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Dyne Therapeutics

Develops muscle-disease therapies using FORCE platform

Senior Manager - US Medical Affairs

Biology & BiotechConfirmed live in the last 24 hours
Full-timeWaltham, MA, USA$165k - $190k

About the Job

Requirements

  • An advanced scientific or clinical degree (PhD, PharmD, MD, or equivalent) is required.
  • At least 7 years of relevant Medical Affairs experience in the pharmaceutical or biotechnology industry is required.
  • Experience supporting US-based medical tactics, congress activities, or field medical programs is required.
  • Strong scientific acumen and the ability to translate clinical data for diverse audiences are required.
  • Strong written and verbal communication skills are required.
  • Ability to operate effectively in a fast-paced, evolving environment with competing priorities is required.
  • Demonstrated ability to build collaborative relationships with internal and external stakeholders is required.
  • Ability to travel up to 25%, including occasional overnight and weekend travel, is required.

Responsibilities

  • Support execution of US Medical Affairs tactical plans for the Duchenne muscular dystrophy program.
  • Assist in implementing scientific platform materials, congress planning, and medical education initiatives.
  • Contribute to cross-functional launch readiness activities to ensure alignment with program milestones.
  • Support development and deployment of Duchenne-focused scientific materials, disease-state education resources, and field medical tools.
  • Partner with the US Medical Science Liaison team to support key opinion leader identification, engagement planning, insight gathering, and field metric tracking.
  • Translate field insights into actionable recommendations for Medical Affairs and cross-functional teams.
  • Track and monitor field activity and engagement effectiveness.
  • Contribute to development of scientific materials, field tools, and educational content.
  • Provide Medical review for promotional materials through the Promotional Review Committee.
  • Maintain deep and current scientific knowledge in Duchenne muscular dystrophy and Dyne’s therapeutic platform.
  • Support planning and execution of medical congresses, including onsite activities aligned to Duchenne program milestones.
  • Coordinate logistics and execution of US advisory boards and expert engagements.
  • Partner with Patient Advocacy, Market Access, and Commercial teams to support aligned medical activities.
  • Ensure all activities comply with US regulatory, legal, and compliance standards.

Desired Qualifications

  • Rare disease experience is preferred; neuromuscular disease experience is a plus.

About the Company

Dyne Therapeutics

Develops muscle-disease therapies using FORCE platform

Dyne Therapeutics develops therapies for serious muscle diseases using its FORCE™ platform, which helps deliver oligonucleotide medicines to muscle tissue. Through a portfolio of experimental therapies, the company advances them in clinical trials (ACHIEVE and DELIVER) with the aim of treating rare muscle diseases. The product works by enhancing targeted delivery of oligonucleotides to muscle, enabling existing genetic medicines to reach affected tissues more effectively. Dyne differentiates itself by its proprietary FORCE™ technology and its focus on rare muscle diseases, positioning itself for growth as trials progress toward potential commercialization. The company’s goal is to bring effective treatments to patients and families affected by serious muscle diseases, expanding options as its therapies advance through development and, potentially, regulatory approval.

Company size
201-500
Company stage
IPO
Headquarters
Waltham, MA
Founded
2017

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