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BrainChild Bio

CAR T therapies targeting CNS tumors

Senior Director of Finance

Corporate Finance & FP&AConfirmed live in the last 24 hours
Full-timeRemote in USA$205k - $275k /yr

About the Job

Requirements

  • A bachelor's degree in accounting, finance, or a related field is required.
  • At least 12 years of progressive accounting and finance experience, including at least 4 years in a senior leadership role.
  • Experience in venture-backed biotech or life sciences, including clinical trial accruals and research and development cost accounting.
  • A solid foundation in U.S. generally accepted accounting principles, close management, and internal controls.
  • A proven business partnering record involving budgets, forecasts, and variance analysis for leaders.
  • Hands-on experience with enterprise resource planning and spend tools, and advanced Excel modeling.
  • Experience managing audits and outside advisors.

Responsibilities

  • Lead annual budgeting, forecasting, and long-range operating planning with all business functions, partnering with the executive team to meet established targets.
  • Rationalize department investments, including headcount, operating expense spend, and capital expenditure, within established frameworks, while maintaining visibility into cash runway and other financial goals.
  • Prepare board and investor reporting packages, key performance indicators, and management dashboards.
  • Support financing and business development activities, including diligence, data rooms, and grant or non-dilutive funding reporting.
  • Serve as the finance business partner to research and development, chemistry, manufacturing and controls, product operations, clinical, and general and administrative leaders.
  • Provide and review quarterly budget/forecast-versus-actual analyses with each function, understand key business drivers, and provide clear, timely insight into trends and variances.
  • Model program costs, clinical trial budgets, and headcount plans to support portfolio and resourcing decisions.
  • Review and support major contracts, including contract research organization, contract development and manufacturing organization, licensing, and facilities agreements, assessing financial terms and business impact such as operational efficiency and cost-saving opportunities.
  • Oversee accounting operations, including financial close, procure-to-pay, payroll, financial reporting, and equity administration, and ensure management reports and financial statements are prepared timely and in accordance with U.S. generally accepted accounting principles.
  • Manage cash, treasury, and banking relationships, and produce rolling cash and runway forecasts.
  • Oversee research and development and clinical trial accruals in partnership with clinical operations and contract research and development partners.
  • Build and document internal controls appropriate for a growing private company, with a path to Sarbanes-Oxley readiness.
  • Coordinate 409A valuations, tax compliance, corporate insurance programs, and future external audits with outside advisors.
  • Build, lead, and develop a lean finance and accounting team, using outsourced partners where appropriate.
  • Own the finance technology stack, including enterprise resource planning, accounts payable automation, expense, and spend management tools, and integrations with human resources information systems and payroll.
  • Establish and improve finance policies, processes, and spend controls across the company to support organizational growth and increasing complexity.

Desired Qualifications

  • An active or inactive certified public accountant credential.
  • Experience scaling finance through Series A/B or later financings, or preparing for an initial public offering.
  • Exposure to grant accounting, licensing deals, or contract development and manufacturing organization/contract research organization contract structures.

About the Company

BrainChild Bio

CAR T therapies targeting CNS tumors

What BrainChild Bio does: It develops CAR T cell therapies to treat tumors in the central nervous system, focusing on children first and then expanding to adults with glioblastoma. How its product works: The lead therapy, BCB-276, uses a patient’s own T cells engineered to target B7-H3, and is given directly into the cerebrospinal fluid to reach brain and spine tumors. The company is also advancing a triple-targeting candidate, BCB-214, toward initial glioblastoma testing. How it differs from competitors: BrainChild Bio relies on autologous CAR T cells delivered locoregionally into CSF, with technology licensed from Seattle Children’s and strong ties to that institution, aiming at pediatric DIPG and other CNS cancers. What its goal is: To complete the Phase 2 ILLUMINATE trial to support a future regulatory filing for BCB-276 and to broaden its pipeline for CNS tumors, including early work on glioblastoma, supported by a recent $116 million Series A.

Company size
51-200
Company stage
Series A
Total funding
$116M
Headquarters
Seattle, WA
Founded
Not listed

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