Full-Time

Director – Platform Chemistry

Flagship Pioneering

Flagship Pioneering

501-1,000 employees

Originates biotech ventures for health and sustainability

Venture Capital

Senior, Expert

Cambridge, MA, USA

Requirements
  • PhD in organic chemistry
  • 10+ years relevant pharmaceutical experience
  • Experience in building, maintaining, and as needed adjusting high performing teams
  • Experience managing offshore CRO chemistry maximizing for quality, efficiency, and value creation
  • A clear command of classical and modern synthetic methodologies relevant to 21st-century drug discovery
  • Direct experience with or well informed of modern covalent chemistry across the full range of reactive amino acids
  • Clearly demonstrable experience in the discovery of orally bio-available beyond rule-of-5 small molecules including PROTACs and other heterobifunctional molecules
  • Deep understanding of the interplay between chemistry and multiparameter SAR development
  • Maximizing ML’s impact on lead identification and advancement
  • Track record of DC nominations à INDs à clinical stage drug candidates
  • Passionate innovator solving today’s problems and creating tomorrow’s opportunities
  • Strategic thinker and planner consistent with the business, science, and innovation needs of FL94
  • Thought leader and functional representative in a multi-functional environment tasked with creating first or best in class small molecule protein editors
  • Clear communicator, authentic leadership qualities, open to take and give feedback up, down and across the organization
Responsibilities
  • Developing and executing on the generative covalent chemistry platform including screening library generation, ML integration, hit ID, and validation, and rapid progression of hits to pivotal in vitro and in vivo PoC compounds.
  • Building, maintaining, and as needed adjusting high performing teams.
  • Managing offshore CRO chemistry maximizing for quality, efficiency, and value creation.
  • Strategic thinking and planning consistent with the business, science, and innovation needs of FL94.
  • Being a thought leader and functional representative in a multi-functional environment tasked with creating first or best in class small molecule protein editors.
  • Communicating clearly, authentic leadership qualities, open to take and give feedback up, down and across the organization.

Company Stage

N/A

Total Funding

$6.4B

Headquarters

Cambridge, Massachusetts

Founded

2000

Growth & Insights
Headcount

6 month growth

9%

1 year growth

24%

2 year growth

48%
INACTIVE