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BeOne

Global oncology therapeutics discovery, development, manufacturing

Executive Director - Clinical Business Operations

Clinical Research OperationsConfirmed live in the last 24 hours
Full-timeRemote in USA

About the Job

Requirements

  • A bachelor's degree or above in Life Sciences, Medical Science/Medicine, Finance, Health Economics, or a related field.
  • At least 14 years of experience in clinical operations, study start-up, clinical site budgets, or clinical site contracts within a pharmaceutical sponsor or contract research organization environment.
  • Strong planning and organizational skills and the ability to lead a team effectively in a dynamic environment with competing priorities.
  • Strong executive communication skills and the ability to present data-driven insights to senior leadership.
  • A solution-driven, results-focused approach and willingness to take a hands-on approach to work.
  • Ability to analyze complex financial data and translate insights into actionable guidance.
  • Experience working cross-functionally with Clinical Operations, Finance, Payments, and Legal stakeholders.
  • Advanced proficiency in Excel and data analytics tools.
  • Good knowledge of ICH-GCP and pharmaceutical-related regulations and laws.
  • Ability to travel 10%.

Responsibilities

  • Drive operational excellence, financial stewardship, compliance, scalability, and digital transformation initiatives across the Clinical Business Operations team.
  • Oversee investigator budgets, site contracts, site payments, and the budget data hub team to ensure precise budget forecasting, efficient site contract execution, timely and accurate site payments, and accurate budget data entry in databases.
  • Lead workforce planning, talent acquisition, succession planning, capability development, performance management, and development of a high-performing, agile, continuously improving team.
  • Align regional execution strategies with global governance frameworks, including accountability models, decision-making processes, and issue escalation mechanisms across cross-functional and cross-country stakeholders.
  • Establish and lead recurring governance cadences, including quarterly business reviews, escalation forums, and executive reporting, to manage and communicate risks, trends, and operational performance.
  • Own and monitor operational and financial performance indicators across investigator budgeting, site contracting, payments, and budget data governance, including site contract cycle time and execution timeliness, budget forecast accuracy and forecast-versus-actual variance, and site payment timeliness and reconciliation accuracy.
  • Provide strategic oversight of investigator fee budget planning to support accurate financial forecasting.
  • Direct the development, review, negotiation, and timely execution of site budgets and clinical trial agreements in alignment with fair market value principles, study requirements, company standards, and study start-up timelines.
  • Supervise end-to-end site payment and reconciliation processes to ensure financial obligations are processed accurately and according to contractual terms and payment schedules.
  • Oversee collection, validation, and maintenance of budget-related information in designated databases and systems to support data integrity and accuracy.
  • Ensure budget, contract, payment, and supporting operational documentation remains audit-ready and compliant with applicable regulatory, financial, and internal governance standards.
  • Maintain oversight of Sunshine reporting obligations and global transparency requirements, ensuring processes, controls, and stakeholder alignment are implemented across regions.
  • Provide strategic oversight of outsourced vendors and external business partners, including performance monitoring, service quality oversight, issue escalation, and governance.
  • Partner with Corporate Finance on financial governance, including oversight of accruals, forecast-versus-actual, and reconciliation processes.
  • Oversee operational finances and team resources to keep activities within approved budgets and resource allocations.
  • Provide leadership, guidance, and performance management to team members, fostering accountability, collaboration, and continuous improvement.
  • Support implementation of automation tools and digital solutions to improve productivity.

Desired Qualifications

  • At least 20 years of experience is preferred.
  • Experience with budget systems and contract lifecycle management platforms is preferred.

About the Company

BeOne

Global oncology therapeutics discovery, development, manufacturing

BeOne Medicines discovers, develops, and commercializes oncology therapies worldwide, focusing on hematologic cancers and solid tumors. Its products work by leveraging internal R&D and clinical development to bring therapies to market quickly, with Brukinsa serving as a leading backbone in the US and European markets. It differentiates itself through a large-scale global clinical network and cost-efficient development and manufacturing that support high margins and a focus on large-market cancer indications. Its goal is to expand access to high-impact, affordable cancer treatments across more than 45 countries while growing its pipeline into immunology and solid tumors.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Dongcheng District, China
Founded
2010

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