Senior Director - Medical Capabilities

The Position

Let's do something amazing together! We are seeking a Senior Director, Medical Capabilities, to lead the team responsible for scientific medical resources, Medical Information, and medical review across Arrowhead's commercialized and pipeline portfolio, primarily focused on the cardiometabolic therapeutic area. This leader will set priorities, build reliable processes, and develop colleagues while remaining a hands-on contributor to high-priority deliverables. The role ensures that Medical Affairs materials and responses are accurate, balanced, current, useful to their intended audiences, and delivered on time. The Senior Director partners with Medical Affairs colleagues including Field Medical, Medical Strategy, Evidence Generation and Dissemination, Clinical Development, Regulatory, Safety, Legal, and Commercial, as appropriate, and reports to the Group Vice President of Medical Affairs.

This role is based in Pasadena with an expectation to be in office 5 days a week.

Responsibilities

Capability and Team Leadership

• Lead, coach, and develop a team spanning medical resources, Medical Information, and medical review with global purview; define roles, standards, capacity, and development plans.
• Own an integrated, prioritized workplan with clear owners, due dates, review milestones, and weekly status reporting; identify risks early and resolve or escalate barriers.
• Develop and maintain scalable processes, training, quality checks, and systems for intake, authoring, review, and retirement of content.
• Balance strategic direction with personal execution: directly create, critically edit, review, and deliver priority work when scientific complexity, timing, or capacity requires it.

Medical Resources and Scientific Content

• Lead the development and lifecycle management of cardiometabolic disease state and product resources, slide decks, field tools, FAQs, training materials, and congress resources for internal and external scientific exchange.
• Translate clinical, real-world, and published evidence into clear, accurate, appropriately referenced scientific narratives; tailor content to approved audience and use.
• Partner with Medical Affairs colleagues including Medical Strategy, Field Medical, Evidence Generation and Dissemination, and other scientific colleagues to identify content gaps, prioritize updates, and roll out resources with practical training and version control.
• Personally draft or substantially revise complex and time-sensitive resources, including data updates and launch or pipeline materials.

Medical Information

• Lead the Medical Information function and its operating model, including intake, triage, response development, fulfillment, documentation, metrics, vendor oversight, and periodic review of standard responses.
• Ensure responses to unsolicited medical inquiries are evidence based, balanced, accurate, timely, and tailored to the question within applicable policies and procedures.
• Personally handle complex or escalated scientific inquiries and oversee appropriate handoffs to Safety, Quality, or other functions for adverse events, product complaints, and other reportable information.
• Use inquiry trends and feedback to identify evidence gaps, improve standard response documents, and inform Medical Affairs planning and scalability.

Medical Review and Governance

• Provide timely scientific and medical review within the applicable cross-functional review process; assess data interpretation, claim support, references, fair balance, and consistency with current evidence and approved materials.
• Personally review high-priority or complex materials and give specific, actionable feedback that enables accurate and timely resolution.
• Maintain clear review standards, service timelines, documentation, and escalation pathways; partner with Regulatory, Legal, Compliance, and Commercial reviewers while respecting each function’s decision rights.
• Oversee content accuracy and currency through scheduled review, change control, and prompt updates when new data or guidance affect existing materials.

Requirements

• Advanced scientific or healthcare degree (PharmD, PhD, MD, DO, or equivalent) or equivalent combination of education and relevant industry experience.
• 10+ years of relevant biopharmaceutical experience, including substantial work in Medical Affairs, Medical Communications, Medical Information, or medical review.
• Demonstrated ability to lead and develop colleagues, independently write and review scientific content, and manage multiple complex deliverables to deadlines.
• Excellent scientific writing, editing, judgment, and communication skills; able to translate complex evidence into useful materials for different audiences.
• Proven ability to set priorities, meet deadlines, maintain quality under pressure, and communicate progress and risks without prompting.
• Collaborative leader who gives clear direction, holds the team accountable, accepts feedback, and works effectively across functions and regions.
• Strong command of clinical data interpretation, scientific literature, references, and requirements for accurate, balanced medical communications; experience with review and content-management systems preferred.
• Experience in launch readiness, rare disease, cardiometabolic medicine, or RNA-targeted therapeutics is a plus.
• Knowledgeable and comfortable in global and dynamic environment

California pay range 280000 - 300000 USD