Edgewise Therapeutics

Develops therapies for rare muscular disorders

Associate Director/Director Cardiovascular Pharmacology

Translational Research & Bench BiologyConfirmed live in the last 24 hours

Full-timeBoulder, CO, USAIn-person

About the Job

Requirements

A Ph.D. or equivalent experience in cardiovascular physiology or a closely related field, with postdoctoral and industry experience.
At least 8 years of academic or research laboratory experience.
Exceptional understanding of scientific literature in the relevant area of science or research.
Demonstrated cardiovascular expertise, including a publication track record.
Technical expertise in in vitro and in vivo cardiovascular techniques across a range of species, with strong molecular and multi-omics expertise.
Ability to work independently and lead independent scientists.
Familiarity with safe and efficient laboratory practices.
General proficiency with scientific computer and software applications.

Responsibilities

Independently design, manage, and execute experiments aligned with scientific goals across ongoing company projects.
Conduct detailed and complex wet laboratory experiments, or manage a team conducting them, using appropriate techniques and controls to substantiate and replicate results.
Coordinate and direct research among scientific disciplines in relation to assigned projects.
Manage a group of independent researchers.
Research and identify new opportunities and project ideas that complement the company’s mission, vision, values, and goals.
Establish appropriate objectives when formulating successful project strategies.
Influence company program direction by designing experiments and collaborations, interpreting, analyzing, and correlating data from multiple sources, overcoming obstacles, and delivering results within project timelines.
Increase team or group performance by critically reviewing work processes and offering insightful input and suggestions.
Produce and review individual and team scientific reports and presentations for internal or external purposes.
Work with consultants and collaborators to understand results and their impact on project goals.
Participate in project team meetings.
Maintain scientific records in the required clear form.
Contribute an advanced-level scientific perspective to patent efforts.
Update job knowledge by attending scientific meetings, participating in educational opportunities, reading professional publications, maintaining professional networks, and participating in professional organizations.
Understand and comply with workplace health and safety policies, safe work practices, and company policies and procedures.
Perform other duties as assigned by a supervisor.

At Edgewise, we are focused on advancing novel, muscle-targeted therapeutics for serious cardiovascular and cardiometabolic conditions with significant unmet need. Leveraging our expertise in muscle biology and small molecule drug development, we are building a cardiovascular pipeline that includes programs for hypertrophic cardiomyopathy, heart failure and other serious cardiovascular diseases.

We’re building a passionate, experienced team committed to tackling complex scientific and clinical challenges and delivering meaningful outcomes for patients. If you’re looking to do work that matters, we’d love to hear from you.

About the Position:

Cardiovascular scientific leadership position, capable of both performing and leading multi-omics, molecular, in vitro, and in vivo scientific efforts. Broad range of responsibilities, including designing, managing, and overseeing high-quality experiments; establishing and managing internal and external collaborations; analyzing and communicating data; and contributing scientific insight to research activities that advance company objectives. The Associate Director/Director will provide strategic and scientific leadership for cardiovascular pharmacology programs and may be responsible for leading project teams and mentoring scientific staff.

Essential Job Duties and Functions:

Independently design, manage, and execute experiments in context of scientific goals across the company’s ongoing projects.
Conduct and/or manage a team that conducts detailed and complex wet laboratory experiments with appropriate technique and adequate controls satisfactory to substantiate/replicate results.
Contribute to the coordination and direction of research among the company’s scientific disciplines as they relate to assigned projects.
Manage a group of independent researchers.
Research and identify new opportunities and project ideas outside of assigned both the work and the company that complement the company’s mission, vision, values, and goals.
Establish appropriate objectives in the formulation of successful project strategy.
Influence the direction of company programs by designing experiments and collaborations, interpreting, analyzing, and correlating data from multiple sources, overcoming obstacles, and delivering results within project timelines.
Demonstrate a high level of resourcefulness through exceptional scientific knowledge and superior technical skills.
Actively increase team or group performance by critically reviewing work processes while offering insightful input and suggestions.
Produce and review individual and team scientific reports/presentations for internal and/or external purposes.
Work closely with consultants and collaborators to understand results and how they impact project goals.
Demonstrate a strong level of participation at project team meetings.
Maintain scientific records in clear required form.
Contribute advanced-level scientific perspective to patent efforts.
Update job knowledge by attending scientific meetings; participating in educational opportunities; reading professional publications; maintaining professional networks; and participating in professional organizations.
Read, understand, and comply with all workplace health and safety policies; safe work practices; and company policies and procedures.
Perform other duties as assigned by supervisor.

Required Education, Experience and Skills:

Ph.D. or equivalent experience in cardiovascular physiology or closely related field; post-doctoral and industry experience required.
8+ years of academic/research laboratory experience.
Exceptional understanding of scientific literature in respective area of science/research.
Demonstrated cardiovascular expertise (publication track record).
Technical expertise in both in vitro and in vivo cardiovascular techniques across a range of species, with strong molecular and multi-omics expertise.
Demonstrated ability to work independently and to lead independent scientists.
Familiarity with safe and efficient laboratory practices.
General scientific computer and software application proficiency.

Salary range: $185,000-$235,000, title and salary commensurate with experience

Our Benefits: We are proud to offer health benefits, a discretionary bonus plan, stock option grants. a stock purchase plan, a 401(k) with match and paid time off to our team members as part of their compensation plan.

There is no deadline because the employer accepts applications on an ongoing basis.

Edgewise does not accept resumes from recruitment agencies for this position. Please do not send resumes to Edgewise employees or the company location. Edgewise is not responsible for any fees related to unsolicited resumes.

About the Company

Edgewise Therapeutics

Develops therapies for rare muscular disorders

Edgewise Therapeutics develops therapies for rare muscle disorders using a proprietary drug discovery platform. Its lead molecule, sevasemten (EDG 5506), targets the muscle motor protein myosin to reduce stress in fast skeletal muscle fibers, aiming to improve muscle health without affecting other muscle types. The company owns global development and commercialization rights to its programs and pursues strategic collaborations and asset acquisitions to accelerate its pipeline. Its focus is precision medicine for conditions like Duchenne muscular dystrophy, Becker muscular dystrophy, Limb Girdle muscular dystrophies, and McArdle disease. Overall, Edgewise seeks to deliver targeted treatments that protect and improve muscle health for patients and families affected by these rare diseases.

Company size: 51-200
Company stage: IPO
Headquarters: Boulder, CO
Founded: 2017

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