Head of Bioengineering

What you´ll do

• Architect integrated biological systems: Define and lead the development of the company’s core technology platform, integrating fluidic, mechanical, sensing, and computational subsystems into cohesive, reliable ex utero support systems.
• Design long-term perfusion and support platforms: Lead engineering design of perfusion architectures, oxygenation systems, mechanical assemblies, and environmental control systems required for stable long-duration biological support.
• Implement systems engineering rigor: Apply closed-loop design principles, redundancy strategies, and failure-mode analysis to ensure robustness, safety, and continuous operation of complex biological platforms.
• Develop sensing and control infrastructure: Oversee integration of biosensors, optical monitoring, embedded systems, and real-time data acquisition pipelines enabling adaptive environmental control and automated experimentation.
• Lead engineering execution: Build, mentor, and guide multidisciplinary engineering teams across mechanical, electrical, software, and computational domains while fostering technical excellence and collaborative problem solving.
• Translate biology into engineering: Partner closely with scientific teams to convert physiological and developmental requirements into engineering specifications and data-driven design decisions.
• Drive technical strategy and delivery: Establish technical roadmaps, manage engineering milestones, and communicate progress and strategy to executive leadership.
• Enable scalable manufacturing: Guide system design toward manufacturability, reliability, and regulatory readiness, supporting future clinical translation.

Core requirements

• PhD or advanced degree in engineering, bioengineering, mechanical engineering, systems engineering, or a related field (or equivalent industry experience)
• 7+ years of post-graduate research or industry experience developing complex integrated engineering or medical device systems
• Strong expertise in systems engineering and closed-loop system design
• Deep knowledge of fluid mechanics and perfusion system engineering, including flow control, shear stress considerations, and long-term sterile circulation
• Experience designing and integrating medical or bioengineering hardware platforms
• Proficiency with sensor integration, embedded systems, and computer-controlled instrumentation
• Experience leading multidisciplinary technical teams and managing complex engineering projects from concept through implementation
• Ability to operate both strategically and hands-on within a fast-paced startup environment

You´ll stand out with

• Systems engineering principles and architecture
• Closed-loop systems and control design
• Failure-mode analysis and redundancy planning
• Fluid mechanics and pump/flow control strategies
• Oxygenator and gas-exchange technologies
• Medical device and mechanical system design
• Biosensors, optical monitoring, and signal filtering
• Real-time data acquisition and control systems
• Precision and sterile manufacturing environments
• Automation and AI-driven experimental systems
• Control theory and reinforcement learning concepts
• Biomaterials, hydrogel systems, and ECM mechanics
• Surface coatings and fouling prevention strategies
• Biocompatibility and protein adsorption dynamics
• Regulatory translation, including FDA medical device pathways
• ISO 13485 and ISO 14971 quality and risk standards

Why e184?

• Unrivaled impact: Your work directly enables technology that transforms human fertility and reproductive medicine.
• Full-spectrum growth: Gain exposure to the entire lifecycle of discovery. From screening to mechanistic validation.
• Best of both worlds: Experience the creative chaos of an early-stage startup with the stability of a well-capitalized company.
• Elite collaboration: Work alongside a world-class team who are as driven as you are.

What we offer

• Competitive salary + equity participation is considered
• State-of-the-art facility in Portland metro area
• Comprehensive Medical, Dental, Vision, and 401(k) with company match
• 31 PTO Days