Full-Time

Principal Scientist-LCMS

Posted on 11/23/2025

Altasciences

Altasciences

1,001-5,000 employees

Integrated CRO for early-phase drug development

No salary listed

Columbia, MO, USA

In Person

Category
Biology & Biotech (2)
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Requirements
  • Advanced Expertise: Whether you hold a Bachelor's, Master's, or PhD in biological, Biochemistry, pharmaceutical science, you'll bring a wealth of knowledge and experience to the table, backed by years of hands-on experience in performing laboratory-based assays related to immunology, molecular biology, and/or cell biology/ biochemistry/chemistry.
  • Supervisory Skills: While previous supervisory experience is a plus, we welcome candidates who are eager to step into leadership roles and make a difference in our dynamic team environment.
  • Technological Savvy: From advanced computer skills to familiarity with LIMS and electronic notebooks, you'll leverage the latest tools and technologies to drive innovation and efficiency.
  • Communication Mastery: Your ability to communicate complex scientific concepts with clarity and precision will be essential as you collaborate with colleagues and engage with clients.
  • Ideally minimum 5 years as Senior Scientist or equivalent.
Responsibilities
  • Demonstrates adherence to Good Laboratory Practices (GLP).
  • Supervises lab personnel as assigned.
  • Plans, schedules activities and resources related to preparation and execution of specimen analysis.
  • Oversees and reviews data to ensure accuracy, completeness, consistency and compliance.
  • Reviews and responds to client inquiries to assist in study and assay design.
  • Prepares and modifies SOPs as needed for the Laboratory Sciences department.
  • Prepares, reviews and participates in the validation/qualification of new and current methods for study analyses and laboratory equipment.
  • Supervises and assists with analytical quality control and lab proficiency programs as assigned.
  • Provide staff training in relevant methods and equipment use.
  • Review staff records to ensure compliance with GLP

Altasciences provides an integrated CRO that handles the full early‑phase drug development path, from preclinical testing through clinical proof of concept and into manufacturing. Its approach combines discovery support, safety testing, clinical trial execution, and in‑house manufacturing to run programs under one roof. This contrasts with competitors that require pharma and biotech clients to source services from multiple vendors, adding complexity and risk; Altasciences streamlines the process by coordinating all steps. The company aims to help innovator drug programs move quickly and efficiently, delivering integrated data to de‑risk decisions and speed progression to later stages.

Company Size

1,001-5,000

Company Stage

Early VC

Total Funding

$6.7M

Headquarters

Laval, Canada

Founded

1976

Simplify Jobs

Simplify's Take

What believers are saying

  • Biotech/pharma consolidation demand for single-vendor early-phase development solutions increases.
  • 3D tissue technology adoption reduces animal testing costs and accelerates regulatory approval timelines.
  • Geographic footprint and participant database enable rapid enrollment for mid-size biopharma sponsors.

What critics are saying

  • Novo Holdings divesting Altasciences signals poor financial performance and operational cutbacks.
  • Charles River aggressive pricing on integrated packages captures 20% mid-size biopharma contracts.
  • AI-driven preclinical platforms from Insilico Medicine displace traditional animal safety pharmacology testing.

What makes Altasciences unique

  • Integrated CRO/CDMO spanning preclinical safety testing through Phase IV bioanalysis and manufacturing.
  • 9 North American facilities with 500,000+ participant database conducting 285+ trials annually.
  • VoxCell partnership integrates 3D tissue technology for human-relevant preclinical testing.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

401(k) Company Match

Paid Vacation

Paid Sick Leave

Paid Holidays

Employee Assistance & Telehealth Programs

Remote Work Options

Company News

GlobeNewswire
Mar 16th, 2026
Outlook Therapeutics Announces New $18.4 Million Non-Convertible Note Financing and Amendment to Existing Convertible Note

ISELIN, N.J., March 16, 2026 (GLOBE NEWSWIRE) -- Outlook Therapeutics, Inc. (Nasdaq: OTLK), a biopharmaceutical company focused on enhancing the standard...

Business Wire
Aug 20th, 2025
Altasciences Receives EcoVadis Gold Medal for Environmental, Social, and Governance (ESG) Efforts

EcoVadis, the world's most trusted provider of business sustainability ratings, has collaborated closely with Altasciences to enhance its environmental, social, and governance (ESG) initiatives, underscoring the company's commitment to a sustainable future and a reduced environmental footprint.

Yahoo Finance
Jul 31st, 2025
Altasciences and VoxCell BioInnovation Announce Strategic Collaboration to Advance Preclinical Drug Development

This partnership combines Altasciences' comprehensive early-phase drug development capabilities with VoxCell's cutting-edge 3D tissue technology to offer a more predictive and human-relevant preclinical testing environment.

Postmedia Network
Mar 28th, 2025
Altasciences Receives 2025 CDMO Leadership Award in Small Molecule Dosage Form Category

For 14 years, Outsourced Pharma's CDMO Leadership Awards have recognized the top-performing contract development and manufacturing organizations based on comprehensive industry research, and feedback from sponsors.

BioSpace
May 29th, 2024
Altasciences Receives 2024 CRO Leadership Award for Capabilities

Altasciences receives 2024 CRO Leadership Award for Capabilities.

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