Director – Clinical Operations

Posted on 5/7/2024

Vor Bio

Vor Bio

51-200 employees

Developing cell therapies for blood cancers


Senior, Expert

Cambridge, MA, USA

Required Skills
  • Minimum of BA/BS with a minimum of 8 years of clinical trial and clinical program experience
  • Experience with Cell and Gene Therapy is highly desirable and 4+ years Phase 1-3 experience in Oncology is required
  • Robust experience in early and late phase global drug development
  • Multi-dimensional Clinical Operations background with capability of devising plans for operational challenges
  • Cross-collaboration proficiency with other functions such as Regulatory, CMC, Biostatistics, Data Management, Finance, Program Management, etc.
  • Advanced working knowledge of current FDA, ICH, GCP regulations and guidelines
  • Experience in GCP inspections/audits
  • Outstanding verbal and written communication skills
  • Proven track record of effective leadership and team-building skills in the biotech or pharmaceutical industry
  • Resilient, creative, capable problem-solver
  • Excellent organizational skills and ability to work independently
  • Experience in establishing and maintaining relationships with key opinion leaders
  • Ability and willingness to travel up to 20%
  • Executes the day-to-day operations of clinical trials from the protocol concept through the clinical study report
  • Develops and manages comprehensive trial timelines and metrics
  • Ensure that clinical trials are properly resourced, managed and executed within budget and in accordance with established timelines and quality standards
  • Develop and manage trial budget(s) and maintain within financial goals
  • Drive selection, management and oversight of external vendors
  • Lead the identification and management of third-party Clinical Operations vendors
  • Perform and document trial level Sponsor Oversight of outsourced clinical activities
  • Manage invoice and budget tracking for individual trials
  • Review and provide functional input into relevant clinical documents
  • Prioritize day-to-day issues and Corporate/Clinical goals
  • Provide real-time updates to Senior Management and cross-functional teams
  • Oversee/collaborate on and contribute to inspection readiness activities
  • Coordinate activities related to audit findings and/or identification of significant site noncompliance
  • Develop relationships with Key Opinion Leaders
  • Coach and provide guidance to Clinical Operations team
  • Train and mentor junior staff on Clinical Operations processes
  • Maintain oversight and participate in the creation/review/training/maintenance of departmental and organizational SOPs
  • Strive for continuous improvement and more efficient ways of working within the Clinical team
  • May serve as subject matter expert (SME) in one or more areas

Vor Bio is dedicated to transforming the treatment of blood cancers through a combination of advanced Hematopoietic Stem Cell biology, genome engineering, and CAR-T cell technology. By focusing on making healthy cells resistant to targeted therapies, this company offers a unique workplace for those passionate about cutting-edge healthcare solutions. Its strong commitment to research and development in oncology positions it as a leader in the industry, providing employees with the opportunity to be at the forefront of medical science and contribute to significant advancements in patient care.

Company Stage


Total Funding



Cambridge, Massachusetts



Growth & Insights

6 month growth


1 year growth


2 year growth