Purification Development Co-op @ Flagship Pioneering

Spring 2024 Co-op Job Description Template

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first redosable and targetable DNA medicines. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.

Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ:MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health (AXLA), Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

The Purification Development Co-op will primarily be focused on developing manufacturing processes for recombinant protein and viral vector products. The responsibilities of the Co-op will include conducting experiments using small scale, and high-throughput chromatography systems; and filtration units to develop, characterize, and optimize new processes. The Co-op will additionally gain experience with common analytical workflows such as SDS-PAGE, Western Blots, plate-based biochemical assays and analytical HPLC.

The position will require interaction with multiple co-workers and functioning in a team environment, and the candidate should be able to organize and communicate ideas and results in a clear and concise manner.

This co-op session will run January 10 – June 26, 2023.

Basic Qualifications:

Ability to work full-time onsite in Cambridge, MA
Knowledge of AKTA chromatography systems
Familiarity with software for data analysis (Excel, JMP, Graphpad)

Preferred Qualifications:

Preference given to grad students, and those with previous co-op experience

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.