M

Mineralys Therapeutics

Clinical-stage biopharma targeting aldosterone synthesis

Territory Manager

Full-Time
$130k - $165k+ Performance-based incentive plans
Mid
Bachelor's
Remote in USA
RemoteRequires up to 60% travel within the assigned territory.
Sales & Account ManagementField Sales

About the job

Requirements
  • A bachelor's degree or equivalent experience is required.
  • A proven track record of achieving or exceeding sales goals and building strong customer relationships.
  • Strong clinical acumen and the ability to communicate complex scientific information.
  • Excellent territory planning, organizational, and communication skills.
  • A self-motivated, entrepreneurial mindset and the ability to thrive in a fast-paced launch environment.
  • A valid driver's license and willingness to travel within the territory.
Responsibilities
  • Develop and maintain a strong understanding of the disease state, clinical data, and relevant treatment guidelines.
  • Build and execute a comprehensive territory business plan aligned with brand strategy, launch priorities, and sales objectives.
  • Drive product adoption and compliant utilization among targeted healthcare providers.
  • Analyze territory trends, customer needs, and competitive activity to identify opportunities and course-correct as needed.
  • Consistently deliver against sales goals, call activity expectations, and launch milestones.
  • Maintain accurate territory reporting and customer relationship management documentation.
  • Execute strategic call plans by translating data and insights into impactful, customer-focused actions.
  • Build and sustain trusted relationships with healthcare providers, office staff, and key decision-makers.
  • Clearly and compliantly communicate clinical data, product value, access information, and appropriate patient identification.
  • Deliver engaging, high-quality product presentations and address customer questions with confidence and credibility.
  • Partner with customers to address barriers to patient access and support product pull-through.
  • Partner effectively with cross-functional stakeholders to understand customer needs and elevate the customer and patient experience in a compliant manner.
  • Collaborate with adjacent field partners, including Field Reimbursement Managers, Territory Managers, and Regional Business Directors, to support customer needs and territory objectives.
  • Share insights, learnings, and best practices with field leadership and internal teams, including Marketing, Training, Field Operations, and Analytics.
  • Provide timely market intelligence, customer insights, and competitive updates.
  • Support regional meetings, launch initiatives, and company-sponsored programs.
  • Operate with integrity and in compliance with company policies, industry regulations, and legal requirements.
  • Demonstrate professionalism, accountability, and ethical conduct in all customer interactions.
  • Consistently embody the company's values of collaboration, integrity, quality, trust, and urgency.
Desired Qualifications
  • Three or more years of pharmaceutical or biotechnology sales experience; other relevant sales experience will also be considered.
  • Specialty sales experience in cardiometabolic markets.
  • Prior product launch experience.

About the company

M

Mineralys Therapeutics

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Mineralys Therapeutics develops targeted treatments for diseases driven by dysregulated aldosterone to help lower blood pressure. Its lead drug, lorundrostat, is an oral aldosterone synthase inhibitor that blocks the CYP11B2 enzyme to reduce aldosterone production, with high selectivity over cortisol. It is advancing through late-stage trials (Phase 3) to treat hypertension-related conditions, CKD, and potentially OSA, using funds from its IPO to support trials, manufacturing, and commercialization preparation. By focusing on a selective mechanism that avoids large cortisol disruption, Mineralys differentiates itself from older MRAs and aims to address a large potential market, estimated to exceed $200 billion by 2030.

Company Size

51-200

Company Stage

IPO

Headquarters

Radnor Township, Pennsylvania

Founded

2020

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Simplify's Take

What believers are saying

  • FDA accepted lorundrostat NDA on March 9, 2026, with December 22 PDUFA.
  • Q2 2026 showed commercial readiness: sales hiring, market access, and payer engagement.
  • Lorundrostat posted 52.2% placebo-adjusted UACR reduction in CKD albuminuria at 12 weeks.

What critics are saying

  • AstraZeneca's Baxfendy approved May 18, 2026, grabbing first-mover advantage before Mineralys.
  • December 22, 2026 PDUFA leaves one binary FDA decision; rejection kills the launch.
  • If lorundrostat misses approval, Mineralys becomes a cash-burning single-asset biotech.

What makes Mineralys Therapeutics unique

  • Lorundrostat directly inhibits CYP11B2, targeting aldosterone source instead of receptor blockade.
  • Launch-HTN enrolled 800 patients and showed CKD-aligned blood-pressure and albuminuria reductions.
  • Mineralys now owns lorundrostat royalties and IP after the June 2026 Tanabe buyout.

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Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • 401(k) Retirement Plan
  • Remote Work Options
  • Unlimited Paid Time Off
  • Flexible Work Hours
  • Hybrid Work Options
  • 401(k) Company Match
  • Wellness Program
  • Mental Health Support
  • Gym Membership

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

-4%

2 year growth

-1%
Associated Press
Oct 19th, 2026
Mineralys adds Kristine Peterson and Lonnel Coats to board ahead of lorundrostat launch

Mineralys Therapeutics has added Kristine Peterson and Lonnel Coats to its board of directors, the biopharmaceutical company announced on October 19, 2026. The Radnor, Pennsylvania-based company is preparing for the potential approval and commercial launch of lorundrostat, a treatment for uncontrolled or resistant hypertension. Peterson was most recently chief executive officer of Valeritas. She also spent 20 years at Bristol-Myers Squibb and held senior roles at Johnson & Johnson and Biovail. Coats was most recently chief executive officer of Lexicon Pharmaceuticals. He previously led Eisai's North American business and spent eight years at Janssen Pharmaceuticals. Chief executive officer Jon Congleton said their commercial experience will help as Mineralys becomes a commercial-stage company.

MarketBeat
Sep 17th, 2026
Insider selling: Mineralys Therapeutics (NASDAQ:MLYS) director sells $85,740.00 in stock.

Insider selling: Mineralys Therapeutics (NASDAQ:MLYS) director sells $85,740.00 in stock. September 17, 2026 Key points. * Director sale: Daphne Karydas sold 3,000 Mineralys Therapeutics shares for approximately $85,740 under a pre-arranged Rule 10b5-1 plan, reducing her direct ownership by 32.61% to 6,200 shares. * Stock and financial performance: MLYS recently traded at $27.98, with a $2.47 billion market capitalization. The company reported a quarterly loss of $2.85 per share, significantly missing the $0.55 consensus estimate. * Analyst outlook: Despite mixed ratings, including hold and sell calls, the stock has a consensus "Moderate Buy" rating and an average price target of $48.80; institutional investors own 84.46% of the shares. * MarketBeat previews the top five stocks to own by October 1st. Mineralys Therapeutics, Inc. (NASDAQ:MLYS - Get Free Report) Director Daphne Karydas sold 3,000 shares of the business's stock in a transaction that occurred on Tuesday, September 15th. The stock was sold at an average price of $28.58, for a total value of $85,740.00. Following the completion of the transaction, the director directly owned 6,200 shares in the company, valued at approximately $177,196. This represents a 32.61% decrease in their ownership of the stock. The transaction was disclosed in a filing with the SEC, which can be accessed through this hyperlink. The transaction was executed under a pre-arranged Rule 10b5-1 trading plan. Mineralys Therapeutics price performance. Shares of NASDAQ:MLYS traded up $0.44 during mid-day trading on Thursday, reaching $27.98. The stock had a trading volume of 1,141,567 shares, compared to its average volume of 1,267,498. The business's 50 day moving average price is $27.15 and its 200 day moving average price is $27.12. Mineralys Therapeutics, Inc. has a 1 year low of $22.30 and a 1 year high of $47.65. The company has a market cap of $2.47 billion, a P/E ratio of -6.60 and a beta of 0.68. The company has a current ratio of 34.46, a quick ratio of 34.46 and a debt-to-equity ratio of 0.18. Mineralys Therapeutics (NASDAQ:MLYS - Get Free Report) last released its quarterly earnings data on Wednesday, August 12th. The company reported ($2.85) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($0.55) by ($2.30). Research analysts expect that Mineralys Therapeutics, Inc. will post -4.45 EPS for the current fiscal year. Hedge funds weigh in on Mineralys Therapeutics. A number of large investors have recently made changes to their positions in the company. Timothy G. Youngquist 2020 Irrevocable Trust bought a new stake in Mineralys Therapeutics in the second quarter worth about $2,721,000. TimesSquare Capital Management LLC purchased a new position in Mineralys Therapeutics during the 2nd quarter valued at $6,363,000. Bank of America Corp DE grew its position in Mineralys Therapeutics by 11.5% in the 1st quarter. Bank of America Corp DE now owns 1,100,372 shares of the company's stock valued at $29,809,000 after acquiring an additional 113,092 shares during the last quarter. Man Group plc purchased a new stake in Mineralys Therapeutics in the second quarter worth $1,609,000. Finally, Artia Global Partners LP increased its stake in Mineralys Therapeutics by 143.5% in the fourth quarter. Artia Global Partners LP now owns 137,800 shares of the company's stock worth $5,001,000 after purchasing an additional 81,200 shares during the period. 84.46% of the stock is owned by hedge funds and other institutional investors. Wall Street Analyst weigh in. MLYS has been the subject of several research reports. Jefferies Financial Group reissued a "hold" rating on shares of Mineralys Therapeutics in a research note on Monday, June 1st. Weiss Ratings restated a "sell (d-)" rating on shares of Mineralys Therapeutics in a research report on Friday, July 17th. Wall Street Zen downgraded shares of Mineralys Therapeutics from a "sell" rating to a "strong sell" rating in a report on Saturday, August 15th. Zacks Research upgraded Mineralys Therapeutics from a "strong sell" rating to a "hold" rating in a research report on Friday, September 11th. Finally, HC Wainwright restated a "buy" rating on shares of Mineralys Therapeutics in a research report on Monday, June 1st. Five analysts have rated the stock with a Buy rating, two have assigned a Hold rating and one has given a Sell rating to the company. According to MarketBeat, Mineralys Therapeutics has a consensus rating of "Moderate Buy" and an average target price of $48.80. Discover more Financial News Self-Help & Motivational Mineralys Therapeutics company profile. Mineralys Therapeutics, Inc is a clinical-stage biopharmaceutical company focused on developing therapies for cardiovascular and kidney-related diseases. The company's research is centered on conditions associated with excess aldosterone activity, including uncontrolled and resistant hypertension. Mineralys' lead investigational product is lorundrostat, also known as MLS-101, an oral, highly selective aldosterone synthase inhibitor. The company is evaluating lorundrostat in clinical studies as a potential treatment for patients whose blood pressure remains inadequately controlled despite existing therapy. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. Before you consider Mineralys Therapeutics, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Mineralys Therapeutics wasn't on the list. While Mineralys Therapeutics currently has a Moderate Buy rating among analysts, top-rated analysts believe these five stocks are better buys. Enter your email address and we'll send you MarketBeat's list of ten stocks set to soar in Fall 2026, despite the economic uncertainty rattling markets right now. These ten stocks are incredibly resilient and are likely to thrive in any economic environment. Continue following MarketBeat

MyChesCo
Sep 15th, 2026
Mineralys grants equity awards to two new employees.

Mineralys grants equity awards to two new employees. RADNOR, PA - Mineralys Therapeutics Inc. (Nasdaq: MLYS) granted stock options and restricted stock units covering a combined 52,080 shares to two newly hired non-executive employees as employment inducements under Nasdaq listing rules. The company's board compensation committee approved options covering 29,760 shares and restricted stock units covering 22,320 shares on Sept. 8. The awards were issued under Mineralys' 2025 Employment Inducement Incentive Award Plan and were granted as an inducement material to the employees joining the company in accordance with Nasdaq Listing Rule 5635(c)(4). The stock options vest over four years. Twenty-five percent of the shares underlying the options will vest on the first anniversary of the Sept. 8 vesting commencement date, followed by 1/48th of the shares after each subsequent month, subject to continued employment. The restricted stock units also vest over four years, with 25% vesting on each of the first four anniversaries of the Sept. 8 commencement date, subject to continued service. Mineralys is developing treatments targeting hypertension and conditions associated with dysregulated aldosterone, including chronic kidney disease and obstructive sleep apnea. Its initial product candidate, lorundrostat, is an investigational oral aldosterone synthase inhibitor. The Radnor-based biopharmaceutical company was founded by Catalys Pacific. Support the local news that supports Chester County. MyChesCo delivers reliable, fact-based reporting and essential community resources - free for everyone. If you value that, click here to become a patron today. Discover more Download Interactive Maps Follow Federal Policy

Yahoo Finance
Aug 12th, 2026
Mineralys acquires royalty rights for $200M, secures $500M loan ahead of lorundrostat launch

Mineralys Therapeutics paid $200 million upfront to repurchase future royalty payments from Mitsubishi Tanabe for its hypertension drug lorundrostat, aiming to maximise long-term equity value ahead of commercialisation. The company also secured a $500 million senior secured term loan facility and completed a $150 million equity offering in Q2 2026. New clinical data from the LAUNCH-HTN trial showed lorundrostat achieved a 52% placebo-adjusted reduction in UACR for chronic kidney disease patients. The company is targeting a 22 December 2026 PDUFA date and plans to have its sales force ready before potential approval. R&D expenses rose to $221.4 million in Q2 2026, largely due to the $200 million royalty repurchase payment. Management said market research suggests physicians prefer lorundrostat over competitor baxdrostat by a 2-to-1 margin based on efficacy and safety signals.

Yahoo Finance
Aug 12th, 2026
Mineralys Therapeutics reports $661M cash as Q2 net loss hits $241M on $200M Tanabe buyout

Mineralys Therapeutics reported a net loss of $241.1 million for Q2 2026, compared to $43.3 million in the same period last year, primarily driven by a $200 million upfront payment to Tanabe Pharma to repurchase future royalty payments. The company also faces up to $100 million in milestone payments. Despite the loss, Mineralys maintained a strong cash position of $661.4 million as of 30 June 2026, up from $656.6 million at year-end 2025. The company secured additional funding through a $150 million equity offering and a $500 million senior secured term loan facility. R&D expenses jumped to $221.4 million from $38.3 million year-over-year, whilst G&A expenses rose to $24.7 million from $8.5 million, driven by higher professional fees and personnel costs. The company is preparing for the commercial launch of lorundrostat ahead of the December PDUFA date.