to identify signals indicating cancer. Revenue comes from selling these tests to healthcare providers and research institutions, with potential expansion to direct-to-consumer sales in the future. Compared with others, GRAIL combines extensive sequencing data with clinical studies and sophisticated analytics to provide actionable cancer-detection results, focusing on early diagnosis. The company’s goal is to lower global cancer mortality by catching the disease early when treatment is more effective.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Menlo Park, CA
Founded
2016

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