Simplify Logo

Full-Time

Staff Software Engineer

Data Infrastructure

Confirmed live in the last 24 hours

Helix

Helix

201-500 employees

Integrates genomics into healthcare solutions

Biotechnology
Healthcare

Compensation Overview

$166k - $226.8kAnnually

+ Bonus + Equity

Senior, Expert

Remote in USA

Category
Backend Engineering
Software Engineering
Required Skills
Python
Airflow
Management
Apache Spark
Java
AWS
Scala
Terraform
Requirements
  • Reside in the US, Canada, Mexico, Chile or Colombia
  • Bachelor's/Master's degree in Computer Science, Bioinformatics, Engineering, Mathematics, or a related field with 7+ years of experience; or PhD with 2+ years of experience
  • Proven experience in data engineering
  • Proficiency in Python, Go, Java, Scala, or similar
  • Proficiency with distributed systems built on cloud infrastructure — AWS or similar
  • Experience with infrastructure-as-code tooling/frameworks (e.g., Terraform, Cloudformation, AWS CDK)
  • Experience with authentication protocols such as OAuth, OIDC, SAML, and JWT
  • Proficiency in managing Identity and Access Management (IAM) configurations
  • Expertise with distributed compute frameworks such as Spark, Dask, EMR, Databricks, or similar
  • Expertise with ETL pipeline automation and workflow management tools such as Airflow, AWS Glue, AWS Step Functions, and CI/CD
  • Familiarity with database design, data manipulation, and data quality techniques
  • Adaptable in a fast-paced startup environment where priorities may change quickly and frequently
  • Demonstrated willingness to learn new domains (e.g. genomics, healthcare) and associated technologies
Responsibilities
  • Maintain and evolve infrastructure that allows scientists to process and analyze Helix-produced clinicogenomics datasets.
  • Drive data infrastructure and data management strategy for clinical and genomic data, contributing to platform components and pipelines that increase the value and usability of these key assets.
  • Collaborate and work well cross functionally with product managers, bioinformaticians, scientists, other engineers, and business leaders.
  • Establish and maintain strong engineering best practices.
  • Own systems and services from development to production.
  • Mentor other team members to reinforce a culture of learning and teaching.

Helix focuses on integrating genomics into healthcare to enhance patient care and drive growth for health organizations. They provide solutions that make genomic data accessible and actionable, allowing clients like health systems and life science companies to offer personalized healthcare at scale. Their services improve patient outcomes and reduce costs, creating value for their clients. Helix operates a large clinical Next-Generation Sequencing (NGS) lab, which enables efficient genetic analysis and supports medical research, diagnosis, treatment, and prevention. By collaborating with healthcare organizations, Helix helps public health entities utilize genomic technologies to advance research and respond to health challenges effectively. Their goal is to transform healthcare through the power of genomics.

Company Stage

Series C

Total Funding

$406M

Headquarters

San Mateo, California

Founded

2015

Growth & Insights
Headcount

6 month growth

0%

1 year growth

4%

2 year growth

5%
Simplify Jobs

Simplify's Take

What believers are saying

  • Helix's partnerships with top health systems and public health organizations position it as a leader in population genomics.
  • The launch of clinico-genomic datasets can significantly accelerate precision medicine drug discovery, offering substantial growth opportunities.
  • The appointment of experienced executives like Hylton Kalvaria enhances Helix's leadership and strategic direction.

What critics are saying

  • The highly specialized focus on genomics may limit Helix's market to niche segments, potentially constraining growth.
  • Dependence on partnerships with health systems and public health entities could pose risks if these collaborations falter.

What makes Helix unique

  • Helix's focus on integrating genomics into healthcare sets it apart from competitors who may not emphasize this niche.
  • Their extensive clinical Next-Generation Sequencing (NGS) lab provides a high-throughput DNA sequencing capability that many competitors lack.
  • The company's 'Sequence Once, Query Often' model offers a unique advantage by allowing ongoing genomic insights without the need for additional samples.