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Element Biosciences

Low-cost next-generation DNA sequencing technology

Staff Scientist - Surface Chemistry

Biomedical Engineering & Medical DevicesConfirmed live in the last 24 hours
Full-timeSan Diego, CA, USAIn-person

About the Job

Requirements

  • A PhD in chemistry, materials science, biochemistry, bioengineering, physics, or a related field is required.
  • At least 6 years of relevant industry experience in surface chemistry, materials science, or biomolecular interfaces in life sciences or diagnostics is required.
  • A strong publication and presentation record, with contributions to patents or novel methods, is required.
  • Deep expertise in surface chemistry, polymer chemistry, and biomolecule–surface interactions is required.
  • A background in next-generation sequencing, genomics, proteomics, or multiomics platforms is required.
  • Familiarity with manufacturing constraints, process transfer, or scale-up is required.
  • Ability to plan and execute experiments and interpret data independently, with minimal day-to-day supervision, is required.
  • Ability to apply scientific judgment to address novel or ambiguous technical challenges is required.
  • Ability to identify risks, knowledge gaps, and opportunities and propose data-driven approaches that shape project scope and organizational priorities is required.
  • Ability to lift up to 20 pounds is required.
  • Ability to handle chemicals and follow laboratory safety protocols, including familiarity with personal protective equipment, is required.

Responsibilities

  • Design, develop, and evaluate novel surface chemistry approaches for next-generation sequencing and multiomics applications.
  • Design and evaluate surface chemistry solutions on microfluidic and lab-on-chip devices, considering how device geometry and flow conditions affect surface performance and assay outcomes.
  • Define and lead product development efforts, including experimental design, prototyping, functional testing, and data analysis.
  • Troubleshoot performance issues related to surface fouling, non-specific binding, or cell compatibility.
  • Identify and resolve experimental challenges involving assay design, protocol execution, reagent selection, and surface performance.
  • Support transfer of surface chemistry solutions from research into product development and manufacturing, collaborating with process development and operations teams.
  • Provide hands-on scientific leadership by setting the direction for laboratory experimentation and troubleshooting, mentoring junior scientists, and guiding their technical development.
  • Contribute ideas and technical insight to early-stage concept development and feasibility assessments.
  • Contribute technical expertise to invention disclosures and patent applications in collaboration with the intellectual property legal team and senior technical leadership.
  • Collaborate with product management, assay development, engineering, and manufacturing colleagues to align work and ensure successful execution.
  • Prepare and deliver technical reports and presentations that summarize findings, support decision-making, and document development progress.

Desired Qualifications

  • Familiarity with microfluidic device design principles, including how channel geometry, surface-to-volume ratios, and flow dynamics influence surface chemistry performance and assay outcomes.
  • Experience with device fabrication, such as soft lithography or PDMS, or working with commercial lab-on-chip platforms.
  • Familiarity with surface analytical techniques such as AFM, ellipsometry, FTIR, SEM, TOF-SIMS, and XPS.

About the Company

Element Biosciences

Low-cost next-generation DNA sequencing technology

Element Biosciences offers the AVITI System, a compact benchtop sequencing platform that provides high-accuracy DNA sequencing at a low cost. The system delivers sequencing data on a small instrument and can be integrated into workflows through partners like QIAGEN, enabling complete NGS solutions. It differentiates itself with a low per-read price of $1 per million reads, strong ecosystem partnerships, and initiatives like the AVITI for All Grant that funds free sequencing. Its goal is to make DNA sequencing more affordable and accessible for academic and industry customers, helping more projects fit within tighter budgets.

Company size
201-500
Company stage
Series E
Total funding
$853M
Headquarters
San Diego, CA
Founded
2017

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