Neion Bio

Egg-based biopharmaceutical manufacturing platform

Viral Vector Scientist - Gene Therapy

Translational Research & Bench BiologyConfirmed live in the last 24 hours

Full-timeNew York, NY, USAIn-person

About the Job

Requirements

A PhD, or a BA with 7+ years of experience, or an MS with 5+ years of experience, in biological sciences, bioengineering, molecular biology, genetics, a science-related field, or equivalent experience.
Experience cloning large libraries or large viral genomes.
Experience transfecting and transducing difficult target cells or tissues.
Experience producing, purifying, characterizing, validating, and testing viral vectors, including adenovirus, lentivirus, and AAV.
Deep understanding of cellular biology, receptors for viral entry and trafficking, mechanisms involved in viral transduction, and immunology.
Experience with ultracentrifugation and resin- and column-based viral purification methods.
Experience in genome engineering, cloning, DNA amplification, PCR, next-generation sequencing, transfections, and other molecular biology skills.
Strong aseptic techniques and good laboratory practice procedures.
Organizational skills and the ability to manage time and priorities effectively.
Strong written and oral communication skills and creative problem-solving skills.

Responsibilities

Perform cloning of large viral genomes, focusing on capsid modification through rational design or directed evolution.
Perform transfections on primary cells, immortalized cells, and animal tissues.
Design, manufacture, purify, characterize, validate, and test viral vectors at small and large scales.
Design experiments and generate and analyze datasets to adapt vector strategies for avian systems.
Assess workflow efficiency through cellular assays and next-generation sequencing approaches.
Extract DNA, RNA, and protein from animal tissue; design and run PCR, qPCR, RT-PCR, and ELISA assays to quantify viral transgene, transcription, and protein.
Conduct experiments and work on research problems.
Maintain electronic laboratory records.
Work on project milestones.
Attend laboratory meetings and prepare reports and presentations on project progress.

Desired Qualifications

Experience working with avian viruses or AAVs, or adapting viral vector strategies for use in avian systems.
Extensive experience with and knowledge of adenoviral vectors.
Experience with viral capsid engineering through rational design or directed evolution.
Experience with viral capsid library engineering.

Viral Vector Scientist - Gene Therapy

Neion Bio · New York, United States · Full-time · Posted 2026-09-14

Salary: USD 120,000–150,000

Workplace: on_site

Description

Neion Bio is harnessing nature’s best molecular factory, the chicken egg, to make medicine affordable, accessible, and resilient. Using cutting edge genetic engineering and stem cell technology, we create “living bioreactors”, which act as fully autonomous 3D biomolecular printers, operating on existing industrial-scale infrastructure. Our platform can rapidly and scalably produce almost any protein, provide national resilience to drug shortages and de-risk complex supply chains, and ultimately take advantage of novel biological environments to solve unmet medical needs. We are on a mission to reimagine the way in which complex biological molecules are produced to transform human health.

At Neion Bio you will play a pivotal role in an early-stage, fast-growing company, working alongside leading scientists and entrepreneurs. You will have the opportunity to participate in the enormous potential upside while having a huge impact on the world.

We are looking for a talented virologist or molecular biologist on the scientist level experienced with the engineering, production and purification of viral vectors, including lentivirus, adenovirus and AAV; and with a deep understanding of the underlying receptor biology of viral vector transduction of cells, ideally in non-model organisms. This is a hands-on role.

Key Responsibilities:

Perform cloning of large viral genomes, with a focus on capsid modification by either rational design or directed evolution
Perform transfections on primary cells, immortalized cells, and animal tissues
Design, manufacture, purify, characterize, validate and test a range of viral vectors, at small and large scale
Design experiments, generate and analyze datasets allowing to adapt vector strategies to use in avian systems
Assess efficiency of workflows through cellular assays and NGS sequencing approaches
Extract DNA, RNA, protein from animal tissue, design and run PCR, qPCR, RT-PCR, ELISA assays to quantify viral transgene and transcription, protein
Conduct experiments and work on research problems
Maintain excellent electronic laboratory records
Work on project milestones
Attend lab meetings, prepare reports and presentations on the progress of projects

Requirements

PhD (or BA with 7+ years of experience/MS with 5+ years of experience) in biological sciences, bioengineering, molecular biology, genetics, or any science related field, or equivalent experience
Experience with cloning large libraries or large viral genomes
Experience with transfection and transduction of difficult target cells/tissues
Experience producing, purifying, characterizing, validating and testing of a range of viral vectors including adenovirus, lentivirus, AAV
Deep understanding of the cellular biology, receptors for viral entry and trafficking, mechanisms involved in viral transduction, and immunology
Experience with ultracentrifugation and with resin and column based viral purification methods
Experience in genome engineering, cloning, DNA amplification, PCR, NGS, transfections, and other molecular biology skills
Strong aseptic techniques and GLP procedures
Exceptional organizational skills with the ability to effectively manage time and priorities
Strong written and oral communication skills, as well as creative problem-solving skills
Curious, eager, and hardworking

Preferred qualifications:

Experience working with Avian viruses or AAVs or adapting viral vector strategies for use in avian systems
Extensive experience with and knowledge of adenoviral vectors
Experience with viral capsid engineering by rational design or directed evolution
Experience with viral capsid library engineering

Benefits

Compensation: base salary is expected to be $120-150K depending on experience, with additional bonus compensation, equity compensation, and benefits including health insurance, dental insurance, vision insurance, and 401(k).

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About the Company

Neion Bio

Egg-based biopharmaceutical manufacturing platform

Neion Bio develops the Raptor platform, which uses genetic engineering to turn chicken eggs into living bioreactors that produce recombinant biologics such as monoclonal antibodies. By re-engineering eggs and growing avian germ cells, the company can manufacture therapeutic proteins inside eggs, aiming to lower capital costs and reduce the carbon footprint compared to traditional cell-culture methods. The business model centers on partnerships with pharmaceutical companies, offering co-development and supply agreements that provide upfront and milestone payments plus future profit sharing when products reach the market. Neion Bio differentiates itself from competitors by using egg-based bioreactors and precision genome engineering to enable cost-effective, localized production with a potentially simpler supply chain. The company’s goal is to transform biologic manufacturing by delivering affordable, scalable bioproduction for a wide range of biologic medicines and related molecules.

Company size: 11-50
Company stage: Series A
Total funding: $23M
Headquarters: New York City, New York
Founded: 2024

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