IT Director - Development Business Partner

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. 

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll make an impact:

Kymera is seeking an IT Director, Development Business Partner to serve as the senior IT leader embedded within the Development organization. This is a high-impact, strategic role for someone who has navigated the full arc of clinical-stage growth: from early-phase trials through Phase 3, NDA submission, and commercialization. The ideal candidate brings deep expertise in development technology, hands-on experience with Veeva Vault, a strong command of validated systems and regulatory requirements, and the vision to reimagine what those systems and processes can look like in the age of AI.

Reporting to the Senior Director of IT Applications, this person will own the technology strategy and execution across the Development portfolio, build trusted partnerships with Clinical Operations, Clinical/Medical Development, Quality, Biometrics, Data Management, Regulatory, and more, and serve as a thought partner to the IT leadership team as Kymera scales.

Strategic Leadership

• Serve as the primary IT business partner across the Development organization, building trusted relationships with Clinical Operations, Clinical/Medical Development, Quality, Biometrics, Data Management, Regulatory, Program Management, Technical Operations, Medical Affairs, and Pharmacovigilance/Safety.
• In partnership with the Development organization, define and drive the technology roadmap, balancing near-term delivery with long-term strategic positioning for Phase 3 scale and NDA readiness.
• Bring a continuous improvement mindset and a willingness to challenge conventional approaches, identifying opportunities to reimagine and streamline Development processes and systems.
• Partner closely with the AI lead to identify, prioritize, and execute AI-enabled opportunities within the Development portfolio.

Technology Portfolio Ownership

• Lead ongoing and upcoming technology implementations including Veeva Vault QMS, eTMF, and CTMS, partnering with business leads, vendors, and implementation partners to deliver validated solutions on time and with high quality.
• Own the technology strategy and vendor relationships for Kymera's existing Regulatory, Quality, and Biometrics systems, ensuring they are fit-for-purpose, compliant, and scalable.
• Partner with the data analytics lead to ensure data integrations and analytic tools support the evolving needs of the business.
• Scope and evaluate new technology initiatives, as the Development's needs grow. Build and maintain a 2-3 year application roadmap.

Execution and Delivery

• Lead business requirements gathering, process mapping, and solution design across the Development portfolio in an environment without a dedicated PMO.
• Translate complex business requirements into validated, fit-for-purpose technology solutions that meet GxP, 21 CFR Part 11, and other applicable regulatory standards.
• Drive change management, end-user training, and adoption activities to ensure technology investments deliver their intended value.
• Ensure existing systems and integrations are running smoothly.

Skills and experience you’ll bring:

• 12+ years of IT experience supporting the Development organization, in a biotech or pharmaceutical setting.
• Demonstrated experience taking a company through Phase 3 clinical trials, NDA submission, and commercialization. You have done this before and can bring that roadmap knowledge to bear.
• Hands-on experience with Veeva Vault (QMS, eTMF, and CTMS) and a strong command of clinical trial processes, data standards, and GxP requirements.
• Familiarity with statistical computing environments for clinical submissions (SAS-based or equivalent) and the validated systems governance that surrounds them.
• Experience with Regulatory Information Management systems and the requirements of a submission-ready technology landscape.
• A genuine interest in AI and its practical application - not just awareness, but a drive to identify and execute on high-value opportunities.
• Strong strategic instincts paired with a willingness to roll up your sleeves in a lean, fast-moving environment.
• Excellent stakeholder management and communication skills; this role requires building trust across a range of scientific and operational partners.
• Comfort managing vendor and implementation partner relationships and holding them accountable to quality, budget, and timeline commitments.
• Ability to work 3-5 days on-site.
• Advanced degree in a life science or technical area a plus.

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

Compensation

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $195,000 – $275,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
• Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.