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Twist Bioscience

Produces synthetic DNA for research.

Director, Security and Compliance

Security Governance, Risk & ComplianceConfirmed live in the last 24 hours
Full-timeSouth San Francisco, CA, USA

About the Job

Requirements

  • A Bachelor of Science or Master of Science degree in Computer Science, Information Systems, Cybersecurity, or Business, or equivalent practical experience.
  • At least 10 years of experience in information security, risk management, or compliance roles, including at least 5 years in a dedicated leadership or managerial capacity.
  • Strong familiarity with AWS or similar cloud environments and modern compliance automation platforms such as Vanta, Drata, or Anecdotes.
  • Proven experience achieving and maintaining certifications such as SOC 2 Type II or ISO 27001 from the ground up.
  • Strong verbal and written communication skills, with the ability to discuss log management with engineers and explain corporate risk to a non-technical board.

Responsibilities

  • Lead the strategy, implementation, and continuous monitoring of core security frameworks relevant to the business, including SOC 2, ISO 27001, NIST CSF, PCI DSS, and HIPAA.
  • Partner with Legal counsel to ensure corporate compliance with global data privacy regulations, including GDPR and CCPA/CPRA.
  • Design and execute regular enterprise risk assessment programs, identify vulnerabilities, prioritize risks by business impact, and collaborate with department heads on remediation plans.
  • Draft, update, and enforce company-wide information security policies and procedures that adapt to engineering workflows such as CI/CD pipelines and infrastructure-as-code.
  • Oversee the Security Engineering team's partnership with IT Infrastructure to monitor infrastructure security, access controls (IAM), and data encryption protocols.
  • Serve as a key leader on the Incident Response Team, orchestrating investigations, mitigation efforts, and required regulatory disclosures in the event of a breach.
  • Oversee the security vetting process for vendors, software tools, and supply chain partners.
  • Manage external and internal security audits, coordinate evidence collection, manage auditor relationships, and reduce duplicate controls across overlapping frameworks.
  • Represent the company's security posture to enterprise clients, review security questionnaires, participate in prospective client calls, and help build trust to accelerate the sales cycle.
  • Translate complex technical data into concise business metrics for executive leadership and the Board of Directors, and report on the overall risk landscape.
  • Recruit, mentor, and manage a team of security analysts and compliance professionals.
  • Develop and deliver security awareness training programs across business units.

Desired Qualifications

  • One or more relevant industry certifications are highly preferred, such as CISSP, CISM, CISA, CRISC, or CIPP.

About the Company

Twist Bioscience

Produces synthetic DNA for research.

Twist Bioscience designs and manufactures synthetic DNA for biotech, pharma, and research. It uses a proprietary platform to rapidly synthesize custom DNA sequences and checks feasibility with an algorithm before production, giving customers instant feedback. It differentiates itself by handling complex sequences at competitive prices with fast delivery and offering a broad range of products, including genes, oligo pools, variant libraries, SARS-CoV-2 tools, DNA data storage, and NGS services. Its goal is to be a leading, reliable supplier of synthetic DNA and genomics tools to accelerate biotech and pharmaceutical research and development.

Company size
1,001-5,000
Company stage
IPO
Headquarters
South San Francisco, CA
Founded
2013

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