Generation Bio is innovating non-viral genetic medicines to provide durable and redosable treatments for hundreds of millions of patients living with rare and prevalent diseases. The company is developing two distinct and complementary platforms: a potent, highly selective cell-targeted lipid nanoparticle (ctLNP) delivery system and a novel immune-quiet DNA (iqDNA) cargo produced by a scalable capsid-free manufacturing process that uses proprietary cell-free rapid enzymatic synthesis (RES). With these platforms, Generation Bio aims to develop the next wave of non-viral genetic medicines to support its mission to extend the reach of genetic medicine to more people living with more diseases, around the world.
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Generation Bio is seeking an energetic and highly motivated Associate Director/Principal Scientist to join the Immunology Group. The position will play a key role in development and evaluation of our cell targeted lipid nanoparticle (ctLNP) delivery platform by devising and executing a strategic plan aimed at evaluating ctLNPs interacting with immune cells. The successful candidate will have a depth of experience performing in vitro experiments with primary human immune cells and assay development. The candidate will support the execution and provide direction to scientists conducting vitro PoC and MOA assays using human and/or murine immune cells to further facilitate evaluation of ctLNP and novel target biologies. The ideal candidate will have experience executing in vivo small animal pharmacology studies related to the exploration of immunology in areas of disease related to immunology such as oncology or autoimmunity. The candidate is expected to have a firm grasp of human T cell biology and the design and analysis of complex multicolor flow cytometry endpoints. The candidate will have strong communication skills and be adept at working cross functionally and collaboratively with scientists and stakeholders.
EEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race (to include traits historically associated with race including, but not limited to, hair texture, hair type, hair length, and protective hairstyles such as braids, locks, twists, hair coverings, and Bantu knots), color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.