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Alnylam Pharmaceuticals

Develops RNAi-based therapies for genetic diseases

Director Head of Incentive Compensation & Execution Excellence

Sales OperationsConfirmed live in the last 24 hours
Full-time$204k - $276k

About the Job

Requirements

  • A bachelor's degree or better is required.
  • At least 10 years of experience in incentive compensation, field enablement, and/or commercial effectiveness is required.
  • Proven experience designing and operationalizing incentive compensation plans tied to behavior and execution is required.
  • A strong understanding of sales motions, frontline execution, and manager-led coaching is required.
  • Experience defining and using key performance indicators to drive adoption and performance change is required.
  • The ability to translate data into actionable insights is required.
  • Experience leading, coaching, and developing dynamic teams of high-performing individuals is required.
  • The ability to present to executive audiences is required.
  • A track record of delivering solutions with attention to detail, accuracy, and derived value is required.
  • A sense of urgency balanced with a focus on quality and process is required.
  • Project management skills and the ability to lead multiple projects and priorities are required.
  • The ability to travel for key external and internal meetings as needed is required; the role involves approximately 10% overnight travel.

Responsibilities

  • Design and manage incentive compensation plans that drive desired field behaviors, execution excellence, and strategic priorities.
  • Translate business goals into clearly defined measures of success, including quantifiable targets and performance metrics.
  • Partner with Finance, HR, Legal, Compliance, and Sales to ensure incentive compensation plans are compliant, scalable, and financially sound.
  • Lead annual and quarterly compensation planning cycles, including scenario modeling and performance forecasting.
  • Own compensation plan communication, field readiness, and ongoing interpretation to ensure clarity and adoption.
  • Ensure enablement efforts tied to incentive compensation are measurable, behavior-based, and linked to key performance indicators.
  • Provide strategic oversight of incentive and bonus programs to ensure they are executable, motivating, compliant, and fiscally responsible.
  • Lead accurate and timely execution of incentive compensation plans, including payout calculations, documentation, and governance.
  • Define short- and long-term solutions for incentive compensation administration, enabling scalable capabilities, tools, and technology to support a growing and increasingly complex field organization; partner with Commercial Enablement, IT, and other internal teams to deliver these solutions.
  • Provide strategic leadership for the Incentive Compensation and President’s Club programs in partnership with field leadership, HR, and Finance.
  • Make data-driven recommendations on compensation design and goal-setting methodologies, informed by modeling, testing, and validation.
  • Conduct regular incentive compensation health checks, including goal attainment, payout distributions, and advantaged or disadvantaged segments, to ensure plans perform in line with design objectives.
  • Develop materials to communicate plan designs to field teams, including design documents, incentive compensation statements, ranking reports, and payout estimators.
  • Define and operationalize leading and lagging key performance indicators that measure execution quality, adoption, and outcomes.
  • Work with the Advanced Analytics team to build dashboards and reporting that provide actionable insights at the representative, manager, and leadership levels.
  • Monitor performance trends to identify risks, opportunities, and coaching needs.
  • Translate insights into targeted actions for leaders and frontline managers.
  • Enable frontline managers with coaching frameworks, performance insights, and incentive literacy.
  • Partner with Sales Leadership and Training to embed coaching into operating rhythms, such as quarterly business reviews.
  • Support managers in diagnosing performance issues and reinforcing behaviors tied to incentives and enablement.
  • Promote a culture of continuous improvement, accountability, and data-driven coaching.

About the Company

Alnylam Pharmaceuticals

Develops RNAi-based therapies for genetic diseases

Alnylam Pharmaceuticals develops RNA interference (RNAi) therapeutics to silence disease-causing genes, aiming to treat rare genetic disorders. Its products work by using RNA molecules that block gene expression, reducing the impact of specific genetic diseases. The company differentiates itself by concentrating on RNAi-based drugs for rare diseases and by building a pipeline through large clinical programs and strategic partnerships, such as commercialization deals in the Gulf States and collaborations with investors. Revenue comes from approved drug sales, licensing agreements, strategic collaborations, and related services like genetic testing and counseling. The company’s goal is to advance and commercialize RNAi therapies to improve outcomes for patients with genetic disorders, expanding its portfolio through partnerships and investments.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Cambridge, MA
Founded
2002

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