Full-Time

Founding Machine Learning Scientist

Tabula

Tabula

Develops ML-guided, programmable antimicrobials

No salary listed

San Francisco, CA, USA

In Person

On-site role in San Francisco office; remote not available.

Category
AI & Machine Learning (1)
Required Skills
Python
Neural Networks
Pytorch
Machine Learning
Requirements
  • Strong background in modern machine learning and deep learning
  • Fluency in Python and PyTorch, plus comfort with the broader modern ML stack
  • Ability to reason clearly about model architectures, training, evaluation, and tradeoffs
  • Good research judgment about which ideas are worth testing and how to evaluate them
  • Comfort working in an early-stage environment where the problems are hard and the path is still being defined
  • Ability to work closely with domain experts outside ML
  • Strong interest in applying machine learning to a problem in the physical world, not just at the software layer
Responsibilities
  • Design and run model experiments against difficult biological data
  • Help define the research roadmap for how Tabula’s models should improve over time
  • Work closely with the lab to shape what data gets generated and why
  • Build better practices around experimentation, evaluation, and reproducibility
  • Contribute to technical decisions around model design, training, and research direction
  • Help a small team build an AI company whose output is not content or software alone, but real therapies for real patients
Desired Qualifications
  • You have done substantial model development work, not just built products on top of model APIs
  • You like designing experiments and learning from ambiguous results
  • You are excited by the idea of using AI for something more concrete than the usual software treadmill
  • You want your work to be tied to outcomes in the real world
  • You are interested in helping build a company where machine learning is central, not decorative

Tabula Bioscience uses machine learning to improve disease prediction and personalized medicine. Its core product aims to design programmable, strain-specific antimicrobials that target bacteria via bacteriophages, with R&D focused on phage therapy and gram-negative bacteria. The models leverage unlabeled genomic data from humans and other species, incorporate expert priors and epigenetic information, and use probabilistic programming to build mechanistic biological explanations. The goal is to narrow the gap between heritability and prediction to enable more effective, individualized treatments.

Company Size

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Company Stage

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Total Funding

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Headquarters

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Founded

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Simplify Jobs

Simplify's Take

What believers are saying

  • Tabula's data strategy aligns with the 2026 EvORanker AI breakthrough validating cross-species gene evolution.
  • AlphaFold3 released May 2024 accelerates drug design for Tabula's gram-negative bacterial challenges.
  • RoseTTAFold All-Atom enables rapid generation of tailored bacteriophage therapeutics for Tabula.

What critics are saying

  • Chinese state-sponsored biotech firms are flooding Tabula's pipeline with cheap, fast-developed molecules.
  • AI-enabled offensive cyberattacks targeting Tabula's proprietary ML models pose a critical biosecurity threat.
  • Gilead's $11.9B acquisition of Kite Pharma redirects capital from precision antimicrobials to cell therapies.

What makes Tabula unique

  • Tabula uses probabilistic programming to integrate unlabeled cross-species genomic data for disease modeling.
  • Tabula designs strain-specific antimicrobials using bacteriophages targeting gram-negative bacteria with AI.
  • Tabula combines epigenetic data and 3D DNA priors in its machine learning architecture.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Paid Vacation

401(k) Company Match