Full-Time
Updated on 8/21/2026
Delivers digital twin for metabolic health.
$125k - $145k/yr
No H1B Sponsorship
Remote in USA
Remote
Applicants must be authorized to work for any employer in the U.S.
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Twin Health uses a Whole Body Digital Twin to monitor metabolism and guide personalized treatment for chronic metabolic diseases like diabetes. The platform gathers data from sensors, builds a real-time virtual model of a person’s metabolism, and uses AI to suggest individualized care, with ongoing coaching and updates. It differentiates itself by targeting the root metabolic dysfunction with a continuous, data-driven twin and by forming partnerships with healthcare providers and payers for integrated care. The goal is to reverse and prevent metabolic diseases by restoring healthy metabolism through scalable, subscription-based care.
Company Size
501-1,000
Company Stage
Series E
Total Funding
$286.5M
Headquarters
Mountain View, California
Founded
2018
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Health Insurance
Dental Insurance
Vision Insurance
401(k) Retirement Plan
Unlimited Paid Time Off
Parental Leave
Health Savings Account/Flexible Spending Account
Company Equity
Remote Work Options
Flexible Work Hours
Twin Health has launched a GLP-1 Stewardship Model aimed at reducing long-term dependence on GLP-1 medications for weight loss. The Digital Twin Care Platform uses AI and biometric data to personalise treatment and guide patients safely off medications when clinically appropriate. A randomised clinical trial published in the New England Journal of Medicine Catalyst showed 85% of Twin participants successfully discontinued GLP-1s whilst losing twice as much weight as the control group. Members maintain or continue losing weight after discontinuation. The model offers employers four coverage options with flexible spending controls. A recent analysis estimated employers save $7,532 per employee over two years. Twin's platform monitors continuous glucose, activity and quarterly labs to provide real-time guidance on food, sleep and stress responses.
Twin Health introduces precision GLP-1 Stewardship Model, helping members lose more weight without long-term dependence. PR Newswire Today at 8:38am PDT Digital Twin Care Platform supports sustained weight loss, shortens treatment, and lowers the total cost of care for employers and health plans MOUNTAIN VIEW, Calif., May 21, 2026 /PRNewswire/ - Twin Health, the first Digital Twin Care Platform for cardiometabolic health, today announced the launch of its GLP-1 Stewardship Model to reduce long-term dependence on GLP-1s. The Digital Twin Care Platform enables a precision approach to GLP-1 use for weight loss that shortens treatment duration, sustains weight loss, and lowers the total cost of care for employers and health plans, with flexible tools to manage spending. "GLP-1 medications can be highly effective, but many care models fail to define an evidence-based strategy for treatment duration or medication discontinuation. As a result, patients are often left on therapy indefinitely, contributing to unnecessary long-term cost and pharmacologic dependence," said Dr. Lisa Shah, Chief Medical Officer and Executive Vice President of Twin Health. "Our approach emphasizes stewardship of the entire treatment continuum, from start through maintenance, with a clear clinical framework for when therapy can be safely reduced and, when appropriate, discontinued." Today, there is no clear standard for how long patients should stay on GLP-1s or how to safely come off. As a result, treatment often becomes open-ended, with limited visibility into when or how patients should taper or discontinue. Demand is growing fast, and most employers face the same difficult choice: cover the drugs and absorb open-ended pharmacy costs, or withhold access and frustrate employees who need support. For members, the picture is no better: side effects with limited clinical guidance, and the quiet assumption that staying on the drug is the only way to keep the weight off. A Model Based on Outcomes, Not Prescriptions Twin's GLP-1 Stewardship Model is tied to clinical outcomes, not GLP-1 utilization. Employers choose how to structure access. Twin actively manages each member through treatment and guides them safely off the drug when the data show they are ready. Twin works across four coverage models: * Program-gated access through the pharmacy plan * Open coverage with clinical oversight * Defined contribution approaches that cap employer spend from day one * Employer-facilitated access through direct-to-consumer pathways with no plan changes required Twin fits the way employers actually need to make decisions. In a recent employer cost analysis of the Twin healthy weight and prediabetes programs, employers saved an estimated $7,532 per employee over 2 years, inclusive of less GLP-1 utilization over time. Twin is already trusted by leading employers to treat cardiometabolic disease without long-term dependence on high-cost medications: "At Medline, we focus on long-term metabolic health by addressing root causes like insulin resistance, inflammation, and overall cardiometabolic risk," said Angela Sim, Vice President of Benefits at Medline. "Through our partnership with Twin, many employees have improved related key markers - including A1C and kidney function - and in some cases achieved Type 2 diabetes remission. This approach supports sustainable lifestyle changes, improving outcomes while reducing reliance on medications." Digital Twin Care Platform Proven to Shorten GLP-1 Use and Improve Health Twin Health is proven to help patients safely eliminate high-cost medications and sustain weight loss by addressing the underlying causes of metabolic disease. In a randomized clinical trial published in the New England Journal of Medicine Catalyst, 85% of Twin participants successfully discontinued GLP-1s, and lost 2 times more weight than participants in the control group. In Twin's commercial population, members maintain or continue to lose weight after GLP-1 discontinuation. At the heart of the GLP-1 Stewardship Model is Twin's patented AI Digital Twin, a continuously learning model of each member's biology and behavior. To personalize the guidance for members, the Digital Twin Care Platform uses biometric data, including quarterly labs, a smart scale, a continuous glucose monitor, and a physical activity tracker. Members receive hour-by-hour personalized guidance to change their behavior based on their response to food, sleep, activity, and stress. The AI Digital Twin equips clinicians with real-time insight that no traditional prescriber has access to. A Twin provider determines clinical eligibility before the first prescription, and monitors each member's real-time metabolic data throughout to adjust dosing, build habits that outlast the medication, and initiate structured tapering when clinical signals indicate the member is ready. About Twin Health Twin Health is the first cardiometabolic care model built to reverse disease, prevent progression, and sustain lifelong health. Twin pairs expert clinical care with a proprietary AI Digital Twin that continuously learns how an individual's biology responds to daily life. Expert clinicians use that real-time insight to guide precision decisions every day, across diabetes, healthy weight, and the full cardiometabolic spectrum. Twin has demonstrated improved cardiometabolic outcomes, reduced reliance on high-cost medications, and annualized savings of more than $9,000 per member for employers and health plans. Clinical outcomes are peer-reviewed and published in leading journals, including the New England Journal of Medicine Catalyst and publications of the American Heart Association, American Diabetes Association, and American College of Cardiology. Learn more at usa.twinhealth.com. SOURCE Twin Health This is a paid placement. For further inquiries, please contact PR Newswire directly.
Peloton's newest tech bet: AI Digital twins. Utilizing its digital twin technology, Twin Health will incorporate Peloton's content library to recommend personalized workouts to members based on their unique profiles. A new partnership between Peloton and Twin Health is uniting the breakthrough technology of digital twins and fitness. The healthtech company will now integrate the fitness brand's content to integrate Peloton's library of live and on-demand classes with Twin Health's hyper-personalized AI digital twin care plan, the latest innovation in personalized wellness. Here's how that digital twin works: Twin Health's technology creates a real-time model of your unique metabolism, drawing upon data from smart devices, lab results and meal logs. That model then provides personalized guidance on nutrition, movement, sleep and more, with the support of a clinical team. With the help of Peloton, the AI digital twin will recommend specific workouts or content based on a member's personalized metabolic health goals. That could look like low-impact cardio for a member focused on heart health, yoga for stress management or meditation to boost sleep quality. The partnership arrives soon after a study published in the New England Journal of Medicine Catalyst found Twin Health's AI Digital Twin to be an effective treatment for diabetes and weight loss without medications. Twin members will receive a Peloton App One membership at no additional cost, with the option to add a reduced-cost Peloton Bike+ rental or a Peloton All-Access membership. "At Peloton, we have long held that movement is medicine. Our interest in improving people's health outcomes is about putting that belief into action at scale, which we can accomplish with Twin Health," said senior vice president and general manager of Peloton for Business, Greg Hybl. "Together, we are pairing connected fitness and wellness with clinical care to unlock life-changing health outcomes for more people than ever before."
Twin Health raises $53M in Series E funding round.
Twin Health, a metabolic health startup, raised $53 million in a Series E funding round, reaching a valuation of over $950 million. The round was led by Maj Invest, with participation from Iconiq and Temasek. Twin Health's digital twin technology, which helps manage diabetes and other metabolic disorders, has shown promising results, with 71% of study participants lowering their A1C levels and often stopping medication. The company aims to scale commercially across more employers and health plans.