Full-Time

Sr. Research Associate/ – Sr

Associate Scientist, Synthetic Biology

Posted on 5/6/2024

Shape Therapeutics

Shape Therapeutics

51-200 employees

Develops programmable RNA medicines using AI

AI & Machine Learning
Data & Analytics

Senior

Cambridge, MA, USA

Requirements
  • B.S. degree in a relevant scientific discipline with 4+ years of experience in a laboratory setting, or an M.S. with 2+ years experience in a laboratory setting.
  • Experience with molecular biology techniques: DNA / RNA purification; PCR amplification and sequencing; plasmid design and cloning.
  • Experience with mammalian cell culture and transfection, particularly cell line engineering using CRISPR/Cas9 nucleases, base editors, integrases, transposons, or viral transduction.
  • Preferred experience in production of Adeno-Associated Virus vectors for gene therapy.
  • Preferred experience in next-generation sequencing, droplet digital PCR, automated liquid handling, flow cytometry staining, and/or single-cell cloning.
  • Attention to detail, meticulous sterile technique, diligent record-keeping, organization, and time management
  • An interest in technology development, learning new techniques, and inventing novel methods.
Responsibilities
  • Genetically engineer immortalized mammalian cell lines and characterize quantitative and qualitative improvements to AAV production.
  • Design and plan well-controlled experiments. Seek opportunities to innovate and improve current protocols and workflows. Troubleshoot as needed to find creative solutions.
  • Assist with lab operations as needed (setting up new lab space, consumables ordering, equipment maintenance) and generally being a good lab citizen.
  • Support and collaborate on multiple projects in a fast-paced startup environment, working across teams at ShapeTx.
  • Interpret and communicate results to team members to drive key decisions and future experiments.

At Shape Therapeutics Inc., employees are at the forefront of pioneering programmable RNA medicines, using cutting-edge AI and RNA technologies. The company's strong focus on developing treatments for a broad spectrum of diseases, including rare genetic disorders and neurodegenerative conditions, positions it as a leader in the biotechnology field. The integration of AI with advanced RNA and gene therapy technologies not only fosters an environment of technical innovation but also enhances its competitive edge in creating impactful medical solutions.

Company Stage

Series B

Total Funding

$147.5M

Headquarters

Seattle, Washington

Founded

2018

Growth & Insights
Headcount

6 month growth

8%

1 year growth

19%

2 year growth

36%