Research Associate
Stylus Medicine
Research Associate
Stylus Medicine
In vivo genome editing for CAR-T
About Stylus Medicine:
Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures. Stylus combines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company’s approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.
About the Role:
Stylus Medicine is seeking a highly motivated and collaborative Research Associateto join the Molecular and Cellular Immunology team. In this role, the Research Associate will assist in generating nucleic acid materials and performing in vitro cell experiments, supporting the advancement of genetic medicines that leverage engineered recombinases delivered through non-viral methods. Working closely with cross-functional teams, this is a unique opportunity to work on the front lines of innovation and contribute to the advancement of transformational therapies.
Key Responsibilities & Accountabilities:
Qualifications & Skills:
Pay Range: $85,000-$95,000
In vivo genome editing for CAR-T
Stylus Medicine develops in vivo genetic medicines by combining engineered, therapeutic-grade recombinases with non-viral lipid nanoparticle (LNP) delivery. This platform enables sequence-specific genome integration to insert large genetic payloads directly inside a patient’s body, bypassing the complex steps of ex vivo cell modification. The initial focus is in oncology, delivering a recombinase and a CAR-encoding DNA payload to a patient’s T cells via LNP infusion, effectively turning the patient’s body into an in vivo CAR-T cell factory. The modular system can adapt CAR constructs to target different cancer antigens and holds potential for autoimmune and other genetic diseases beyond oncology. The company positions itself as an off-the-shelf, scalable genetic therapy approach that streamlines treatment workflows and broadens patient access by avoiding traditional ex vivo manufacturing.
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