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CluePoints

Cloud-based RBQM platform for clinical trials

Principal Data Platform Architect

Full-TimeUpdated on 10/23/2026
No salary listed
Expert
Belgium
HybridHybrid, hub-based work in Belgium.
Software EngineeringBackend Engineering

About the job

Requirements
  • Has built and evolved a metadata-driven or schema-flexible data platform in production.
  • Currently writes production code.
  • Applies audit-grade thinking to data lineage, versioning, and attributable change in any regulated domain.
  • Can describe experience managing schema drift in production, including what broke and what was changed.
  • Separates structural mapping from semantic meaning in data design.
  • Uses artificial intelligence tools in day-to-day delivery with explicit verification and evaluation of their output.
  • Has a track record of coaching engineers through code.
  • Can design for the available team, with scope sized to a small squad.
  • Communicates architecture clearly to engineering, quality assurance, and business leadership.
Responsibilities
  • Own the design of the CluePoints data layer and build it hands-on, writing production code alongside the squad.
  • Design a metadata-driven schema with a stable spine that absorbs change without breaking the applications built on it.
  • Build a semantic tier that maps study fields to concepts, keeping structure and meaning cleanly separate.
  • Deliver a versioned, auditable query interface for applications, with lineage and attributable change built in.
  • Set the squad’s engineering and artificial intelligence-first practices, using artificial intelligence tools with clear verification and evaluation.
  • Coach engineers through code and design, and partner with the general manager and vice president of engineering on direction.
Desired Qualifications
  • Experience with multi-tenant software as a service and strong data segregation.
  • Background in semantic layers, ontologies, knowledge graphs, or schema and ontology matching.
  • Familiarity with clinical and health data standards such as CDISC, ODM, FHIR, or OMOP, or with GxP and 21 CFR Part 11; clinical knowledge can be learned on the job.
  • Visible hands-on work, such as recent open-source commits, contributions to projects like OpenLineage, DataHub, Iceberg, HAPI FHIR, or OHDSI, or conference talks.

About the company

CluePoints provides risk-based quality management and data quality oversight software for clinical trials. Its cloud-based platform analyzes trial data using advanced statistics, machine learning, and AI to identify risks and monitor data quality from initial risk assessment through issue tracking. Key products—Site Profile and Oversight Tool (SPOT), Intelligent Medical Coding (IMC), Intelligent Query Detection (IQD), and Medical & Safety Review (MSR)—automate data discrepancy detection, improve medical review efficiency, reduce manual coding, and enable adaptive site monitoring. The company differentiates itself with an end-to-end, multi-product platform (expanded in 2024) that combines RBQM, data analytics, and regulatory-aligned monitoring to help pharmaceutical/biotech companies and CROs de-risk trials and ensure data integrity and patient safety. Its goal is to help customers meet regulatory guidance from bodies like the FDA and EMA while improving trial quality and efficiency.

Company Size

201-500

Company Stage

Acquired

Total Funding

$6.6M

Headquarters

Ottignies-Louvain-la-Neuve, Belgium

Founded

2012

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Benefits

  • Health Insurance
  • Wellness Program
  • Gym Membership
  • Hybrid Work Options
  • Professional Development Budget

Growth & Insights and Company News

6 month growth

0%

1 year growth

0%

2 year growth

4%
PR Newswire
Jul 27th, 2026
CluePoints appoints Martin Magazzolo as chief commercial officer

CluePoints, a provider of statistical and AI-driven software solutions for clinical trials, has appointed Martin Magazzolo as chief commercial officer. Magazzolo brings over 30 years of executive leadership experience in life sciences and healthcare technology, joining from Honeywell where he served as chief commercial officer for the company's life sciences business unit. He succeeds co-founder Pat Hughes, who is transitioning to a strategic advisor role. Magazzolo will lead CluePoints' global commercial organisation, including sales, marketing, and account management, as the company scales its Risk-Based Quality Management and clinical data quality oversight solutions. CluePoints uses advanced analytics and machine learning to assess clinical trial data quality and integrity, supporting regulatory compliance with FDA, EMA, and ICH guidance.

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Clinical Research News
Jan 21st, 2026
CluePoints Appoints New Chief People Officer to Support Next Phase of Global Growth

CluePoints appoints new Chief People Officer to support next phase of global growth. CluePoints, provider of leading statistical and AI-driven software solutions, has appointed Sinead Godkin as its new Chief People Officer (CPO). King of Prussia, PA - January 20, 2026 - CluePoints, provider of leading statistical and AI-driven software solutions, has appointed Sinead Godkin as its new Chief People Officer (CPO). With deep experience scaling global technology organizations through periods of rapid growth, Godkin will lead CluePoints' people strategy as the company enters its next stage of expansion. Godkin brings senior leadership experience from some of the world's leading technology companies. Most recently, she served as Chief People Officer at DigiCert, where she was a key member of the executive team, supporting the scale-up of a private equity owned organization and leading enterprise-wide people transformation during periods of accelerated growth and acquisition. Earlier in her career, she held senior leadership roles at Veritas Technologies and Symantec, building deep expertise in global workforce strategy within complex, multinational environments. Andy Cooper, CEO at CluePoints, commented: "People are our most important asset at CluePoints and in 2025 we recruited more than 100 new team members. As we continue to grow, it is vital we maintain the same culture of care and development that CluePoints is built on. Sinead brings a rare combination of international experience, commercial insight, and a deep understanding of how to scale people and teams in a fast-growing software business." In her role, Godkin will lead the evolution of CluePoints' people organization, ensuring it is equipped to support increasing global complexity, rapid growth, and organizational scale and sophistication as the company continues to expand internationally. Sinead Godkin added: "CluePoints is at an exciting point in its history, scaling globally, evolving rapidly, and continuing to push the boundaries of how technology can improve clinical research. I'm excited to build on the strong culture already in place and to help create the leadership, development, and people frameworks that enable both individuals and the organization to thrive as we scale." As part of CluePoints' broader commitment to innovation, Godkin will also explore how emerging technologies, including AI-enabled tools, can support more effective, scalable ways of working, ensuring that growth is matched by clarity, efficiency, and opportunity for employees. To learn more about CluePoints' award-winning solutions, please visit cluepoints.com About CluePoints CluePoints is the premier Risk-Based Quality Management (RBQM) and Data Quality Oversight Software provider. Clinicalresearchnewsonline is leveraging the potential of Artificial Intelligence using Advanced Statistics and Machine Learning to determine the quality, accuracy, and integrity of clinical trial data both during and after study conduct. Aligned with guidance from the FDA, EMA, and ICH E6 (R3), CluePoints is deployed to support central and on-site monitoring, medical review, quality risk management and to drive a holistic Risk-Based strategy in all trials. Coupled with thought leadership and consulting expertise to aid pre-study risk assessment, identification of risk controls and solution implementation, you now have everything you need to adhere with global regulatory guidance. The result is positive clinical development outcomes, increased operational efficiency, lower costs and reduced regulatory submission risk as part of the industry paradigm shift to RBQM.

PharmiWeb
Jun 3rd, 2025
Industry Leading Rbqm Event Returns For 2025

Industry Leading RBQM Event Returns for 2025Expert Speaker Lineup announced for CluePoints Sponsored RBQMLive 2025King of Prussia, PA – June 3, 2025: CluePoints, the premier sponsor of RBQMLive and provider of leading statistical and AI-driven software solutions, has announced the full agenda and expert speaker line up for the 4th annual, award-winning event, RBQMLive.RBQMLive, taking place on Thursday, September 25th, 2025, is a free virtual event, that unites industry experts, clinical trial specialists, and the wider industry to share insights, education and discuss the acceleration of RBQM. The free event will profile discussions on the return on investment of RBQM, the impact of recent regulatory updates and the implementation of AI.Following the success of last year’s event, which drew in over 1,500 attendees from more than 290 organizations, RBQMLive 2025 is set to deliver even greater value with fresh opportunities and practical learning.Highlights from RBQMLive 2025 will include:A keynote address from Ken Getz, Executive Director and Professor, and Abigail Dirks, Data Scientist, Tufts Center for the Study of Drug Development. Key topics discussed will include the fundamentals of RBQM and net present value (NPV) analysis, understanding how the principles of ICH E6(R3) align with RBQM, the measurable financial and operational benefits of RBQM implementation and practical strategies for implementing RBQM into organizations. Ken Getz and Tufts CSDD will also present new data modeling that provides a comprehensive analysis of the ROI of RBQM.from Ken Getz, Executive Director and Professor, and Abigail Dirks, Data Scientist, Tufts Center for the Study of Drug Development. Key topics discussed will include the fundamentals of RBQM and net present value (NPV) analysis, understanding how the principles of ICH E6(R3) align with RBQM, the measurable financial and operational benefits of RBQM implementation and practical strategies for implementing RBQM into organizations. Ken Getz and Tufts CSDD will also present new data modeling that provides a comprehensive analysis of the ROI of RBQM

Clinical Research News
Apr 16th, 2025
CluePoints' Technology Named as Finalist in 2025 Citeline Awards

King of Prussia, PA - April 15th, 2025: CluePoints, provider of leading statistical and AI-driven software solutions, has been named as a finalist in the 'Innovative Clinical Trial Solutions' category at the 2025 Citeline Awards.