synergy

CRDMO offering full product lifecycle services

Organic Synthesis Chemist

Translational Research & Bench BiologyUpdated on Nov 7

Full-timeDallas, TX, USANo salary listedIn-person

About the Job

Requirements

A Master’s degree or PhD in Organic Chemistry or a related field is required.
At least 7 years of hands-on experience in the organic synthesis of enantiomeric compounds is required.
Experience with multi-step organic synthesis and route optimization is required.
Deep knowledge of stereochemistry, enantiomeric synthesis, reaction mechanisms, synthetic methodologies, and analytical techniques is required.
Hands-on experience documenting work in GMP-compliant laboratory environments is required.
Experience working closely with analytical scientists, including interpreting characterization data, coordinating method support, and partnering on project timelines, is required.
Hands-on experience with HPLC, GC-MS, and LC-MS is required.

Responsibilities

Design and perform multi-step organic syntheses to produce enantiomeric chemical entities.
Develop and optimize synthetic routes to improve yield, purity, and scalability of enantiomeric chemicals.
Document experimental procedures, data, and results accurately in lab notebooks and reports, following good documentation practices.
Collaborate with analytical scientists to support project goals and timelines.
Ensure compliance with safety, GMP, and regulatory requirements in all laboratory activities.
Troubleshoot synthetic scheme challenges, characterization data, and reaction conditions, and propose solutions.

Desired Qualifications

Experience with chiral chromatography and NMR is a plus.

Organic Synthesis Chemist

Synergy Bioscience Inc · Dallas, United States · Full-time · Posted 2026-08-12

Workplace: on_site

Department: Product Development

Description

Synergy Bioscience is a contract research, development, manufacturing, testing, and consulting organization serving pharmaceutical, biopharmaceutical, and medical device clients. The company supports product development through analytical, testing, and regulatory expertise, helping clients move complex programs forward with scientific rigor, quality, and precision.

In this role, you will contribute to chemistry programs focused on the development of enantiomeric chemical entities. This is an opportunity to apply deep organic synthesis expertise in a collaborative laboratory environment, working closely with cross-functional scientific partners to advance project goals while maintaining high standards for quality, documentation, and compliance.

Responsibilities

Design and perform multi-step organic syntheses to produce enantiomeric chemical entities.
Develop and optimize synthetic routes to improve yield, purity, and scalability of enantiomeric chemicals.
Document experimental procedures, data, and results accurately in lab notebooks and reports, following good documentation practices.
Collaborate with analytical scientists to support project goals and timeline.
Ensure compliance with safety, GMP, and regulatory requirements in all laboratory activities.
Troubleshoot synthetic scheme challenges, characterization data, and reaction conditions, and propose innovative solutions.

Requirements

Master’s degree or PhD in Organic Chemistry or a related field.
7+ years of hands-on experience in the organic synthesis of enantiomeric compounds.
Experience with multi-step organic synthesis and route optimization.
Deep knowledge of stereochemistry, enantiomeric synthesis, reaction mechanisms, synthetic methodologies, and analytical techniques.
Hands-on experience documenting work in GMP-compliant laboratory environments.
Experience working closely with analytical scientists, including interpreting characterization data, coordinating method support, and partnering on project timelines.
Hands-on experience with HPLC, GC-MS, and LC-MS; experience with chiral chromatography and NMR is a plus.

Benefits

Health Care Plan (Medical, Dental & Vision)
Paid Time Off (Vacation, Sick & Public Holidays)
Training & Development

Apply

Apply at Synergy Bioscience Inc

About the Company

synergy

CRDMO offering full product lifecycle services

Synergy Bioscience provides CRDMO/CDMO services for pharma, biotech, and medical devices. It supports the product lifecycle with fee-for-service work, including method development and validation, analytical testing, biocompatibility studies, residual solvent analysis, and clinical research to move products from concept to market. The firm differentiates itself by serving small-to-mid-sized companies with cost-effective, high-quality, end-to-end laboratory and regulatory support across USP/EP/ISO standards. Its goal is to be a dependable technical partner that helps clients navigate regulatory requirements and bring products to market.

Company size: 1-10
Company stage: Not listed
Total funding: Not listed
Headquarters: Dallas, TX
Founded: 2016

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