Full-Time

Architect – Information Security/Data Privacy

Posted on 3/26/2026

St. Jude Children's Research Hospital

St. Jude Children's Research Hospital

5,001-10,000 employees

Pediatric cancer treatment and research nonprofit

No salary listed

Memphis, TN, USA

In Person

Category
IT & Security (1)
Required Skills
MLOps
Microsoft Azure
Machine Learning
AWS
DevOps
Requirements
  • Bachelor’s degree in computer science, information assurance, MIS or related field, or equivalent. Certification Requirements: an expert level security certification (e.g., CISSP, CISM, OSCP, CASP, etc.)
  • 10+ years in cybersecurity including risk, compliance, and security engineering.
  • Strong experience architecting enterprise security and privacy solutions across datacenters and public, private, and hybrid cloud environments (AWS or Azure preferred).
  • Proven background (5+ years preferred) in enterprise technology design, implementation, and delivery.
  • Deep expertise in cloud computing—SaaS, PaaS, IaaS—and modern cloud security architectures.
  • Mastery of cybersecurity controls including SIEM, IDS/IPS, IAM, PKI, EDR, threat intelligence platforms, and security automation/orchestration.
  • Solid understanding of risk and compliance frameworks such as NIST, ISO 27001, PCI DSS, and privacy regulations.
  • Experience designing secure AI/ML systems and mapping controls to risk and regulatory frameworks.
  • Ability to translate cybersecurity and privacy risks for technical and non-technical executives.
  • Experience architecting SIEM, threat intelligence platforms, SOAR, IDS/IPS, FIM, DLP, and enterprise monitoring tools.
  • Demonstrated ability to lead, mentor, influence, and communicate clearly across diverse engineering and business teams.
Responsibilities
  • Stay ahead of emerging security threats; assess enterprise systems and data to ensure robust defense.
  • Evaluate cutting-edge and disruptive cybersecurity technologies and influence leadership on adoption strategies.
  • Design, validate, and guide deployment of secure solutions that balance data protection, risk, and business value.
  • Lead security and privacy architecture across public, private, and hybrid cloud environments (AWS/Azure).
  • Architect secure business-to-business integrations, third-party solutions, vendor ecosystems, and outsourced services.
  • Own the full-lifecycle security architecture for AI/ML systems, including: Secure data ingestion, Controlled model development, training & deployment, MLOps/DevSecOps integrations, Model integrity, privacy risk assessments & secure inference.
  • Build automated controls that reduce model poisoning, data exfiltration, and AI misuse.
  • Ensure compliance with evolving data privacy and AI regulations.
  • Partner with legal, risk, and compliance teams to ensure adherence to regulatory and ethical requirements (privacy laws, AI regulations, internal risk frameworks).
  • Develop and maintain security and data privacy standards, policies, procedures, and processes.
  • Influence and participate in incident response planning and post-incident reviews, establishing measurable benchmarks.
  • Apply a DevSecOps mindset focused on automation, operational efficiency, and scalable architecture.
  • Drive security automation that increases team capacity for advanced work and reduces manual workload.
  • Stress-test security controls and platforms to validate performance while protecting business operations.
  • Coach, mentor, and lead engineering, development, and business partners on security-by-design and privacy-by-design principles.
Desired Qualifications
  • Experience with AWS or Azure cloud security tools and architectures.
  • AI/ML security experience, including model governance and secure MLOps.
  • Proficiency in scripting languages such as Python, PowerShell, JavaScript, PHP, or Ruby.
  • DevOps/DevSecOps background with compliance-driven engineering practices.
  • Knowledge of: ISO 27001, NIST, PCI DSS, HIPAA, HITECH, GDPR, CIS, SOC 2, and state privacy laws.
  • Strong strategic and tactical decision-making capabilities.
  • Highly trustworthy and leads with integrity and professionalism.
St. Jude Children's Research Hospital

St. Jude Children's Research Hospital

View

St. Jude runs a nonprofit pediatric treatment and research center focused on childhood cancers, especially leukemia. It provides treatment and covers medical costs, travel, housing, and meals for patients and families, with no bills to families. Care comes from clinical treatment at the hospital while researchers develop therapies and run trials; results are shared openly with doctors worldwide. Its goal is to cure childhood cancer and relieve families’ financial burden by sharing knowledge globally.

Company Size

5,001-10,000

Company Stage

Grant

Total Funding

$54.8M

Headquarters

Memphis, Tennessee

Founded

1962

Your Connections

People at St. Jude Children's Research Hospital who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • Reserves reached $7.6 billion, enabling expanded family benefits like increased travel support.
  • Charles W. M. Roberts leads pediatric cancer cure advancements as EVP and Director.
  • Active regional fundraising offices in Denver sustain ALSAC contributions.

What critics are saying

  • ProPublica exposes $7.6 billion hoarding while families drain savings on uncovered costs.
  • Aggressive estate lawsuits against donors' families erode public trust immediately.
  • NCI cuts federal grants by 20-30% within 6-12 months slash research budget.

What makes St. Jude Children's Research Hospital unique

  • St. Jude is sole NCI-Designated Comprehensive Cancer Center for pediatric patients since 1977.
  • Nonprofit model covers all treatment, travel, housing, food without billing families.
  • Freely shares research globally, boosting childhood cancer survival from 20% to over 80%.

Help us improve and share your feedback! Did you find this helpful?

Benefits

Health Insurance

401(k) Retirement Plan

401(k) Company Match

Unlimited Paid Time Off

Maternity / Paternity Leave

Fertility Treatment Support

Adoption Assistance

Education Assistance

Enterprise Learning and Development

Company News

Tubefilter
Dec 1st, 2020
YouTube’s Latest Original Is A Charitable ‘Secret Santa’ Exchange With AsapSCIENCE, Molly Burke, More

YouTube’s brand new holiday original is one giant 'Secret Santa' gift exchange -- with myriad charity tie-ins and the involvement of 12 of the platform’s most beloved channels. Premiering today, with all 12 episodes live now, The Great Gift Exchange will see creators partake in a giving chain -- with each installment benefiting a charity of their choosing, all while paying it forward to the next creator on the chain. The series is hosted by gift wrap artist Alton DuLaney, who will educate viewers on the art of gift wrapping while wrapping each charitable donation in a creative manner that’s bespoke to each creator’s personal brand. Participants in The Great Gift Exchange -- who count a combined 78 million subscribers -- include: AsapSCIENCE (Rainbow Railroad), Molly Burke (Mira Foundation), Shalom Blac (St. Jude), Rosanna Pansino (Feeding America), Physics Girl (The Malala Fund), Alex Wassabi (Make-A-Wish Foundation), Kristopher London (The Bail Project), Ambers Closet (Lunch on Me), Jennelle Eliana (Covenant House), Smosh Games (Okra Project), MatPat (No Kid Hungry), and Kurt Hugo Schneider (Bat Conservation). YouTube’s brand new holiday original is one giant 'Secret Santa' gift exchange -- with myriad charity tie-ins and the involvement of 12 of the platform’s most beloved channels.

PYMNTS
Nov 11th, 2020
Blackhawk Network Buys National Gift Card

Global branded payments provider Blackhawk Network has acquired National Gift Card, one of the biggest North American prepaid tech and card companies, according to a press release emailed to PYMNTS.

Tubefilter
Oct 14th, 2020
Digital Creator-Focused Charity Platform Tiltify Raises $6.5 Million

Creator-centric fundraising platform Tiltify, which has been harnessed by the likes of Jacksepticeye, Markiplier, DrLupo, Jordan Fisher, and Emilia Clarke to raise money for a whole host of charities, has just announced a venture funding round of its own totaling $6.5 million.

INACTIVE