Senior Scientist

Overview

Waters Corporation is seeking an accomplished scientific leader to oversee antibody and resin production in support of the VICAM® column production value stream. In this critical role, you will collaborate closely with Research & Development, Engineering, and Manufacturing teams to ensure the reliable, on-time production of antibodies and resins that meet quality, capacity, and operational requirements. The successful candidate will drive process excellence, optimize production performance, and ensure a consistent supply of key materials to support customer demand and the ongoing success of the column production line.

Responsibilities

Cell Culture Operations

• Retrieve, thaw, and initiate mammalian cell lines from cryogenic storage
• Monitor culture health, morphology, viability, and contamination status
• Perform routine passaging and expansion of cell cultures
• Maintain safety-stock cultures and frozen cell banks
• Perform sterile manipulations within biosafety cabinets

Seed Train Expansion

• Expand cultures through multiple vessel scales to generate inoculum
• Evaluate expansion readiness based on growth phase and culture condition
• Perform aseptic transfers, media additions, and feeding activities
• Maintain proper labeling and tracking of cultures

Bioreactor Setup & Operation

• Install and prepare single-use cultureware systems
• Perform system pressurization testing and leak checks
• Execute fill, flush, and priming procedures
• Perform bioreactor inoculation activities
• Monitor process parameters including temperature, pH, dissolved oxygen, and gas supply
• Collect in-process samples for routine analysis

 Cryopreservation & Cell Banking

• Harvest cultures for long-term storage
• Prepare freezing suspensions using appropriate cryoprotectants
• Aliquot into cryovials and perform controlled freezing steps
• Maintain cryogenic storage inventory and records 

Documentation & Compliance

• Maintain accurate batch records and laboratory documentation
• Record culture observations, process steps, and test results
• Follow established SOPs and aseptic handling procedures
• Adhere to safety and biosafety requirements 

Qualifications

Education & Qualifications

• Advanced degree in a relevant field — Bachelor Degree in Cell Biology, Molecular Biology, Bioengineering, Biotechnology, or related discipline required, MS preferred.
• Extensive research and development experience in cell culture, cell line development, or bioprocess engineering.
• Industry experience in biologics, cell therapy, or related manufacturing environments.
• Aseptic technique and sterile handling
• Mammalian cell culture fundamentals
• Laboratory safety and biosafety practices
• Basic bioreactor operations
• Microscopy and culture assessment
• Accurate record keeping and documentation
• SAP ERP Systems

Company Description

Waters Corporation (NYSE:WAT)  is a global leader in life sciences and diagnostics, dedicated to accelerating the benefits of pioneering science through analytical technologies, informatics, and service. With a focus on regulated, high-volume testing environments, our innovative portfolio harnesses deep scientific expertise across chemistry, physics, and biology. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Through a shared culture of relentless innovation, our passionate team of ~16,000 colleagues turn scientific challenges into breakthroughs that improve lives worldwide.  

Diversity and inclusion are fundamental to our core values at Waters Corporation. It benefits our employees, our products, our customers and our community. Waters complies with all applicable federal, state, and local laws. Qualified applicants are considered without regard to sex, race, color, ancestry, national origin, citizenship status, religion, age, marital status (including civil unions), military service, veteran status, pregnancy (including childbirth and related medical conditions), genetic information, sexual orientation, gender identity, legally recognized disability, domestic violence victim status, or any other characteristic protected by law. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. All hiring decisions are based solely on qualifications, merit, and business needs at the time.

Key Words

Cell culture, Materials Science, Particle Synthesis, Organic Chemistry