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BridgeBio

Develops therapies for genetic diseases

Research Associate 2

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeSan Carlos, CA, USA

About the Job

Requirements

  • A bachelor's or master's degree in Biochemistry, Genetics, Molecular Biology, or Pharmacology.
  • Four to five years of experience in pharmaceutical diagnostics in an R&D or GLP environment.
  • Experience with enzyme assays.
  • Knowledge of GLP practices.
  • Skills in immunoassay and biochemical assay methods.
  • Basic knowledge of immunoassays and fluorescence biochemistry.
  • Ability to work with tissues for in vitro assays.
  • Strong self-motivation and attention to detail.
  • Good time-management skills.
  • Good interpersonal skills, flexibility, and ability to work independently and within a team environment.

Responsibilities

  • Execute, analyze, and report results for biological assays for a preclinical program.
  • Plan and execute experiments to measure the inhibitory activity of small-molecule drug candidates against target proteolytic enzymes.
  • Perform laboratory operations related to enzyme activity and inhibition.
  • Adhere to company standards and current industry standards and practices.
  • Follow safety regulations for handling and disposing of human plasma, serum, and reagents.
  • Maintain laboratory notebooks and forms in accordance with company policies and practices.
  • Perform routine laboratory maintenance and upkeep.

Desired Qualifications

  • Laboratory experience with Western blotting and SDS-PAGE.
  • Hands-on experience with protease assays in plate format using colorimetric or fluorometric detection.

About the Company

BridgeBio

Develops therapies for genetic diseases

BridgeBio Pharma develops medicines for genetic diseases using a decentralized subsidiary model, where each subsidiary focuses on a specific disease while sharing central resources. It advances multiple drug programs at once by leveraging genome sequencing, molecular biology, and patient data to translate research into therapies that target underlying genetic causes. The company differentiates itself through its independent subsidiary structure with centralized support, combined with data-driven decision making and a culture of transparent, evidence-based testing. Its goal is to bring effective, disease-modifying therapies to patients faster by advancing a diverse pipeline from discovery to commercialization through partnerships and eventual approval.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Palo Alto, CA
Founded
2014

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