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Drug Hunter

Distills drug discovery research for industry scientists

Director, Scientific Data & Informatics

Data ManagementConfirmed live in the last 24 hours
Full-timeRemote in USA

About the Job

Requirements

  • A PhD in cheminformatics, bioinformatics, computational biology, structural biology, or a related quantitative life-science field.
  • At least 10 years working with scientific data in drug discovery, biotech, or life science data/informatics companies, including at least 3 years leading people or a data function.
  • Working cheminformatics literacy, including molecular representations, structure standardization, substructure and similarity search concepts, and RDKit or similar tools.
  • Fluency in bioinformatics, with deep working knowledge of biological databases and ontologies, target and pathway biology, and gene/protein identifier mapping.
  • Strong data modeling skills and hands-on proficiency in Python and SQL; experience with data pipelines and modern data tooling.
  • Understanding of the drug discovery process from target to clinic and ability to converse fluently with medicinal chemists and biologists.

Responsibilities

  • Serve as the primary internal subject-matter expert for cheminformatics and scientific data, with sufficient breadth across bioinformatics and drug discovery data to guide data decisions spanning chemistry and biology.
  • Own the scientific strategy for acquiring, representing, integrating, normalizing, and maintaining scientific data, partnering with Engineering on the architecture and systems that operationalize the strategy and Science on automated and manual data curation processes.
  • Define how chemical entities are represented, registered, standardized, and resolved across sources, and establish curation standards, controlled vocabularies, quality assurance rules, and tooling that enables data curation at scale.
  • Define approaches for extracting structured scientific information from unstructured content, including chemical structures, text, and tables from literature and patents, and establish how extracted information should be linked to canonical entities.
  • Own the scientific semantics, entity resolution, and ontology strategy that unifies compound synonyms, target and gene nomenclature, disease terms, organizations, assays, and other scientific concepts across sources, including approaches for handling ambiguity and conflicting source assertions.
  • Evaluate scientific data sources across chemistry, biology, DMPK, drug, and clinical domains, assessing coverage, scientific quality, overlap, limitations, licensing considerations, and update characteristics, and determine how they should contribute to Drug Hunter's data.
  • Establish standards for scientific data quality, provenance, validation, completeness, and freshness, and ensure the Data team has effective processes for identifying and resolving data-quality issues.
  • Partner with Science to translate scientific expertise and curation decisions into consistent, maintainable data models, standards, and processes.
  • Partner with Engineering to define data models and technical approaches that accurately represent complex scientific information and support the platform, jointly evaluating architectural decisions and trade-offs where data and application systems intersect.
  • Partner with Product Management to translate scientific and technical requirements into project specifications for the data team and communicate the trade-offs of technical decisions.
  • Evaluate build-versus-buy decisions for scientific datasets, cheminformatics and bioinformatics capabilities, and data tooling, partnering with Engineering where decisions involve shared technical infrastructure or application architecture.
  • Lead the Data team in translating scientific data priorities into executable projects, remaining involved in day-to-day work to understand progress, technical challenges, dependencies, and workload.
  • Provide scientific and technical leadership, mentorship, and direction to the Data team, creating, hiring, and managing roles as needed.

About the Company

Drug Hunter

Distills drug discovery research for industry scientists

Drug Hunter runs a subscription knowledge platform for scientists and research teams working to discover medicines. Its team of industry scientists reads journals, patents and conference abstracts, then distills the most useful lessons into searchable articles, molecule profiles and case studies on problems such as potency, toxicity and drug exposure. Members can search chemical structures across approved drugs, clinical compounds and recent disclosures, and a mobile app and a drug discovery course extend the service. Organizations buy subscriptions for their research staff, while a free newsletter introduces the content to a wider audience. Drug Hunter was founded in 2018 and is headquartered in Portland, Oregon.

Company size
11-50
Company stage
Not listed
Total funding
Not listed
Headquarters
Portland, OR
Founded
2018

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