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Xaira Therapeutics

AI-powered protein design for therapeutics

Vice President, Business Development and Alliance Management

Business Development & PartnershipsConfirmed live in the last 24 hours
Full-timeSouth San Francisco, CA, USAIn-person

About the Job

Requirements

  • Significant experience in business development, corporate development, licensing, strategic partnerships, or a related role within biotechnology, pharmaceuticals, TechBio, or a relevant technology organization.
  • Demonstrated experience leading and closing large, complex strategic transactions.
  • Strong experience originating and executing sell-side business development opportunities.
  • Demonstrated experience managing strategic alliances from transaction execution through ongoing governance, delivery, and expansion.
  • Ability to understand complex scientific and technical capabilities, including AI-enabled technologies, and translate them into strategic and commercial value.
  • Strong knowledge of transaction structures, valuation principles, financial terms, intellectual property considerations, and deal governance.
  • Experience working closely with scientific, technical, legal, finance, operations, and executive teams.
  • Established credibility and relationships across the pharmaceutical, biotechnology, or technology partnering ecosystem.
  • Ability to operate effectively in a fast-moving environment where strategy, technology, AI capabilities, and partnership models continue to evolve.

Responsibilities

  • Partner with the Senior Vice President of Business Development and Operations to develop and execute Xaira’s business development strategy.
  • Identify opportunities for major AI platform, technology, research, and multi-program partnerships.
  • Translate Xaira’s scientific and technical capabilities, including its AI-enabled discovery and development capabilities, into clear and compelling partnership opportunities.
  • Develop a prioritized pipeline of potential partners and transactions aligned with Xaira’s long-term strategy.
  • Assess market trends, competitive activity, partner needs, and emerging business models across TechBio, AI, and biopharma, including the evolving landscape for AI-driven drug discovery partnerships.
  • Provide strategic recommendations to senior leadership regarding partnership opportunities, deal structures, and market positioning.
  • Proactively originate significant partnership opportunities with pharmaceutical, biotechnology, technology, and other strategic organizations.
  • Build and maintain senior-level relationships with decision-makers across the biopharma and technology ecosystem.
  • Lead early discussions with potential partners to understand their scientific, technical, and business priorities, including opportunities to apply AI across research and development.
  • Develop partnership concepts that connect external needs with Xaira’s platform, expertise, and strategic priorities.
  • Build opportunities beyond traditional single-asset licensing, including platform collaborations, multi-program partnerships, technology alliances, AI-focused collaborations, and other strategic transactions.
  • Represent Xaira at industry meetings, partnering conferences, and other external forums.
  • Lead major transactions from initial concept and partner engagement through diligence, negotiation, internal approval, and execution.
  • Develop creative deal structures that may include upfront payments, research funding, milestones, royalties, option rights, co-development arrangements, and other economic components.
  • Ensure deal structures appropriately reflect the long-term value of Xaira’s platform, AI capabilities, and intellectual property.
  • Lead cross-functional transaction teams involving scientific, technical, legal, finance, operations, and executive stakeholders.
  • Develop transaction strategies, valuation frameworks, negotiation positions, and executive recommendations, including approaches for valuing differentiated AI technologies and platform capabilities.
  • Prepare materials for executive leadership and Board review.
  • Maintain momentum, accountability, and clear decision-making throughout complex deal processes.
  • Work closely with scientific and technical leaders to define the scope, objectives, deliverables, and resource requirements of potential partnerships, including partnerships involving AI models, technologies, and workflows.
  • Partner with finance to assess deal economics, valuation, resource commitments, and financial scenarios.
  • Partner with legal to negotiate agreements that protect Xaira’s intellectual property and long-term strategic flexibility, including considerations related to AI-generated insights and outputs.
  • Ensure proposed partnership commitments are aligned with internal capabilities and company priorities.
  • Build alignment across stakeholders on transaction strategy, economics, risks, and decision points.
  • Support the transition of executed partnerships into alliance management and ongoing governance.
  • Lead the transition of executed transactions from deal teams into effective alliance management, ensuring continuity between the original strategic intent and partnership execution.
  • Establish and maintain governance structures, decision-making processes, communication plans, and escalation pathways for strategic alliances.
  • Serve as a senior point of contact for external partners and build productive relationships across scientific, technical, operational, and executive stakeholders.
  • Partner with internal teams to track contractual obligations, deliverables, milestones, resource commitments, and financial considerations.
  • Ensure partnerships involving AI-enabled research, technologies, and development programs remain aligned with agreed objectives, responsibilities, data requirements, and measures of success.
  • Identify and resolve risks, misalignment, and execution challenges before they affect partnership outcomes.
  • Identify opportunities to expand successful alliances into additional programs, technologies, disease areas, or AI-driven collaborations.
  • Provide senior leadership with clear updates on alliance performance, risks, decisions, and opportunities for continued value creation.
  • Help define how Xaira presents its platform, capabilities, and partnership model to the external market.
  • Develop clear and differentiated narratives for scientific, technical, executive, and business audiences, including the role of AI in advancing drug discovery and development.
  • Identify new partnership models that reflect the evolving intersection of biotechnology, artificial intelligence, data, and drug discovery.
  • Strengthen Xaira’s position as a strategic partner for complex, AI-enabled research and development collaborations.
  • Build market awareness of Xaira’s capabilities and the potential value of partnering with the company.

Desired Qualifications

  • Experience with platform, technology, AI, research collaboration, multi-program, or discovery-stage partnerships is strongly preferred.
  • An advanced scientific or technical degree, MBA, JD, or equivalent experience is valued but not required.

About the Company

Xaira Therapeutics

AI-powered protein design for therapeutics

Xaira Therapeutics uses artificial intelligence to transform drug discovery and development. It builds a pipeline of protein- and antibody-based therapeutics by combining generative AI models from the IPD lab (notably RFdiffusion and RFantibody) with large, multidimensional biological data. The company designs novel proteins and antibodies from scratch to target difficult, previously undruggable biology, then validates and evolves these molecules through iterative data generation that improves its biological foundation models. Unlike many entrants that offer research services, Xaira aims to own and advance its own therapeutic pipeline across multiple modalities, rather than solely providing platforms. The goal is to deliver effective new medicines faster and with a lower chance of failure by integrating AI-driven design, expansive data, and expert leadership.

Company size
201-500
Company stage
Late Stage VC
Total funding
$1B
Headquarters
South San Francisco, CA
Founded
2023

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