Research Scientist 2 - Biology of Adversity Project

The mission of the Broad Institute is to transform medicine by dramatically accelerating the understanding and treatment of disease. The Broad creates a vibrant research environment with close links to top academic institutions, including Harvard, MIT, and the Harvard hospitals. We are committed to building and sustaining a culture that pursues and rewards intellectual curiosity and innovative thinking.

The Biology of Adversity Project (BAP) is a new endeavor at the Broad Institute dedicated to investigating how life adversity leaves “molecular scars” on our genomes that can lead to adverse health effects, with the ultimate goal of finding biological pathways and processes that can be leveraged to improve clinical care.

Role

We are looking for a highly talented and motivated Research Scientist II to join the BAP team to lead our genomics data production and technology onboarding efforts. The candidate will lead the generation of single-cell multi-omics and spatial transcriptomics datasets, from initial tissue processing optimization to final library preparation. They will also lead the onboarding and evaluation of new genomic technologies to determine their feasibility and fit with the BAP's goals. The candidate will join a vibrant, highly collaborative multidisciplinary team of molecular and computational biologists and technology developers.

Key Responsibilities:

• Work with human and animal tissue samples to generate single-cell multi-omics and spatial transcriptomics datasets
• Onboard and evaluate new genomic technologies to determine their feasibility and fit with the BAP's goals
• Design and execute research plans to ensure that critical project requirements, timelines, and deliverables are met
• Troubleshoot scientific problems with minimal guidance
• Track and report progress in an organized fashion, and communicate scientific results to team members
• Supervise and mentor Research Associate(s) and junior team members
• Contribute to various research projects in a collaborative manner

Education and Experience:

• Ph.D. in Molecular Biology or related field with 2+ years of experience
• Extensive molecular biology experience
• Extensive experience with single-cell genomic technologies
• Experience with tissue processing and optimization for single-cell assays
• Excellent technical optimization and problem-solving skills
• Supervising skills
• Strong interpersonal, communication, and collaboration skills to work in a team-oriented environment

The successful candidate will be a results-focused, team-oriented, creative bench scientist able to excel in a fast-paced environment. The candidate must be self-motivated, detail-oriented, and exhibit strong problem-solving skills. In addition, the successful candidate should be a clear and effective communicator, demonstrating strong interpersonal skills to enable collaboration with project teams, peers, and management in identifying and achieving research goals.