Full-Time

Staff Software Engineer

Data Infrastructure

Posted on 7/30/2024

Helix

Helix

501-1,000 employees

Integrates genomics into healthcare solutions

Biotechnology
Healthcare

Compensation Overview

$166k - $226.8kAnnually

+ 15% Annual Bonus + Equity

Senior, Expert

Remote in USA

Category
Backend Engineering
Software Engineering
Required Skills
Python
Airflow
Apache Spark
Java
CloudFormation
AWS
Go
Scala
Terraform
Databricks
Requirements
  • Reside in the US, Canada, Mexico, Chile or Colombia
  • Bachelor's/Master's degree in Computer Science, Bioinformatics, Engineering, Mathematics, or a related field with 7+ years of experience; or PhD with 2+ years of experience
  • Proven experience in data engineering
  • Proficiency in Python, Go, Java, Scala, or similar
  • Proficiency with distributed systems built on cloud infrastructure — AWS or similar
  • Experience with infrastructure-as-code tooling/frameworks (e.g., Terraform, Cloudformation, AWS CDK)
  • Experience with authentication protocols such as OAuth, OIDC, SAML, and JWT
  • Proficiency in managing Identity and Access Management (IAM) configurations
  • Expertise with distributed compute frameworks such as Spark, Dask, EMR, Databricks, or similar
  • Expertise with ETL pipeline automation and workflow management tools such as Airflow, AWS Glue, AWS Step Functions, and CI/CD
  • Familiarity with database design, data manipulation, and data quality techniques
  • Adaptable in a fast-paced startup environment where priorities may change quickly and frequently
  • Demonstrated willingness to learn new domains (e.g. genomics, healthcare) and associated technologies
Responsibilities
  • Maintain and evolve infrastructure that allows scientists to process and analyze Helix-produced clinicogenomics datasets.
  • Drive data infrastructure and data management strategy for clinical and genomic data, contributing to platform components and pipelines that increase the value and usability of these key assets.
  • Collaborate and work well cross functionally with product managers, bioinformaticians, scientists, other engineers, and business leaders.
  • Establish and maintain strong engineering best practices.
  • Own systems and services from development to production.
  • Mentor other team members to reinforce a culture of learning and teaching.

Helix focuses on integrating genomics into healthcare to enhance patient care and drive growth for health organizations. They provide solutions that make genomic data accessible and actionable, allowing clients like health systems and life science companies to offer personalized healthcare at scale. Their services improve patient outcomes and reduce costs, creating strategic value for their clients. Helix operates a large clinical Next-Generation Sequencing (NGS) lab, which enables efficient genetic analysis and supports medical research, diagnosis, treatment, and prevention. By collaborating with healthcare organizations, Helix equips public health entities with advanced genomic technologies, helping them improve disease monitoring and outbreak response. The company's goal is to transform healthcare through genomics, ensuring that innovative therapies reach the market more quickly.

Company Stage

Series C

Total Funding

$399.8M

Headquarters

San Mateo, California

Founded

2015

Growth & Insights
Headcount

6 month growth

0%

1 year growth

0%

2 year growth

0%
Simplify Jobs

Simplify's Take

What believers are saying

  • Helix's AI model predicts semaglutide weight loss response, enhancing personalized obesity treatment.
  • Clinico-genomic datasets accelerate precision medicine drug discovery across multiple disease areas.
  • Partnerships with health systems expand Helix's reach in population genomics and precision medicine.

What critics are saying

  • Ethical concerns arise from AI use in predicting weight loss responses.
  • Data security and patient consent issues may challenge new clinico-genomic datasets.
  • Recruitment challenges and skepticism may affect the Cone Health genomics initiative.

What makes Helix unique

  • Helix operates one of the largest CLIA/CAP next-generation sequencing labs globally.
  • Their proprietary Exome+™ assay supports comprehensive population genomics initiatives.
  • Helix's Sequence Once, Query Often™ model offers ongoing genomic insights without new samples.

Help us improve and share your feedback! Did you find this helpful?

Benefits

Health Insurance

Parental Leave

401(k) Company Match

401(k) Retirement Plan

Unlimited Paid Time Off

Remote Work Options

Home Office Stipend

INACTIVE