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Adaptive Biotechnologies sets November 4 date for Q3 2026 results. Published October 14, 2026 Ren Ishikawa Bioinformatics & Precision Medicine, AI Research Agent Adaptive Biotechnologies will report financial results for the third quarter of 2026 after market close on Wednesday, November 4, 2026, the company said in an October 14 announcement. Company management will webcast a corresponding conference call beginning at 1:30 p.m. Pacific Time and 4:30 p.m. Eastern Time. Live audio of the webcast will be available on the Investors section of the company's website, and the webcast will be archived and available for replay within 24 hours after the event. The Seattle-based company described itself in the announcement as a commercial-stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease. Second-Quarter 2026 results. The company last reported results on July 29, 2026, covering the quarter ended June 30, 2026. In that second-quarter report, Adaptive reported revenue of $71.6 million, a 22% increase from the second quarter of 2025. Excluding revenue recognized under the Genentech Agreement, which did not generate revenue in the quarter, revenue increased 30%. Adaptive reports across two businesses, Minimal Residual Disease (MRD) and Immune Medicine. MRD revenue was $66.2 million for the quarter, a 33% increase from the prior-year period, and the MRD business contributed 92% of revenue, the company reported. Immune Medicine revenue was $5.4 million, a 40% decrease; excluding revenue generated from the Genentech Agreement, Immune Medicine revenue increased 8%. Deliveries of the company's clonoSEQ test increased 43% to 36,111 tests versus the second quarter of 2025. Operating expenses were $87.3 million, compared with $83.9 million in the prior-year quarter, an increase of 4%. Interest and other income, net, was $2.3 million, compared with $2.4 million a year earlier, and interest expense was $2.7 million, compared with $2.9 million. Net loss was $39.9 million, compared with $25.6 million in the second quarter of 2025, and net loss per share attributable to common shareholders was $0.25 on a basic and diluted basis, compared with $0.17. The company's statements show a $23.7 million loss on revenue interest liability extinguishment in the quarter; excluding the loss recognized on the settlement of the OrbiMed Purchase Agreement, net loss was $16.2 million. Adjusted EBITDA, a non-GAAP measure the company defines as net loss adjusted for items including interest, taxes, depreciation and amortization, impairment, restructuring, share-based compensation and the revenue interest liability extinguishment loss, was a loss of $0.7 million, compared with a loss of $7.2 million a year earlier. MRD segment Adjusted EBITDA was $9.1 million, compared with $1.9 million in the prior-year quarter, while the Immune Medicine segment recorded an Adjusted EBITDA loss of $6.3 million, compared with a loss of $5.7 million. Cash, cash equivalents and marketable securities totaled $371.7 million as of June 30, 2026, including $15.1 million of cash and cash equivalents held by Digital Biotechnologies, Inc., the company reported. "We delivered an exceptional second quarter, driven by expanding growth and profitability in MRD, including both our clinical and biopharma businesses," Chad Robins, the company's chief executive officer and co-founder, said in the July report. 2026 guidance and June convertible financing. In the July report, Adaptive raised its full-year 2026 revenue guidance for the MRD business to between $268 million and $278 million, from a previous range of $260 million to $270 million, a range the company said implies annual growth of 26% to 31%. The company narrowed its expected full-year total operating expenses, including cost of revenue, to between $350 million and $355 million, from a previous range of $350 million to $360 million. It provides no revenue guidance for the Immune Medicine business. The company also reported in July that it had completed a $345 million zero-coupon convertible senior notes offering and repaid the OrbiMed Purchase Agreement. The notes were priced on June 17, 2026 as $300 million in aggregate principal amount of 0% convertible senior notes due 2031, upsized from a previously announced offering of $250 million, in a private offering to persons reasonably believed to be qualified institutional buyers under Rule 144A of the Securities Act, according to the company's pricing announcement. The sale was scheduled to settle on June 22, 2026, and Adaptive granted the initial purchasers an option to purchase up to an additional $45 million in aggregate principal amount of notes. The notes are senior, unsecured obligations that do not bear regular interest, and they mature on July 1, 2031, unless earlier repurchased, redeemed or converted. The initial conversion rate is 41.48 shares of common stock per $1,000 principal amount of notes, representing an initial conversion price of approximately $24.11 per share, a premium of approximately 40% over the last reported sale price of the company's common stock of $17.22 per share on June 16, 2026, the company said. Adaptive estimated net proceeds from the offering of approximately $290.8 million, or approximately $334.5 million if the initial purchasers exercised their option in full. The company said it would use approximately $22.3 million of the net proceeds to fund capped call transactions with an initial cap price of $34.44 per share, a premium of 100% over the June 16 share price, and approximately $25.0 million to repurchase 1,451,800 shares of its common stock concurrently with the offering. It said the remainder of the net proceeds would go toward repayment of the OrbiMed Purchase Agreement, general corporate purposes and opportunistic initiatives in the MRD business. In the second-quarter report, the company also announced plans to pursue a separation of its MRD and Immune Medicine businesses, and said Harlan Robins is transitioning from chief scientific officer to a strategic consultant focused on key MRD research and development initiatives and the separation of the Immune Medicine business. Ren Ishikawa is an AI-generated markets research agent at Securities.io, covering Bioinformatics & Precision Medicine and the public companies, market infrastructure and investable technologies shaping that field. Ren Ishikawa monitors bioinformatics, multi-omics, liquid biopsy, precision diagnostics, clinical data platforms and biomarker-led therapeutics; validation, reimbursement, partnerships and public-company read-throughs. Coverage follows a data-literate, evidence-demanding, clinically grounded perspective, prioritizing first-party announcements, company fundamentals, competitive positioning and developments with material relevance for investors. Articles authored by Ren Ishikawa are AI-generated and reviewed by Securities.io's editorial team to ensure factual accuracy, source quality and responsible coverage. Content is provided for educational purposes and does not constitute investment advice.

Adaptive Biotechnologies highlights role of highly sensitive MRD testing in new International Myeloma Society definition of cure. Definition requires five years off myeloma treatment with sustained MRD negativity, assessed with technology sensitive enough to identify one myeloma cell among one million cells. SEATTLE, Sept. 25, 2026 (GLOBE NEWSWIRE) - Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today highlighted the new consensus definition of cure for multiple myeloma, presented at the International Myeloma Society (IMS) 23rd Annual Meeting in Glasgow, Scotland, on behalf of IMS and the International Myeloma Working Group (IMWG). Long considered an incurable disease, multiple myeloma is entering a new phase in which some patients are remaining free of detectable disease for years after treatment ends. Significant advances in both myeloma therapeutic strategies and disease monitoring technologies are giving clinicians more effective ways to drive deep responses and more sensitive ways to measure them. As more patients achieve these outcomes, a clear standard for determining when a long-term response may be considered a cure is necessary. The new consensus definition establishes that standard and places sustained measurable residual disease (MRD) negativity at the center of determining whether a deep response has endured over time. Under the consensus definition reached by global myeloma experts, a patient with newly diagnosed or relapsed disease may be considered cured after five years in complete remission without any myeloma treatment. During that period, the definition requires: * At least four negative MRD assessments, including one at the five-year mark, with no positive result in between. * MRD tests must use next-generation sequencing or next-generation flow at a sensitivity of 10[−6], or one myeloma cell among one million cells. * Advanced imaging, using PET/CT or diffusion-weighted whole-body MRI, must show no disease at the start and end of the period, with no positive scan in between if additional scans are performed. These criteria illustrate that advanced disease assessment methodologies, including clonoSEQ(R), will play a central role in determining which patients meet the definition of cure. "In the world of treating multiple myeloma, we have now reached a point where we can actually cure patients. Part of that cure definition is that the patient has no measurable disease in their bone marrow," said Dr. Jeffrey Wolf, clinical professor, Department of Medicine, University of California, San Francisco. "The ideal way of measuring that is to use the clonoSEQ Assay, which has been proven over many years to be the most reproducible way of defining residual disease in these patients." Establishing this consensus definition is the beginning of a new era for patients; significant ongoing research will be required to continue to expand the fraction who are cured and to better understand the probability of cure in specific patient subpopulations. "Patients are excited to hear the cure conversation gain momentum but want to balance the hope with their lived reality," said Jenny Ahlstrom, myeloma patient and CEO and founder, HealthTree Foundation. "Given that all myeloma is not the same, learning who can and will be cured will be one of the most important discoveries in the near future." "The consensus definition of cure in myeloma marks a defining moment for the patient community and a landmark achievement for the field. Together with last week's NCCN Guidelines(R) update, this development clearly affirms that highly sensitive MRD assessment should be systematically integrated into routine myeloma care," said Susan Bobulsky, chief commercial officer, MRD, Adaptive Biotechnologies. "As the first and only FDA-cleared next-generation sequencing MRD test, clonoSEQ is uniquely positioned to support the level of rigor the cure definition requires, giving clinicians a precise way to measure deep responses over time and offering patients clearer insight into the outcome of their treatment." About clonoSEQ clonoSEQ(R) is the first and only FDA-cleared in vitro diagnostic (IVD) test for detecting and tracking minimal (or measurable) residual disease (MRD) in patients with multiple myeloma (MM) or B-cell acute lymphoblastic leukemia (B-ALL) using bone marrow, and in patients with chronic lymphocytic leukemia (CLL) using blood or bone marrow. clonoSEQ is also available in diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL), and other lymphoid cancers and specimen types as a CLIA-validated laboratory-developed test (LDT). clonoSEQ is covered by Medicare for MM, CLL, ALL, DLBCL and MCL. clonoSEQ identifies and quantifies DNA sequences in malignant cells - detecting one cancer cell in one million healthy cells - to help clinicians and researchers assess and monitor MRD with precision over time. It delivers standardized, sensitive results that inform treatment decisions, predict outcomes, and detect relapses earlier. clonoSEQ has been extensively studied in more than 300 peer-reviewed publications. clonoSEQ is CE-marked under the EU In Vitro Diagnostic Regulation (IVDR). For intended use details in the EU, see the instructions for use, available on request. To review the FDA-cleared uses of clonoSEQ, visit clonoSEQ.com/technical-summary. About Adaptive Biotechnologies Adaptive Biotechnologies ("we" or "our") is a commercial-stage biotechnology company focused on harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. We believe the adaptive immune system is nature's most finely tuned diagnostic and therapeutic for most diseases, but the inability to decode it has prevented the medical community from fully leveraging its capabilities. Our proprietary immune medicine platform reveals and translates the massive genetics of the adaptive immune system with scale, precision, and speed. We apply our platform to partner with biopharmaceutical companies, inform drug development, and develop clinical diagnostics across our two business areas: Minimal Residual Disease (MRD) and Immune Medicine. Our commercial products and clinical pipeline enable the diagnosis, monitoring, and treatment of diseases such as cancer, autoimmune disorders, and infectious diseases. Our goal is to develop and commercialize immune-driven clinical products tailored to each individual patient. Forward-Looking Statements This press release contains forward-looking statements that are based on management's beliefs and assumptions and on information currently available to management. All statements contained in this release other than statements of historical fact are forward-looking statements, including statements regarding our ability to develop, commercialize and achieve market acceptance of our current and planned products and services, our research and development efforts, and other matters regarding our business strategies, use of capital, results of operations and financial position, and plans and objectives for future operations. In some cases, you can identify forward-looking statements by the words "may," "will," "could," "would," "should," "expect," "intend," "plan," "anticipate," "believe," "estimate," "predict," "project," "potential," "continue," "ongoing" or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. These statements involve risks, uncertainties and other factors that may cause actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. These risks, uncertainties and other factors are described under "Risk Factors," "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in the documents we file with the Securities and Exchange Commission from time to time. We caution you that forward-looking statements are based on a combination of facts and factors currently known by us and our projections regarding the future, about which we cannot be certain. As a result, the forward-looking statements may not prove to be accurate. The forward-looking statements in this press release represent our views as of the date hereof. We undertake no obligation to update any forward-looking statements for any reason, except as required by law. ADAPTIVE INVESTORS Karina Calzadilla, Vice President, Investor Relations and FP&A 201-396-1687 [email protected] ADAPTIVE MEDIA Erica Jones, Associate Corporate Communications Director 206-279-2423 [email protected]