AbbVie

Global biopharmaceutical company developing medicines

Lead Biotechnologist - Upstream

Bioprocess & BiomanufacturingConfirmed live in the last 24 hours

Full-timeSingaporeNo salary listedIn-person

About the Job

Requirements

A bachelor's degree in sciences such as biological sciences, biomedical sciences, chemistry, life sciences, or pharmaceutical sciences; pharmacy; or engineering such as biomedical, chemical, or pharmaceutical engineering, or equivalent qualification.
At least 5 years of relevant experience in the biologics or pharmaceutical industry, including at least 3 years of area- or upstream-specific experience with inoculation, cell culture, and recovery.
Experience leading a shift team.
Ability to independently handle complex technical assignments and resolve problems in a manufacturing environment.
Knowledge of complex technical issues and manufacturing experience in a biopharmaceutical, pharmaceutical, or similar environment.
Ability to multitask and work in a fast-paced environment while taking ownership of assigned tasks and acting with integrity.
Interpersonal and communication skills.
Experience working shifts.

Responsibilities

Perform cGMP manufacturing operations in a biologics production facility, including working with engineers on setup and calibration, and performing rework and quality testing related to production parts, components, and final materials.
Complete batch documentation accurately and thoroughly while adhering to quality and safety standards and working productively and cost-effectively.
Support and lead operations and troubleshooting during shift work to meet the production schedule and plan.
Serve as Deputy for the Manufacturing Supervisor during the supervisor's absence.
Own upstream operations, including inoculation, cell culture, and recovery.
Plan and execute manufacturing operations using validated programs such as LIMS, SAP, DeltaV, POMSnet, and automated control systems.
Complete manufacturing tasks efficiently, resolve issues, recommend and implement procedures, and independently determine methods and procedures for new assignments.
Drive projects and innovations to streamline processes and operational steps, resolve anomalous processing events, and initiate Demand Work Orders.
Maintain a safe work environment in accordance with regulatory and EHS policies, reinforce safe practices, and lead safety risk assessments or participate in process hazard analyses as an operations representative.
Ensure records are complete and accurate, resolve batch-document errors promptly, communicate events and issues to stakeholders, and prevent human-error-related events.
Maintain plant upkeep during the shift and ensure audit readiness; participate in regulatory audit and inspection preparation; and initiate quality records for non-conformance.
Assist the supervisor with resource planning for production demands, assign tasks to shift biotechnologists, provide inputs about unplanned downtime, and represent the shift in cross-functional meetings.
Promote a positive team environment and exemplify the company's Ways We Work behaviors.
Coach and train other biotechnologists and assist in developing training materials.

Job Description

Purpose:

Performs functions associated with cGMP manufacturing operations within the biologics production facility, including working with engineers in set-up and calibration tasks, as well as performing rework and quality testing related to the production of parts, components, and final materials.
Completes batch documentation accurately and thoroughly, while adhering to the required quality and safety standards, and in a productive, cost-effective manner.
Supports and leads operations & troubleshooting efforts during course of shift work to ensure adherence to schedule and production plan.
Stands in as Deputy for Manufacturing Supervisor in his/her absence.

Major Responsibilities:

Operations and Technical

Demonstrates ownership of upstream-specific operation area, including Inoculation, Cell Culture and Recovery
Plans and executes manufacturing operations using validated programs (such as LIMS, SAP, DeltaV, POMSnet, automated control systems, etc.)
Completes manufacturing tasks efficiently
Demonstrates high degree of initiative to resolve issues
Makes recommendations for and implements new procedures
Acts independently to determine methods and procedures on new assignments
Drives projects and innovations to streamline processes and operation steps
Drives the resolution of anomalous processing events timely
Initiates Demand Work Order

Safety

Ensured safe work environment in accordance with regulatory and global/local EHS policies
Reinforces importance of safety during critical operations and ensure that Positive Interventions and recommendations are regularly highlighted and acted upon.
Leads safety risks assessments or participates in process hazard analysis as an operations representative (PHA)

Quality

Responsible for the completeness and accuracy of all records
Ensures that all batch related document errors are resolved in a timely manner to avoid batch review and release delays
Communicates all events/issues effectively with relevant stakeholders
Drive performance to ensure execution is carried out flawlessly to ensure Human Error related events are prevented
Responsible for overall plant upkeep during the shift and ensuring plant is always in audit ready mode
Is involved in preparation for regulatory audits and inspections
Initiates Quality Records (Non-conformance)

Schedule

Assists supervisor in planning to ensure adequate resources are available to support manufacturing demands per production schedule.
Assigns tasks within the shift team to biotechnologists
Provides inputs to supervisor and manufacturing planner in events of unplanned downtimes
Represents the shift in cross-functional meetings

People and Culture

Sets a positive team environment and exemplifies the AbbVie Ways We Work behaviors
Coaches and trains other biotechnologists (100% trainer competency)
Assists in developing training materials

Qualifications

Bachelors in Sciences (i.e. Biologicals, Biomedical, Chemistry, Life Sciences, Pharmaceutical), Pharmacy, or Engineering (i.e. Biomedical, Chemical, Pharmaceutical), or equivalent
Min 5+ years of relevant work experience in Biologics / Pharmaceutical industry required. Experience should include 3+ years of area / upstream specific experience, including Inoculation, Cell Culture and Recovery
Experience leading a shift team required
Highly skilled specialist and strong problem solver who independently tackles complex assignments with initiative, contributing to the development of innovative concepts and techniques
Demonstrated ability to multi-task and work in a fast-paced environment, takes full ownership of tasks assigned and acts with personal integrity
Knowledge of complex technical issues and manufacturing experience in a biopharmaceutical / pharmaceutical or similar environment
Good interpersonal and communication skills required
Excellent team player, with experience in shift work required

Additional Information

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

About the Company

AbbVie

Global biopharmaceutical company developing medicines

AbbVie is a global biopharmaceutical company that develops and sells medicines to treat serious health conditions. Its portfolio spans immunology, oncology, virology, neuroscience, and aesthetics, with products designed to modulate the immune system, target disease pathways, or support medical aesthetics. AbbVie compounds its products through a heavy emphasis on research and development, investing billions to build a steady pipeline of new therapies. Its medicines are brought to market by selling to healthcare providers, hospitals, and clinics, and in some cases directly to patients via prescriptions. The company differentiates itself through a wide, globally distributed product line, substantial R&D investment, and a commitment to sustainability and patient care, including science-based targets. AbbVie’s goal is to improve patient outcomes by delivering effective treatments for unmet medical needs while pursuing long-term, responsible growth across healthcare markets.

Company size: 10,001+
Company stage: IPO
Headquarters: North Chicago, IL
Founded: 1888

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