Full-Time

Technical Project Manager

Multiple Teams

Posted on 10/21/2025

Guardant Health

Guardant Health

1,001-5,000 employees

FDA-approved blood-based cancer diagnostics provider

No salary listed

Palo Alto, CA, USA

In Person

Category
Business & Strategy (2)
,
Required Skills
JIRA
SCRUM
Confluence
Requirements
  • 7+ years of experience as a Technical Project Manager, Agile Project Manager, or Scrum Master in a software development environment.
  • Proven ability to drive Agile development processes and scrum teams in a fast-paced, cross-functional environment.
  • Strong proficiency in Jira, Confluence, and Agile project tracking tools.
  • Experience establishing sprint goals, managing sprint backlog, and tracking progress against launch timelines.
  • Excellent attention to detail, problem-solving skills, and ability to identify and mitigate risks.
  • Strong verbal and written communication skills, with the ability to engage both technical and non-technical stakeholders.
Responsibilities
  • Lead and facilitate scrum ceremonies including sprint planning, daily stand-ups, sprint reviews, and retrospectives.
  • Work with Product and Engineering teams to define and establish sprint goals and ensure clear alignment with the overall roadmap.
  • Remove blockers, identify dependencies, and ensure teams stay focused on execution.
  • Create and maintain visibility into the roadmap, ensuring stakeholders have clear insight into project milestones, target launch dates, and dependencies.
  • Track progress against launch timelines and proactively identify risks, escalating when necessary.
  • Partner with Product Managers and Engineering leads to align priorities, scope, and deliverables.
  • Leverage Jira, Confluence, and other Agile tools to track progress, manage backlog refinement, and ensure accurate reporting.
  • Establish and enforce the best practices for sprint planning, release management, and delivery tracking.
  • Continuously evaluate and refine project management processes to improve team efficiency and collaboration.
  • Act as the bridge between Engineering, Product, and business stakeholders, ensuring seamless communication and alignment.
  • Provide regular status updates, reports, and presentations on project progress, risks, and mitigation plans.
  • Facilitate cross-team collaboration, ensuring dependencies are managed and expectations are clearly set.
Desired Qualifications
  • Experience in Life Sciences, Healthcare, or HealthTech industries.
  • Familiarity with EMR/EHR integrations (Epic, OncoEMR, HL7, FHIR).
  • Background in cloud-native applications, DevOps, and CI/CD best practices.

Guardant Health develops blood-based cancer diagnostics and sells tests to healthcare providers and research institutions. Its flagship product, Guardant360, uses a liquid biopsy to analyze tumor DNA circulating in a patient’s blood to detect mutations and guide treatment decisions for advanced cancer. The company is expanding into early detection and recurrence monitoring, with tests designed to be non-invasive and data-rich for cancer management. Compared with competitors, Guardant Health emphasizes a widely adopted, FDA-approved liquid biopsy platform with broad cancer-type coverage and a focus on providing actionable genomic insights to clinicians. Its goal is to improve cancer outcomes by enabling non-invasive, data-driven decision making across stages of disease and over time.

Company Size

1,001-5,000

Company Stage

IPO

Headquarters

Palo Alto, California

Founded

2012

Simplify Jobs

Simplify's Take

What believers are saying

  • Q1 2026 revenue surged 48% to $302M, raising FY guidance to $1.30-1.32B.
  • Nuvalent collaboration on April 30, 2026, expands CDx for NSCLC therapies.
  • Verana Health partnership on March 24, 2026, accelerates biomarker therapy development.

What critics are saying

  • Illumina Grail Galleri erodes Shield share in $18B screening market within 12 months.
  • FoundationOne Liquid CDx captures Guardant360 volume via Roche sales force.
  • $112M Q1 2026 net loss exhausts $1.2B cash before 2027 breakeven.

What makes Guardant Health unique

  • Guardant360 CDx holds 26 FDA companion diagnostic approvals across tumor types.
  • Guardant Infinity platform combines tissue and liquid biopsies for biopharma trials.
  • Shield test targets $18B colorectal screening with Quest Diagnostics partnership.

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Benefits

Professional Development Budget

Performance Bonus

Growth & Insights and Company News

Headcount

6 month growth

-1%

1 year growth

0%

2 year growth

-1%
360Dx
Apr 30th, 2026
Guardant Health, Nuvalent ink oncology companion diagnostic development pact.

Guardant Health, Nuvalent ink oncology companion diagnostic development pact. NEW YORK - Guardant Health announced on Thursday that it has entered into a multi-year strategic collaboration with biopharma company Nuvalent to develop and potentially commercialize companion diagnostics for oncology. Get the full story with 360dx Premium. Only $95 for the first 90 days. Full site access Interest-based email alerts Premium Access - Trial Offer $95.00 for 3 month

Medical Laboratory Observer
Apr 6th, 2026
Inside Quest Diagnostics' daytime kidney care lab strategy.

Inside Quest Diagnostics' daytime kidney care lab strategy. In this exclusive interview, Quest Diagnostics' Ines Dahne-Steuber discusses their daytime kidney care lab strategy with MLO Editor in Chief, Christina Wichmann. April 6, 2026 Ines Dahne-Steuber is Vice President and General Manager of Kidney Care at Quest Diagnostics. Most recently, Ines served as Chief Operating Officer for Guardant Health. Prior to that, she served as SVP of Operational Excellence and President of Spectra Labs for Fresenius Medical Care. Ines previously worked at Quest Diagnostics from 2005-2015 in several roles, including as VP of Process Excellence and Healthcare IT. She earned bachelor's and master's degrees in Modern Chinese and Romance Studies from Humboldt-University in Berlin, Germany. MLO: dialysis patients have unique and often complex testing needs. How has Quest Diagnostics adapted its daytime operations to better support this population, and what operational changes have made the biggest impact on patient care? Dahne-Steuber: Quest operates major clinical laboratories all over the U.S., so Mlo Online is well positioned to serve patients in their local communities, wherever they live. To best accommodate the unique needs of dialysis patients, Mlo Online has chosen to perform testing at all 16 participating Quest Diagnostics labs during daytime operations so that staff can give these samples special attention without impacting other patient testing commitments. Dialysis patients have unique physiologies, which lead to more clotted samples. These clots can impact testing performance and need to be managed diligently.

Yahoo Finance
Mar 31st, 2026
Guardant Health (GH) and Verana Health announces new partnership.

Guardant Health (GH) and Verana Health announces new partnership. Noor Ul Ain Rehman Guardant Health, Inc. (NASDAQ:GH) is one of the best high growth healthcare stocks to buy now. Guardant Health, Inc. (NASDAQ:GH) and Verana Health announced on March 24 a new partnership aimed at allowing biopharmaceutical researchers to access the combined resources of Guardant's clinicogenomic testing data and Verana's regulatory-grade, therapeutic-specific EHR curated datasets to expedite the development of new therapies and enhance ongoing patient care. Management stated that the collaboration provides extensive datasets that would allow research scientists to easily understand and validate correlations between molecular biomarkers, treatment decisions, and clinical outcomes. Craig Eagle, MD, Guardant Health, Inc. (NASDAQ:GH) chief medical officer, stated that the real-world data partnership with Verana marks a considerable milestone in the company's mission to advance novel therapies, in particular cancer, with data. He added that allowing "biopharmaceutical researchers the ability to connect detailed information about tumor biology and therapy response with real-world patient outcome data" would accelerate the discovery of new biomarker-based therapies for patients, helping make the drug development process more economical. Guardant Health, Inc. (NASDAQ:GH) is a precision oncology company specializing in treating cancer through vast data sets, proprietary blood-based tests, and advanced analytics. The company's solutions include recurrence detection, early detection, and treatment selection. While Need2learnchinese acknowledge the potential of GH as an investment, Need2learnchinese believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see its free report on the best short-term AI stock.

Healthcare Asia Magazine
Mar 27th, 2026
Guardant Health wins at Healthcare Asia Medtech Awards 2026.

Guardant Health wins at Healthcare Asia Medtech Awards 2026. The ShieldTM Multi-cancer Detection (MCD) test offers screening for 10 types of cancers with just a blood draw. Guardant Health Pte Ltd won Oncology Product Innovation of the Year in the Healthcare Asia Medtech Awards 2026 for the Shield MCD test. The Shield MCD test detects multiple cancer types from DNA shed in the blood. The Shield MCD test is a methylation-based blood test for the detection of multiple cancer types, including bladder, colorectal, breast, prostate, esophageal, gastric, liver, lung, ovarian, and pancreatic cancer in individuals aged 45 years or older without a known diagnosis of cancer, and it is not indicated for use in pregnant women. In the United States, the Shield MCD test has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA). Data from the 2025 American Association for Cancer Research annual meeting showed that the Shield MCD test achieved 99% overall specificity and 74% sensitivity across six aggressive cancers, including esophageal-gastric, hepatocellular, lung, ovarian, and pancreatic. The test also predicted cancer signals of origin with 93% accuracy. The FDA Breakthrough Device designation referenced eight cancer types - bladder, colorectal, esophageal, gastric, liver, lung, ovarian, and pancreatic cancer - in individuals aged 45 or older who are at typical average risk for cancer, as defined by the agency at the time of designation. This designation does not imply FDA approval, clearance, or endorsement of the device's safety or effectiveness. Join Healthcare Asia Magazine community The Healthcare Asia Medtech Awards honours the most exemplary medtech companies across Asia. It serves as a platform for organisations to showcase their pioneering medical devices, life-saving software, or top-notch healthcare solutions, amongst other innovations. Laboratory and test information: The Shield MCD is a laboratory-developed test that was developed and whose performance characteristics were determined by Guardant Health, Inc. This test may be used for clinical purposes and should not be regarded as investigational or for research only. Guardant Health's clinical laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) as qualified to perform high-complexity clinical laboratory testing and accredited by the College of American Pathologists (CAP). This test is not part of the Shield IVD and has not been cleared or approved by the FDA. For Export Use Only. Not for sale or use in the United States. The Healthcare Asia Medtech Awards is presented by Healthcare Asia Magazine. To view the full list of winners, click here. If you want to join the 2027 awards programme and be acclaimed for your organisation's initiatives and contribution to enhancing the industry's overall performance, please contact Julie Anne Nuñez-Difuntorum at [email protected].

Yahoo Finance
Mar 18th, 2026
Guardant Health shares gain 43% upside target as Quest partnership boosts screening growth story

Guardant Health has received a Moderate Buy consensus from 23 analysts, with an average price target of $122.57, implying 43% upside from its recent share price of $85.49. Piper Sandler maintained a Buy rating with a $130 target following recent company presentations. The precision oncology company reported fourth-quarter 2025 revenue of $281.3 million, up 39% year over year, with oncology revenue rising 30% to $189.9 million and screening revenue reaching $35.1 million. Guardant expects total 2026 revenue growth of 27% to 30%. At recent healthcare conferences, management highlighted its Quest Diagnostics partnership for Shield and noted that 90% of Shield users had not been screened in the prior five years, suggesting the product can expand rather than compete within the existing screening market.

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