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Compass Pathways

Develops psilocybin-based therapies for TRD

Director, Health Economics & Outcomes Research

Biology & BiotechConfirmed live in the last 24 hours
Full-timeRemote in USA

About the Job

Requirements

  • An advanced degree (M.D., D.O., Pharm.D., Ph.D., or MPH/MS) in a relevant scientific or health-related discipline, such as health economics, pharmacoeconomics, epidemiology, health services research, public health, or clinical sciences, is required.
  • A minimum of 8–12+ years of pharmaceutical or biotechnology experience is required, including 5+ years in field HEOR, Value/Outcomes Liaison, or Market Access roles presenting to and engaging with payer customers in collaboration with Market Access.
  • Demonstrated knowledge of health economics methodology, including cost-effectiveness analysis, budget impact modeling, quality-adjusted life years (QALYs), systematic reviews, and meta-analyses.
  • Strong understanding of the U.S. payer landscape, formulary management, and reimbursement processes.
  • Proven ability to translate complex scientific and economic data into clear narratives for payer and access audiences.
  • A valid driver's license and ability to travel 50–70% of the time by car and air.
  • Applicants must have employment rights in the country to which they are applying; employment visas cannot be sponsored.

Responsibilities

  • Identify, cultivate, and maintain peer-to-peer relationships with key payer thought leaders, medical and pharmacy directors, formulary decision makers, Chief Medical Officers, Chief Pharmacy Officers, and other healthcare decision makers within the assigned geography.
  • Deliver fair-balanced, scientifically rigorous presentations on clinical trial data, real-world evidence, pharmacoeconomic models, and patient-reported outcomes.
  • Respond to unsolicited medical information requests from payer and access stakeholders with accurate, compliant, and timely scientific content.
  • Attend and represent the organization at managed care, payer, and scientific conferences to maintain awareness of current landscape issues and emerging data.
  • Partner with internal HEOR, real-world evidence, and Medical Affairs teams to identify evidence gaps and support the design, execution, and dissemination of field-based observational studies, retrospective analyses, and pharmacoeconomic research.
  • Facilitate investigator-initiated and collaborator-initiated research proposals and coordinate with appropriate internal stakeholders for review and approval.
  • Support development and communication of health economic models, cost-effectiveness analyses, and budget impact tools for payer audiences.
  • Contribute to publications, posters, and abstracts for scientific meetings and peer-reviewed journals.
  • Gather and synthesize field intelligence on evolving payer policies, formulary decisions, coverage criteria, value-based contracting trends, and competitive landscape dynamics.
  • Communicate insights to internal stakeholders, including Medical Affairs, Market Access, HEOR, and Commercial teams, to inform strategy and evidence planning.
  • Monitor and interpret changes in managed care regulations, government payer policy (CMS, Medicare, Medicaid, VA/DoD), and health technology assessment methodologies.
  • Serve as a scientific resource to Market Access Account Directors, Commercial teams, and other field-based colleagues; provide training on disease state, clinical data, and health economics topics.
  • Collaborate with Medical Science Liaisons, Global Medical Affairs, and HEOR headquarters teams to align field activities with overarching medical strategy.
  • Collaborate with the Market Access team to educate and inform payers about clinical and health economic aspects of Compass Pathways’ investigational and on-market products.
  • Participate in advisory board activities, scientific symposia, and payer-focused medical education programs.
  • Complete required training, compliance reporting, and administrative responsibilities in accordance with corporate policy and applicable law.
  • Ensure all field activities comply with legal, regulatory, and industry (PhRMA/AMCP) guidelines, with particular attention to controlled-substance and REMS-related communication standards.

About the Company

Compass Pathways

Develops psilocybin-based therapies for TRD

COMPASS Pathways develops psilocybin-based therapies for mental health, focusing on treating treatment-resistant depression (TRD). Its lead drug candidate, COMP360, is a high-purity psilocybin formulation given alongside psychological support from trained therapists. The treatment is delivered through a global Phase 3 program, aiming to establish a regulatory-approved therapy. Compared with other players, COMPASS emphasizes a standardized therapeutic model that pairs a pharmaceutical compound with guided psychotherapy and has the largest psilocybin Phase 3 program to date, supported by Breakthrough Therapy designation from the FDA. The company originated from a nonprofit idea, transformed into a for-profit entity to fund extensive trials, and is pursuing regulatory approval and eventual commercialization through licensing and partnerships. Its goal is to bring approved, evidence-based psilocybin treatments to patients with TRD and scale access through a commercial pathway.

Company size
201-500
Company stage
IPO
Headquarters
London, United Kingdom
Founded
2016

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