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Roche

Global pharmaceuticals and diagnostics company

AI Solution Architect

Applied Machine LearningConfirmed live in the last 24 hours
Full-timeShanghai, ChinaNo salary listedIn-person

About the Job

Requirements

  • At least 10 years of experience as a Solution Architect, including at least 2 years of hands-on experience in AI Architecture or AI Platform design.
  • Fluency in both English and Mandarin for architectural discussions with global and local technical teams.
  • Deep mastery of the Kubernetes ecosystem and full-lifecycle cluster management.
  • Extensive experience designing and building MLOps and LLMOps platforms, including familiarity with Kubeflow, MLflow, or Databricks.
  • Deep knowledge of core machine learning components, including Feature Stores, Model Asset Management, Supervised Fine-Tuning, and Model Serving.
  • Familiarity with large-model fine-tuning and inference acceleration frameworks such as DeepSpeed, vLLM, SGLang, and TorchTune.
  • High proficiency in retrieval-augmented generation architecture design.
  • Hands-on experience developing agentic applications with frameworks such as LangChain and LangGraph.
  • Familiarity with vector databases and graph databases.
  • Experience in high-availability system design, disaster recovery, role-based access control, and enterprise components such as single sign-on, LDAP, and bastion hosts.
  • Ability to ensure architectural designs comply with security standards and FinOps governance requirements.
  • In-depth understanding of cloud-native architectures, such as AWS and Alibaba Cloud.
  • High proficiency with the CNCF open-source technology stack, particularly Prometheus, Grafana, OpenTelemetry, and ELK.
  • Hands-on experience with Terraform, Ansible, Packer, and CloudFormation for automated deployment and system security hardening.
  • Mastery of at least one backend development language, such as Python or Go.
  • Experience building end-to-end pipelines with tools such as GitLab CI/CD and JFrog.
  • Familiarity with GPU and high-performance CPU hardware and NAS/SAN storage technologies.
  • Ability to conduct performance benchmarking and hardware selection for high-compute clusters.
  • Understanding of data center network architectures, including out-of-band networks and high-performance RDMA passthrough environments.
  • Mastery of Linux operating systems, including RHEL or CentOS, and proficiency configuring NVIDIA driver and supercomputing driver toolchains.
  • High proficiency in Scrum and Agile development processes and tools.
  • Demonstrated experience leading large-scale AI platforms or projects and mentoring cross-functional teams.

Responsibilities

  • Lead deployment, administration, and lifecycle management of Kubernetes clusters, including scaling, upgrades and rollbacks, certificate rotation, RBAC administration, and cluster teardown; develop automation for cluster operations and drive federated cluster management.
  • Architect, build, and manage MLOps platforms using open-source or commercial frameworks; integrate machine learning lifecycle components and implement metrics for CMCT and drift detection.
  • Design and develop platforms for the large language model lifecycle, integrating data assets, model cards, supervised fine-tuning, and OpenAI-compatible inference, and operationalizing fine-tuning and inference frameworks.
  • Design and implement enterprise AI gateways and integration platforms; establish FinOps, guardrail, and MAAS PrivateLink governance and integrate with GCP Vertex AI, AWS Bedrock, Azure OpenAI, and Ali DashScope.
  • Develop scalable AI and agentic applications using frameworks such as LangChain and LangGraph.
  • Integrate applications across Kubernetes, Slurm, MLOps, LLMOps, AI gateways, and data ecosystems including S3, relational databases, vector databases, and graph databases.
  • Apply Domain-Driven Design to decompose APIs, defining service boundaries, contracts, and data models for complex business requirements.
  • Organize, lead, and mentor engineering teams delivering APIs, web user interfaces, software development kits, command-line interfaces, and applications.
  • Establish coding standards, unit and integration testing protocols, and code review processes.
  • Design and optimize backend systems using REST, gRPC, and GraphQL APIs; SQL and NoSQL databases; Kafka and RabbitMQ messaging; and caching mechanisms.
  • Evaluate and implement architectural patterns such as event-driven architecture, CQRS, Domain-Driven Design, and serverless architecture through trade-off analysis.
  • Oversee the end-to-end AI software development lifecycle and ensure high-quality product delivery.
  • Harden platforms and promote reusable components using CNCF projects such as Prometheus, Grafana, OpenTelemetry, Ray, ELK, and Kubeflow.
  • Design and integrate observability for metrics, logs, and tracing, plus alerting to monitor application performance, usage, and FinOps costs.
  • Ensure architectures meet enterprise standards for high availability, disaster recovery and rollback, security compliance, and component reusability.
  • Integrate platforms with enterprise systems including single sign-on, LDAP, Git repositories, artifact repositories, cloud landing zones, Cloudflare, and AI gateways.
  • Evaluate, benchmark, and select GPU and high-performance CPU bare-metal servers and storage solutions; coordinate data-center power distribution and air or liquid cooling requirements.
  • Architect network topologies and subnets; manage out-of-band, business, and RDMA passthrough networks; and deploy centralized automated monitoring for network equipment.
  • Administer Linux distributions and automate security hardening for large server clusters; manage supercomputing drivers and toolchains including Ansible, Packer, NVIDIA, RDMA, storage drivers, and containerization.
  • Manage private-cloud environments, IAM, data-center direct connections, cloud service security, and data encryption; automate infrastructure using Terraform, CloudFormation, and command-line tools.
  • Configure and maintain enterprise bastion hosts and super-user access controls.
  • Execute large-scale projects using standard Project Management Methodologies and align delivery with pharmaceutical compliance standards.
  • Champion Agile and Scrum, decompose work using WBS, manage Jira backlogs, and coordinate cross-team delivery through GitLab/GitHub CI/CD pipelines and JFrog Artifactory.
  • Design and implement product operational processes for user training and certification, workspace/model/data-asset lifecycle management, and system disclaimers to support safety and compliance.
  • Author architectural documents, large language model specifications, and installation validation protocols.
  • Create, update, and govern technical documentation in GitLab Markdown, Confluence, and GitLab Pages, including process design documents.
  • Lead collaboration across global and local cross-functional teams and provide architectural guidance and mentorship.

Desired Qualifications

  • Experience in the pharmaceutical, life sciences, or top-tier technology industries, including exposure to large-scale compute platforms.
  • Experience with GxP-relevant architecture design.

About the Company

Roche

Global pharmaceuticals and diagnostics company

Roche is a global leader in pharmaceuticals and diagnostics. It develops medicines and diagnostic tools that help detect, monitor, and treat diseases, using research and biotechnology to drive new therapies and tests. Roche combines drug development with in-house diagnostic products to support personalized medicine, where treatments are tailored to individual patients based on test results. Its approach differs from many peers by integrating drug discovery with diagnostic capabilities and by expanding its research through strategic acquisitions (like Genentech) to strengthen its biotechnology and R&D capabilities. The company’s goal is to improve patient outcomes and healthcare worldwide by delivering reliable medicines, accurate diagnostic tests, and data-driven care.

Company size
1-10
Company stage
IPO
Headquarters
Basel, Switzerland
Founded
1896

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