Senior/Principal Scientist - Radiation Science and Theranostic

The Senior Scientist, Radiation Science & Theranostic serves as the primary subject matter expert for molecular imaging workflows across the company's clinical trial portfolio. Acting as a key resource for clinical sites, the Senior Scientist ensures that SPECT/PET image acquisition, data transfer, and radiopharmaceutical handling comply with GCP guidelines and radiation safety standards, directly influencing data-driven decisions throughout the drug development lifecycle.

Typical Accountabilities

• Responsible for providing radiation science expertise and input during the clinical development of RCs, supporting radiopharmaceutical drug development from a radio scientist perspective
• Lead the authoring, cross-functional development, and clinical compliance of radiation related trial documents, including Image Review Charters (IRC), Imaging Operations Manuals (IOM), Data Transmittal Forms (DTF), and Dosimetry Manuals.
• Partner closely with Clinical Operations to manage and oversee the technical, operational, and imaging-related aspects of clinical trials. Ensure all activities adhere strictly to study protocols, timelines, and GCP/ICH regulatory guidelines.
• Direct the internal processing of quantitative image data and lead internal dosimetry modeling and estimation efforts to support ongoing research, multi-disciplinary pipelines, and broader company initiatives.
• Address complex radiation safety inquiries, provide expert counsel regarding diagnostic and therapeutic radiopharmaceutical protocols, and establish clear radiation safety precaution standards for clinical teams.
• Apply a deep working knowledge of modern radiological IT and electronic infrastructure—including DICOM standards, PACS architectures, IHE profiles, quantitative image processing software, and advanced visualization tools.

Qualifications and Skills

• Ph.D. in Medical Physics, or medical imaging technology.
• A minimum of 5 years of relevant industrial experience
• Exceptional verbal and written English fluency and communication skills
• Work experience in radiation department as a medical physicist after Ph.D. graduation
• Direct experience working within clinical trial operations
• Demonstrated experience in clinical imaging site setup, scanner calibration/qualification, and imaging protocol harmonization
• High level of competence in standard business computer applications and hands-on experience navigating advanced medical imaging workstations (e.g., MIM, Hermes, OsiriX, or proprietary vendor workstations)

Date Posted

02-11月-2026

Closing Date

24-1月-2027

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.