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Adaptyv Biosystems

AI-driven wet lab for protein design

Scientist – Binding Kinetics

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeLausanne, SwitzerlandNo salary listedIn-person

About the Job

Requirements

  • MSc or PhD in biochemistry, biophysics, or a relevant field, plus 3+ years of hands-on binding kinetics experience.
  • Deep experience with SPR and BLI, including running and troubleshooting assays and interpreting substantial amounts of data; experience with Biacore, Carterra, Octet, or Gator is relevant.
  • Apply fitting judgment across 1:1 and bivalent models, determine when steady-state analysis is appropriate, understand how mass transport and avidity distort results, and defend or withhold reporting a Kd as warranted.
  • Use Python or R to retrieve hundreds of results from a database, fit and plot the data, and identify outliers.
  • Work independently to prioritize tasks and carry them out without a daily prioritized queue.
  • Become productive quickly with unfamiliar tools as the platform, assays, and software change.
  • Meet customer deadlines in a startup environment and flag ambiguous results rather than delaying them.
  • Be comfortable discussing results with customers, including PhD-level scientists at pharmaceutical companies and AI labs, and responding to challenges.
  • Explain technical concepts clearly to both biophysicists and machine-learning researchers without condescension.
  • Communicate uncertainty honestly and flag weak or ambiguous results rather than presenting them as certain.

Responsibilities

  • Review binding data from SPR and BLI runs after pipeline processing, decide what is delivered or flagged, and determine what must be rerun.
  • Evaluate curves and fits, distinguishing genuine off-rates and two-state binding events from fit artifacts and drifting baselines.
  • Review data from thermostability, expression, developability, and enzyme activity assays.
  • Discuss customer results through deliverable walkthroughs and follow-up conversations, explain measurements and confidence, and advise on next steps.
  • Design changes for reruns, including orientation, regeneration, concentration series, or switching between BLI and SPR for sensitivity.
  • Analyze results at batch level using scripts to identify patterns such as systematic drift, bad reference channels, or differences in target lots.
  • Provide concrete software requirements based on cases where automation incorrectly passed or failed a result.
  • Work closely with production, quality control, and customer success teams.

Desired Qualifications

  • Familiarity with other biophysical or functional assays, including DSF, HPLC, and plate-based activity assays.

About the Company

Adaptyv Biosystems

AI-driven wet lab for protein design

Adaptyv Biosystems builds an automated, AI-native wet lab for protein design validation. Customers submit digital protein sequences via web or API; Adaptyv synthesizes DNA, expresses proteins in a cell-free system, and measures binding with SPR, delivering validated experimental data through an API-ready workflow. The platform offers end-to-end automation and direct integration with AI and lab software, enabling scale beyond traditional lab capacity. Its goal is to close the gap between AI-designed proteins and experimental validation, expand lab throughput, and support customers from frontier AI labs to large pharma.

Company size
11-50
Company stage
Series A
Total funding
$48.5M
Headquarters
Lausanne, Switzerland
Founded
2020

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