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Axle

Translational research informatics and data science

Biologist – Mass Spectrometry

Full-TimeUpdated on 10/23/2026
$95k - $110k+ Employee referral bonus + 401(k) match
Mid, Senior
Master's, PhD
Rockville, MD, USA
In Person
Biology & BiotechBioprocess & Biomanufacturing

About the job

Requirements
  • A Ph.D. in mass spectrometry, analytical chemistry, biochemistry, chemistry, pharmaceutical sciences, or a related scientific discipline with one to two years of relevant pharmaceutical or biotechnology industry experience applying mass spectrometry to characterize biomolecules and quantify molecules of interest, or a master's degree in a related scientific discipline with four to five years of relevant pharmaceutical or biotechnology industry experience.
  • Demonstrated hands-on experience with mass spectrometry and liquid chromatography-mass spectrometry-based analytical techniques for analysis of biologic molecules.
  • Experience with quantitative and/or qualitative analytical methods used to characterize proteins, antibodies, vaccines, or other biologic products.
  • Working knowledge of analytical method development, optimization, troubleshooting, and data interpretation.
  • Ability to work independently on assigned activities, exercise scientific judgment, troubleshoot experimental issues, and proactively communicate findings and challenges.
  • Ability to take ownership of assigned work while functioning effectively as part of a scientific team.
  • Ability to collaborate with scientists and members of cross-functional groups.
  • Ability to maintain accurate and detailed laboratory records and scientific documentation.
  • Analytical, problem-solving, organizational, oral communication, and written communication skills.
  • Ability to manage multiple assignments and priorities in a fast-paced research and development laboratory environment.
  • Familiarity with computer software used for scientific data acquisition, analysis, visualization, documentation, and presentation.
Responsibilities
  • Perform analytical development activities to characterize and quantify biologic products, including vaccines, monoclonal antibodies, recombinant proteins, and other biologic modalities.
  • Use mass spectrometry to characterize and quantify biologic molecules in support of vaccine and other biologics development programs.
  • Perform and support liquid chromatography-mass spectrometry-based analytical testing, including sample preparation, data acquisition, data analysis, interpretation, and documentation of results.
  • Execute established analytical methods and contribute to development, optimization, qualification, troubleshooting, and transfer of new or existing analytical methods.
  • Analyze and interpret experimental data using scientific judgment; identify trends, technical issues, and unexpected results; and contribute to investigations and troubleshooting activities.
  • Support Bioseparations within Analytical Development by performing electrophoresis-based analytical techniques to separate and characterize biologic molecules.
  • Work independently on assigned laboratory activities while collaborating with senior scientists and multidisciplinary project team members.
  • Maintain complete experimental records and prepare technical documentation, summaries, and presentations of analytical results.
  • Communicate experimental results, technical observations, and potential issues to project teams and participate in internal scientific and project meetings.
  • Support multiple development projects and prioritize assigned laboratory activities to meet project timelines.
  • Contribute to continuous improvement of analytical workflows and identify opportunities to improve assay performance, robustness, efficiency, and data quality.
  • Collaborate across Analytical Development and with other VPP functional groups to support project objectives.
Desired Qualifications
  • Experience with electrophoresis-based analytical techniques for protein/biologic separation and characterization.

About the company

Axle Informatics provides specialized informatics solutions for translational research, health informatics, and data science to biomedical research centers and healthcare organizations. Its offerings are customized software and data management platforms that help researchers collect, integrate, analyze, and visualize large research datasets, with end-to-end tools that automate data aggregation and deliver analytics, dashboards, and decision-support features. The company differentiates itself with an integrated, scientifically informed approach that bridges data science with application development, specifically focused on translational research and clinical data work rather than generic software. Axle’s goal is to advance public health by moving biomedical discoveries from the lab to bedside, improving healthcare outcomes.

Company Size

201-500

Company Stage

N/A

Total Funding

N/A

Headquarters

Rockville, Maryland

Founded

2002

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Simplify's Take

What believers are saying

  • Axle secured a $21 million NCATS support contract starting February 2025.
  • Axle won a 2026 NHLBI systems biology task for single-cell genomics work.
  • Axle’s May 2026 NIH and SK pharmteco partnership expands credibility in rare-disease gene therapy.

What critics are saying

  • NIH concentration makes Axle vulnerable if NCATS and NHLBI rebid work in 2026.
  • Axle filed and lost GAO protests in August 2026, signaling procurement pressure.
  • Federal budget lapses instantly freeze specialized scientific services; Axle’s core contracts depend on appropriated NIH funding.

What makes Axle unique

  • Axle Informatics won NIH NCATS and NHLBI work in 2025-2026.
  • Axle combines biomedical staff scientists, cloud engineering, and translational research program management.
  • Axle’s NIH foothold includes rare-disease gene therapy collaboration with SK pharmteco, May 2026.

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Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Paid Vacation
  • Paid Holidays
  • 401(k) Company Match
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts

Company News

TheGWW.com
Jul 25th, 2023
“Octo awarded $64.7M IT Infrastructure Call Order to support NCI’s Cancer research”

Octo, in partnership with Unissant, Axle Informatics, and TRex, has been awarded an IT Infrastructure and Operations Call Order to support the NCI’s OCIO.

GlobeNewswire
Jan 12th, 2023
Digital Pathology Market Worth $1.86 Billion by 2030 -

For instance, in May 2020, Indica Labs (U.S.), a provider of digital pathology solutions, collaborated with information technology consulting companies, Octo (U.S.) and Axle Informatics (U.S.) and the National Institutes of Health (NIH) (U.S.), to develop an online collection of high-resolution histopathology images of tissues from COVID-19 patients using Indica’s HALO Link platform.